Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100014 |
Resumo: | OBJECTIVE: To compare optical coherence tomography (OCT) measurements on the retinal nerve fiber layer (RNFL) of healthy controls and patients with longitudinally extensive transverse myelitis (LETM) without previous optic neuritis. METHOD: Twenty-six eyes from 26 patients with LETM and 26 control eyes were subjected to automated perimetry and OCT for comparison of RNFL measurements. RESULTS: The mean deviation values from perimetry were significantly lower in patients with LETM than in controls (p<0.0001). RNFL measurements in the nasal quadrant and in the 3-o'clock segment were significantly smaller in LETM eyes than in controls. (p=0.04 and p=0.006, respectively). No significantly differences in other RNFL measurements were found. CONCLUSION: Patients with LETM may present localized RNFL loss, particularly on the nasal side of the optic disc, associated with slight visual field defects, even in the absence of previous episodes of optic neuritis. These findings emphasize the fact that patients with LETM may experience attacks of subclinical optic nerve damage. |
id |
ABNEURO-1_80d82d0d1da6a8c24e2d9a02e44258cb |
---|---|
oai_identifier_str |
oai:scielo:S0004-282X2011000100014 |
network_acronym_str |
ABNEURO-1 |
network_name_str |
Arquivos de neuro-psiquiatria (Online) |
repository_id_str |
|
spelling |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitistomography, optical coherencetransverse myelitisneuromyelitis opticamultiple sclerosisOBJECTIVE: To compare optical coherence tomography (OCT) measurements on the retinal nerve fiber layer (RNFL) of healthy controls and patients with longitudinally extensive transverse myelitis (LETM) without previous optic neuritis. METHOD: Twenty-six eyes from 26 patients with LETM and 26 control eyes were subjected to automated perimetry and OCT for comparison of RNFL measurements. RESULTS: The mean deviation values from perimetry were significantly lower in patients with LETM than in controls (p<0.0001). RNFL measurements in the nasal quadrant and in the 3-o'clock segment were significantly smaller in LETM eyes than in controls. (p=0.04 and p=0.006, respectively). No significantly differences in other RNFL measurements were found. CONCLUSION: Patients with LETM may present localized RNFL loss, particularly on the nasal side of the optic disc, associated with slight visual field defects, even in the absence of previous episodes of optic neuritis. These findings emphasize the fact that patients with LETM may experience attacks of subclinical optic nerve damage.Academia Brasileira de Neurologia - ABNEURO2011-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100014Arquivos de Neuro-Psiquiatria v.69 n.1 2011reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2011000100014info:eu-repo/semantics/openAccessMoura,Frederico C.Fernandes,Danilo B.Apóstolos-Pereira,Samira L.Callegaro,DagobertoMarchiori,Paulo E.Monteiro,Mário L.R.eng2011-02-18T00:00:00Zoai:scielo:S0004-282X2011000100014Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2011-02-18T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
title |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
spellingShingle |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis Moura,Frederico C. tomography, optical coherence transverse myelitis neuromyelitis optica multiple sclerosis |
title_short |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
title_full |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
title_fullStr |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
title_full_unstemmed |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
title_sort |
Optical coherence tomography evaluation of retinal nerve fiber layer in longitudinally extensive transverse myelitis |
author |
Moura,Frederico C. |
author_facet |
Moura,Frederico C. Fernandes,Danilo B. Apóstolos-Pereira,Samira L. Callegaro,Dagoberto Marchiori,Paulo E. Monteiro,Mário L.R. |
author_role |
author |
author2 |
Fernandes,Danilo B. Apóstolos-Pereira,Samira L. Callegaro,Dagoberto Marchiori,Paulo E. Monteiro,Mário L.R. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Moura,Frederico C. Fernandes,Danilo B. Apóstolos-Pereira,Samira L. Callegaro,Dagoberto Marchiori,Paulo E. Monteiro,Mário L.R. |
dc.subject.por.fl_str_mv |
tomography, optical coherence transverse myelitis neuromyelitis optica multiple sclerosis |
topic |
tomography, optical coherence transverse myelitis neuromyelitis optica multiple sclerosis |
description |
OBJECTIVE: To compare optical coherence tomography (OCT) measurements on the retinal nerve fiber layer (RNFL) of healthy controls and patients with longitudinally extensive transverse myelitis (LETM) without previous optic neuritis. METHOD: Twenty-six eyes from 26 patients with LETM and 26 control eyes were subjected to automated perimetry and OCT for comparison of RNFL measurements. RESULTS: The mean deviation values from perimetry were significantly lower in patients with LETM than in controls (p<0.0001). RNFL measurements in the nasal quadrant and in the 3-o'clock segment were significantly smaller in LETM eyes than in controls. (p=0.04 and p=0.006, respectively). No significantly differences in other RNFL measurements were found. CONCLUSION: Patients with LETM may present localized RNFL loss, particularly on the nasal side of the optic disc, associated with slight visual field defects, even in the absence of previous episodes of optic neuritis. These findings emphasize the fact that patients with LETM may experience attacks of subclinical optic nerve damage. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2011000100014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.69 n.1 2011 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212770166865920 |