Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Vassallo,José
Data de Publicação: 2005
Outros Autores: Paes,Roberto Pinto, Soares,Fernando Augusto, Menezes,Yara, Aldred,Vera, Ribeiro,Karina de Cássia Braga, Alves,Antonio Correa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300009
Resumo: CONTEXT AND OBJECTIVE: It is currently asserted that, in industrialized countries, nodular sclerosis is the most frequent type of Hodgkin's lymphoma, in contrast to developing countries, where mixed cellularity and lymphocyte depletion are more frequently seen. The objective was to review histological data from cases of Hodgkin's lymphoma from São Paulo and Campinas cities. DESIGN AND SETTING: Cross-sectional histopathological analysis, in four university hospitals and one cancer care center. METHODS: 1,025 cases diagnosed as Hodgkin's lymphoma between 1990 and 2000 were collected from five institutions; 631 of them (61.5%) had been immunophenotyped using antibodies to CD20, CD3, CD15 and CD30. The relative frequencies of histological types (as informed by the contributing authors, who are hematopathologists in their institutions) were determined according to age and gender. RESULTS: The Hodgkin's lymphoma types were distributed as follows: lymphocyte predominance 4.8%, nodular sclerosis 69.2%, mixed cellularity 21.1% and lymphocyte depletion 4.6%. CONCLUSIONS: The controversy regarding the frequencies of Hodgkin's lymphoma types within the Brazilian setting seems to be due to the small number of cases in previous studies. The present data show a picture close to the situation in the industrialized countries.
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spelling Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, BrazilHodgkin's diseasePathologyClassificationLymphomaNeoplasmsCONTEXT AND OBJECTIVE: It is currently asserted that, in industrialized countries, nodular sclerosis is the most frequent type of Hodgkin's lymphoma, in contrast to developing countries, where mixed cellularity and lymphocyte depletion are more frequently seen. The objective was to review histological data from cases of Hodgkin's lymphoma from São Paulo and Campinas cities. DESIGN AND SETTING: Cross-sectional histopathological analysis, in four university hospitals and one cancer care center. METHODS: 1,025 cases diagnosed as Hodgkin's lymphoma between 1990 and 2000 were collected from five institutions; 631 of them (61.5%) had been immunophenotyped using antibodies to CD20, CD3, CD15 and CD30. The relative frequencies of histological types (as informed by the contributing authors, who are hematopathologists in their institutions) were determined according to age and gender. RESULTS: The Hodgkin's lymphoma types were distributed as follows: lymphocyte predominance 4.8%, nodular sclerosis 69.2%, mixed cellularity 21.1% and lymphocyte depletion 4.6%. CONCLUSIONS: The controversy regarding the frequencies of Hodgkin's lymphoma types within the Brazilian setting seems to be due to the small number of cases in previous studies. The present data show a picture close to the situation in the industrialized countries.Associação Paulista de Medicina - APM2005-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300009Sao Paulo Medical Journal v.123 n.3 2005reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802005000300009info:eu-repo/semantics/openAccessVassallo,JoséPaes,Roberto PintoSoares,Fernando AugustoMenezes,YaraAldred,VeraRibeiro,Karina de Cássia BragaAlves,Antonio Correaeng2006-01-20T00:00:00Zoai:scielo:S1516-31802005000300009Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2006-01-20T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
title Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
spellingShingle Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
Vassallo,José
Hodgkin's disease
Pathology
Classification
Lymphoma
Neoplasms
title_short Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
title_full Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
title_fullStr Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
title_full_unstemmed Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
title_sort Histological classification of 1,025 cases of Hodgkin's lymphoma from the State of São Paulo, Brazil
author Vassallo,José
author_facet Vassallo,José
Paes,Roberto Pinto
Soares,Fernando Augusto
Menezes,Yara
Aldred,Vera
Ribeiro,Karina de Cássia Braga
Alves,Antonio Correa
author_role author
author2 Paes,Roberto Pinto
Soares,Fernando Augusto
Menezes,Yara
Aldred,Vera
Ribeiro,Karina de Cássia Braga
Alves,Antonio Correa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vassallo,José
Paes,Roberto Pinto
Soares,Fernando Augusto
Menezes,Yara
Aldred,Vera
Ribeiro,Karina de Cássia Braga
Alves,Antonio Correa
dc.subject.por.fl_str_mv Hodgkin's disease
Pathology
Classification
Lymphoma
Neoplasms
topic Hodgkin's disease
Pathology
Classification
Lymphoma
Neoplasms
description CONTEXT AND OBJECTIVE: It is currently asserted that, in industrialized countries, nodular sclerosis is the most frequent type of Hodgkin's lymphoma, in contrast to developing countries, where mixed cellularity and lymphocyte depletion are more frequently seen. The objective was to review histological data from cases of Hodgkin's lymphoma from São Paulo and Campinas cities. DESIGN AND SETTING: Cross-sectional histopathological analysis, in four university hospitals and one cancer care center. METHODS: 1,025 cases diagnosed as Hodgkin's lymphoma between 1990 and 2000 were collected from five institutions; 631 of them (61.5%) had been immunophenotyped using antibodies to CD20, CD3, CD15 and CD30. The relative frequencies of histological types (as informed by the contributing authors, who are hematopathologists in their institutions) were determined according to age and gender. RESULTS: The Hodgkin's lymphoma types were distributed as follows: lymphocyte predominance 4.8%, nodular sclerosis 69.2%, mixed cellularity 21.1% and lymphocyte depletion 4.6%. CONCLUSIONS: The controversy regarding the frequencies of Hodgkin's lymphoma types within the Brazilian setting seems to be due to the small number of cases in previous studies. The present data show a picture close to the situation in the industrialized countries.
publishDate 2005
dc.date.none.fl_str_mv 2005-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802005000300009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31802005000300009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.123 n.3 2005
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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