Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant

Detalhes bibliográficos
Autor(a) principal: Kucukevcilioglu,Murat
Data de Publicação: 2015
Outros Autores: Eren,Mustafa, Yolcu,Umit, Sobaci,Gungor
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000200013
Resumo: A 52-year-old woman undergoing azathioprine treatment for rheumatoid arthritis developed acute retinal necrosis a month after intravitreal dexamethasone (Ozurdex ®) implantation for posterior uveitis in the left eye. Varicella zoster virus (VZV) DNA was detected in the anterior chamber and vitreous samples on polymerase chain reaction (PCR) analysis. Retinal detachment occurred despite systemic and intravitreal antiviral therapy. Favorable structural and functional outcomes were achieved after retinal surgery with silicone oil. To the authors’ knowledge, this is the first reported case of acute retinal necrosis following placement of an Ozurdex® implant. Physicians practicing Ozurdex® implantations should be aware of this unusual but devastating complication. Extra caution and frequent follow-up are required in all immunocompromised patients receiving Ozurdex® implantation.
id CBO-2_21ad63a28206714ab0c1c49b7ea07d80
oai_identifier_str oai:scielo:S0004-27492015000200013
network_acronym_str CBO-2
network_name_str Arquivos brasileiros de oftalmologia (Online)
repository_id_str
spelling Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implantRetinal necrosis syndrome, acuteImmunosuppressionIntravitreal injections/methodsDexamethasone/administration & dosageCase reportsA 52-year-old woman undergoing azathioprine treatment for rheumatoid arthritis developed acute retinal necrosis a month after intravitreal dexamethasone (Ozurdex ®) implantation for posterior uveitis in the left eye. Varicella zoster virus (VZV) DNA was detected in the anterior chamber and vitreous samples on polymerase chain reaction (PCR) analysis. Retinal detachment occurred despite systemic and intravitreal antiviral therapy. Favorable structural and functional outcomes were achieved after retinal surgery with silicone oil. To the authors’ knowledge, this is the first reported case of acute retinal necrosis following placement of an Ozurdex® implant. Physicians practicing Ozurdex® implantations should be aware of this unusual but devastating complication. Extra caution and frequent follow-up are required in all immunocompromised patients receiving Ozurdex® implantation.Conselho Brasileiro de Oftalmologia2015-04-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000200013Arquivos Brasileiros de Oftalmologia v.78 n.2 2015reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20150030info:eu-repo/semantics/openAccessKucukevcilioglu,MuratEren,MustafaYolcu,UmitSobaci,Gungoreng2015-04-27T00:00:00Zoai:scielo:S0004-27492015000200013Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2015-04-27T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
title Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
spellingShingle Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
Kucukevcilioglu,Murat
Retinal necrosis syndrome, acute
Immunosuppression
Intravitreal injections/methods
Dexamethasone/administration & dosage
Case reports
title_short Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
title_full Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
title_fullStr Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
title_full_unstemmed Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
title_sort Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant
author Kucukevcilioglu,Murat
author_facet Kucukevcilioglu,Murat
Eren,Mustafa
Yolcu,Umit
Sobaci,Gungor
author_role author
author2 Eren,Mustafa
Yolcu,Umit
Sobaci,Gungor
author2_role author
author
author
dc.contributor.author.fl_str_mv Kucukevcilioglu,Murat
Eren,Mustafa
Yolcu,Umit
Sobaci,Gungor
dc.subject.por.fl_str_mv Retinal necrosis syndrome, acute
Immunosuppression
Intravitreal injections/methods
Dexamethasone/administration & dosage
Case reports
topic Retinal necrosis syndrome, acute
Immunosuppression
Intravitreal injections/methods
Dexamethasone/administration & dosage
Case reports
description A 52-year-old woman undergoing azathioprine treatment for rheumatoid arthritis developed acute retinal necrosis a month after intravitreal dexamethasone (Ozurdex ®) implantation for posterior uveitis in the left eye. Varicella zoster virus (VZV) DNA was detected in the anterior chamber and vitreous samples on polymerase chain reaction (PCR) analysis. Retinal detachment occurred despite systemic and intravitreal antiviral therapy. Favorable structural and functional outcomes were achieved after retinal surgery with silicone oil. To the authors’ knowledge, this is the first reported case of acute retinal necrosis following placement of an Ozurdex® implant. Physicians practicing Ozurdex® implantations should be aware of this unusual but devastating complication. Extra caution and frequent follow-up are required in all immunocompromised patients receiving Ozurdex® implantation.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000200013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000200013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20150030
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.78 n.2 2015
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
_version_ 1754209028551999488

Registros relacionados