Autoinflammatory syndromes: report on three cases
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500012 |
Resumo: | CONTEXT: Autoinflammatory syndromes are diseases manifested by recurrent episodes of fever and inflammation in multiple organs. There is no production of autoantibodies, but interleukins play an important role and acute-phase reactants show abnormalities. Our aim was to report on three cases of autoinflammatory syndromes that are considered to be rare entities. CASE REPORTS: The authors describe the clinical features of three patients whose diagnosis were the following: tumor necrosis factor receptor-associated periodic syndrome (TRAPS), chronic infantile neurological cutaneous articular (CINCA) syndrome and familial Mediterranean fever (FMF). All of the patients presented fever, joint or bone involvement and increased acute phase reactants. The genetic analysis confirmed the diagnoses of two patients. The great diversity of manifestations and the difficulties in genetic analyses make the diagnosing of these diseases a challenge. |
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Autoinflammatory syndromes: report on three casesRelapsing feverFamilial mediterranean feverTumor necrosis factor-alphaChildNLRP3 protein, human [substance name]InflammationCONTEXT: Autoinflammatory syndromes are diseases manifested by recurrent episodes of fever and inflammation in multiple organs. There is no production of autoantibodies, but interleukins play an important role and acute-phase reactants show abnormalities. Our aim was to report on three cases of autoinflammatory syndromes that are considered to be rare entities. CASE REPORTS: The authors describe the clinical features of three patients whose diagnosis were the following: tumor necrosis factor receptor-associated periodic syndrome (TRAPS), chronic infantile neurological cutaneous articular (CINCA) syndrome and familial Mediterranean fever (FMF). All of the patients presented fever, joint or bone involvement and increased acute phase reactants. The genetic analysis confirmed the diagnoses of two patients. The great diversity of manifestations and the difficulties in genetic analyses make the diagnosing of these diseases a challenge.Associação Paulista de Medicina - APM2009-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500012Sao Paulo Medical Journal v.127 n.5 2009reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802009000500012info:eu-repo/semantics/openAccessMatos,Thais CunhaTerreri,Maria Teresa Ramos AscensãoPetry,Daniela GerentBarbosa,Cássia MariaLen,Claudio ArnaldoHilário,Maria Odete Esteveseng2010-02-03T00:00:00Zoai:scielo:S1516-31802009000500012Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2010-02-03T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Autoinflammatory syndromes: report on three cases |
title |
Autoinflammatory syndromes: report on three cases |
spellingShingle |
Autoinflammatory syndromes: report on three cases Matos,Thais Cunha Relapsing fever Familial mediterranean fever Tumor necrosis factor-alpha Child NLRP3 protein, human [substance name] Inflammation |
title_short |
Autoinflammatory syndromes: report on three cases |
title_full |
Autoinflammatory syndromes: report on three cases |
title_fullStr |
Autoinflammatory syndromes: report on three cases |
title_full_unstemmed |
Autoinflammatory syndromes: report on three cases |
title_sort |
Autoinflammatory syndromes: report on three cases |
author |
Matos,Thais Cunha |
author_facet |
Matos,Thais Cunha Terreri,Maria Teresa Ramos Ascensão Petry,Daniela Gerent Barbosa,Cássia Maria Len,Claudio Arnaldo Hilário,Maria Odete Esteves |
author_role |
author |
author2 |
Terreri,Maria Teresa Ramos Ascensão Petry,Daniela Gerent Barbosa,Cássia Maria Len,Claudio Arnaldo Hilário,Maria Odete Esteves |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Matos,Thais Cunha Terreri,Maria Teresa Ramos Ascensão Petry,Daniela Gerent Barbosa,Cássia Maria Len,Claudio Arnaldo Hilário,Maria Odete Esteves |
dc.subject.por.fl_str_mv |
Relapsing fever Familial mediterranean fever Tumor necrosis factor-alpha Child NLRP3 protein, human [substance name] Inflammation |
topic |
Relapsing fever Familial mediterranean fever Tumor necrosis factor-alpha Child NLRP3 protein, human [substance name] Inflammation |
description |
CONTEXT: Autoinflammatory syndromes are diseases manifested by recurrent episodes of fever and inflammation in multiple organs. There is no production of autoantibodies, but interleukins play an important role and acute-phase reactants show abnormalities. Our aim was to report on three cases of autoinflammatory syndromes that are considered to be rare entities. CASE REPORTS: The authors describe the clinical features of three patients whose diagnosis were the following: tumor necrosis factor receptor-associated periodic syndrome (TRAPS), chronic infantile neurological cutaneous articular (CINCA) syndrome and familial Mediterranean fever (FMF). All of the patients presented fever, joint or bone involvement and increased acute phase reactants. The genetic analysis confirmed the diagnoses of two patients. The great diversity of manifestations and the difficulties in genetic analyses make the diagnosing of these diseases a challenge. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802009000500012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-31802009000500012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.127 n.5 2009 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209262565851136 |