Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration

Detalhes bibliográficos
Autor(a) principal: Siqueira,Lilian de
Data de Publicação: 2019
Outros Autores: Passador,Fábio Roberto, Lobo,Anderson Oliveira, Trichês,Eliandra de Sousa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Polímeros (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100408
Resumo: Abstract Electrospinning is a simple and low-cost way to fabricate fibers. Among the various polymers used in electrospinning, polycaprolactone (PCL) stands out due to its excellent biodegradability and biocompatibility. However, PCL has some limitations such as low bioactivity, hydrophobic surface, and long in vivo degradation. Calcium phosphate ceramics have been recognized as an attractive biomaterial. They are bioactive and osteoinductive, and some are even quite biodegradable. Different contents of particles of beta-tricalcium phosphate (β-TCP) were incorporated in polymer matrix to form fibers of PCL/β-TCP composites by electrospinning for possible application in tissue regeneration. The presence of β-TCP particles promoted some changes in the thermal properties of the fibers. The immersion of PCL/β-TCP 8 wt-% fibers in simulated body fluid (SBF) caused the formation of a denser and homogeneous apatite layer on its surface.
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spelling Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regenerationelectrospinningfiberspolycaprolactonescaffoldstricalcium phosphateAbstract Electrospinning is a simple and low-cost way to fabricate fibers. Among the various polymers used in electrospinning, polycaprolactone (PCL) stands out due to its excellent biodegradability and biocompatibility. However, PCL has some limitations such as low bioactivity, hydrophobic surface, and long in vivo degradation. Calcium phosphate ceramics have been recognized as an attractive biomaterial. They are bioactive and osteoinductive, and some are even quite biodegradable. Different contents of particles of beta-tricalcium phosphate (β-TCP) were incorporated in polymer matrix to form fibers of PCL/β-TCP composites by electrospinning for possible application in tissue regeneration. The presence of β-TCP particles promoted some changes in the thermal properties of the fibers. The immersion of PCL/β-TCP 8 wt-% fibers in simulated body fluid (SBF) caused the formation of a denser and homogeneous apatite layer on its surface.Associação Brasileira de Polímeros2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100408Polímeros v.29 n.1 2019reponame:Polímeros (São Carlos. Online)instname:Associação Brasileira de Polímeros (ABPol)instacron:ABPO10.1590/0104-1428.02118info:eu-repo/semantics/openAccessSiqueira,Lilian dePassador,Fábio RobertoLobo,Anderson OliveiraTrichês,Eliandra de Sousaeng2019-03-13T00:00:00Zoai:scielo:S0104-14282019000100408Revistahttp://www.scielo.br/pohttps://old.scielo.br/oai/scielo-oai.php||revista@abpol.org.br1678-51690104-1428opendoar:2019-03-13T00:00Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)false
dc.title.none.fl_str_mv Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
title Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
spellingShingle Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
Siqueira,Lilian de
electrospinning
fibers
polycaprolactone
scaffolds
tricalcium phosphate
title_short Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
title_full Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
title_fullStr Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
title_full_unstemmed Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
title_sort Morphological, thermal and bioactivity evaluation of electrospun PCL/β-TCP fibers for tissue regeneration
author Siqueira,Lilian de
author_facet Siqueira,Lilian de
Passador,Fábio Roberto
Lobo,Anderson Oliveira
Trichês,Eliandra de Sousa
author_role author
author2 Passador,Fábio Roberto
Lobo,Anderson Oliveira
Trichês,Eliandra de Sousa
author2_role author
author
author
dc.contributor.author.fl_str_mv Siqueira,Lilian de
Passador,Fábio Roberto
Lobo,Anderson Oliveira
Trichês,Eliandra de Sousa
dc.subject.por.fl_str_mv electrospinning
fibers
polycaprolactone
scaffolds
tricalcium phosphate
topic electrospinning
fibers
polycaprolactone
scaffolds
tricalcium phosphate
description Abstract Electrospinning is a simple and low-cost way to fabricate fibers. Among the various polymers used in electrospinning, polycaprolactone (PCL) stands out due to its excellent biodegradability and biocompatibility. However, PCL has some limitations such as low bioactivity, hydrophobic surface, and long in vivo degradation. Calcium phosphate ceramics have been recognized as an attractive biomaterial. They are bioactive and osteoinductive, and some are even quite biodegradable. Different contents of particles of beta-tricalcium phosphate (β-TCP) were incorporated in polymer matrix to form fibers of PCL/β-TCP composites by electrospinning for possible application in tissue regeneration. The presence of β-TCP particles promoted some changes in the thermal properties of the fibers. The immersion of PCL/β-TCP 8 wt-% fibers in simulated body fluid (SBF) caused the formation of a denser and homogeneous apatite layer on its surface.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100408
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282019000100408
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0104-1428.02118
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Polímeros
publisher.none.fl_str_mv Associação Brasileira de Polímeros
dc.source.none.fl_str_mv Polímeros v.29 n.1 2019
reponame:Polímeros (São Carlos. Online)
instname:Associação Brasileira de Polímeros (ABPol)
instacron:ABPO
instname_str Associação Brasileira de Polímeros (ABPol)
instacron_str ABPO
institution ABPO
reponame_str Polímeros (São Carlos. Online)
collection Polímeros (São Carlos. Online)
repository.name.fl_str_mv Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)
repository.mail.fl_str_mv ||revista@abpol.org.br
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