Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa

Detalhes bibliográficos
Autor(a) principal: Couto,Eduardo Vieira
Data de Publicação: 2016
Outros Autores: Ballin,Carlos Roberto, Sampaio,Claudia Paraguaçu Pupo, Maeda,Carlos Augusto Seije, Ballin,Carlos Henrique, Dassi,Camila Soares, Yukari Miura,Lilian
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Otorhinolaryngology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000100017
Resumo: ABSTRACT INTRODUCTION: Bismuth subgallate is a salt derived from heavy metal. The aim of this study was to evaluate the effect of this salt on some phases of healing. OBJECTIVES: To assess the effect of subgallate on mucosa and to evaluate the association between the use of bismuth subgallate and neogenesis of vessels in oral mucosal wounds. METHODS: This was a prospective and experimental study. This study used sixty rats, which were divided into control and experimental groups. The animals were submitted to a surgical procedure, which caused oral mucosal injury. A saline solution was applied on the wound of the control group, and in the experimental group, a solution of bismuth subgallate was administrated. RESULTS: The experimental group showed greater inflammatory reaction with increasing monomorphic proliferation. There was increased vessel proliferation in the control group. CONCLUSION: Bismuth subgallate had a negative influence on the healing process, delaying the rate of new vessel formation and optimal wound healing.
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spelling Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosaWound healingTonsillectomyAngiogenesis-inducing agentsABSTRACT INTRODUCTION: Bismuth subgallate is a salt derived from heavy metal. The aim of this study was to evaluate the effect of this salt on some phases of healing. OBJECTIVES: To assess the effect of subgallate on mucosa and to evaluate the association between the use of bismuth subgallate and neogenesis of vessels in oral mucosal wounds. METHODS: This was a prospective and experimental study. This study used sixty rats, which were divided into control and experimental groups. The animals were submitted to a surgical procedure, which caused oral mucosal injury. A saline solution was applied on the wound of the control group, and in the experimental group, a solution of bismuth subgallate was administrated. RESULTS: The experimental group showed greater inflammatory reaction with increasing monomorphic proliferation. There was increased vessel proliferation in the control group. CONCLUSION: Bismuth subgallate had a negative influence on the healing process, delaying the rate of new vessel formation and optimal wound healing.Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.2016-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000100017Brazilian Journal of Otorhinolaryngology v.82 n.1 2016reponame:Brazilian Journal of Otorhinolaryngologyinstname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)instacron:ABORL-CCF10.1016/j.bjorl.2014.12.009info:eu-repo/semantics/openAccessCouto,Eduardo VieiraBallin,Carlos RobertoSampaio,Claudia Paraguaçu PupoMaeda,Carlos Augusto SeijeBallin,Carlos HenriqueDassi,Camila SoaresYukari Miura,Lilianeng2016-03-04T00:00:00Zoai:scielo:S1808-86942016000100017Revistahttp://www.bjorl.org.br/https://old.scielo.br/oai/scielo-oai.phprevista@aborlccf.org.br||revista@aborlccf.org.br1808-86861808-8686opendoar:2016-03-04T00:00Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)false
dc.title.none.fl_str_mv Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
title Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
spellingShingle Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
Couto,Eduardo Vieira
Wound healing
Tonsillectomy
Angiogenesis-inducing agents
title_short Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
title_full Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
title_fullStr Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
title_full_unstemmed Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
title_sort Experimental study on the effects of bismuth subgallate on the inflammatory process and angiogenesis of the oral mucosa
author Couto,Eduardo Vieira
author_facet Couto,Eduardo Vieira
Ballin,Carlos Roberto
Sampaio,Claudia Paraguaçu Pupo
Maeda,Carlos Augusto Seije
Ballin,Carlos Henrique
Dassi,Camila Soares
Yukari Miura,Lilian
author_role author
author2 Ballin,Carlos Roberto
Sampaio,Claudia Paraguaçu Pupo
Maeda,Carlos Augusto Seije
Ballin,Carlos Henrique
Dassi,Camila Soares
Yukari Miura,Lilian
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Couto,Eduardo Vieira
Ballin,Carlos Roberto
Sampaio,Claudia Paraguaçu Pupo
Maeda,Carlos Augusto Seije
Ballin,Carlos Henrique
Dassi,Camila Soares
Yukari Miura,Lilian
dc.subject.por.fl_str_mv Wound healing
Tonsillectomy
Angiogenesis-inducing agents
topic Wound healing
Tonsillectomy
Angiogenesis-inducing agents
description ABSTRACT INTRODUCTION: Bismuth subgallate is a salt derived from heavy metal. The aim of this study was to evaluate the effect of this salt on some phases of healing. OBJECTIVES: To assess the effect of subgallate on mucosa and to evaluate the association between the use of bismuth subgallate and neogenesis of vessels in oral mucosal wounds. METHODS: This was a prospective and experimental study. This study used sixty rats, which were divided into control and experimental groups. The animals were submitted to a surgical procedure, which caused oral mucosal injury. A saline solution was applied on the wound of the control group, and in the experimental group, a solution of bismuth subgallate was administrated. RESULTS: The experimental group showed greater inflammatory reaction with increasing monomorphic proliferation. There was increased vessel proliferation in the control group. CONCLUSION: Bismuth subgallate had a negative influence on the healing process, delaying the rate of new vessel formation and optimal wound healing.
publishDate 2016
dc.date.none.fl_str_mv 2016-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000100017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000100017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjorl.2014.12.009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publisher.none.fl_str_mv Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
dc.source.none.fl_str_mv Brazilian Journal of Otorhinolaryngology v.82 n.1 2016
reponame:Brazilian Journal of Otorhinolaryngology
instname:Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
instname_str Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron_str ABORL-CCF
institution ABORL-CCF
reponame_str Brazilian Journal of Otorhinolaryngology
collection Brazilian Journal of Otorhinolaryngology
repository.name.fl_str_mv Brazilian Journal of Otorhinolaryngology - Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
repository.mail.fl_str_mv revista@aborlccf.org.br||revista@aborlccf.org.br
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