Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report

Detalhes bibliográficos
Autor(a) principal: Bastos,André Luís Carvalho de Moura
Data de Publicação: 2008
Outros Autores: Freitas,Bruno de Paula, Villas Boas,Oscar, Ramiro,Alexandre Campelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492008000200030
Resumo: X-linked juvenile retinoschisis (XLRS) is a recessively inherited vitreoretinal degeneration characterized by macular pathology and splitting of the neuroretinal layers that is associated with alterations in the XLRS1 gene. There have been no therapeutic interventions known to be effective for patients with X-linked juvenile retinoschisis, but some studies are trying to determine the importance of dorzolamide for the treatment of foveal lesions in this disease. The authors, using optical coherence tomography, describe findings in a patient with X-linked juvenile retinoschisis, before and after a topical use of dorzolamide. Besides the improvement in his visual acuity, further studies are required to elucidate the real prevalence of nonresponse to dorzolamide and the frequency with which there may be a recurrence of foveal cystic changes during continued treatment.
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spelling Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case reportRetinoschisisRetinal degenerationMacular degenerationTomography, optical coherenceCarbonic anhydrase inhibitors/therapeutic useHumanMaleAdolescentCase reportsX-linked juvenile retinoschisis (XLRS) is a recessively inherited vitreoretinal degeneration characterized by macular pathology and splitting of the neuroretinal layers that is associated with alterations in the XLRS1 gene. There have been no therapeutic interventions known to be effective for patients with X-linked juvenile retinoschisis, but some studies are trying to determine the importance of dorzolamide for the treatment of foveal lesions in this disease. The authors, using optical coherence tomography, describe findings in a patient with X-linked juvenile retinoschisis, before and after a topical use of dorzolamide. Besides the improvement in his visual acuity, further studies are required to elucidate the real prevalence of nonresponse to dorzolamide and the frequency with which there may be a recurrence of foveal cystic changes during continued treatment.Conselho Brasileiro de Oftalmologia2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492008000200030Arquivos Brasileiros de Oftalmologia v.71 n.2 2008reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492008000200030info:eu-repo/semantics/openAccessBastos,André Luís Carvalho de MouraFreitas,Bruno de PaulaVillas Boas,OscarRamiro,Alexandre Campeloeng2008-05-29T00:00:00Zoai:scielo:S0004-27492008000200030Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2008-05-29T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
title Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
spellingShingle Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
Bastos,André Luís Carvalho de Moura
Retinoschisis
Retinal degeneration
Macular degeneration
Tomography, optical coherence
Carbonic anhydrase inhibitors/therapeutic use
Human
Male
Adolescent
Case reports
title_short Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
title_full Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
title_fullStr Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
title_full_unstemmed Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
title_sort Use of topical dorzolamide for patients with X-linked juvenile retinoschisis: case report
author Bastos,André Luís Carvalho de Moura
author_facet Bastos,André Luís Carvalho de Moura
Freitas,Bruno de Paula
Villas Boas,Oscar
Ramiro,Alexandre Campelo
author_role author
author2 Freitas,Bruno de Paula
Villas Boas,Oscar
Ramiro,Alexandre Campelo
author2_role author
author
author
dc.contributor.author.fl_str_mv Bastos,André Luís Carvalho de Moura
Freitas,Bruno de Paula
Villas Boas,Oscar
Ramiro,Alexandre Campelo
dc.subject.por.fl_str_mv Retinoschisis
Retinal degeneration
Macular degeneration
Tomography, optical coherence
Carbonic anhydrase inhibitors/therapeutic use
Human
Male
Adolescent
Case reports
topic Retinoschisis
Retinal degeneration
Macular degeneration
Tomography, optical coherence
Carbonic anhydrase inhibitors/therapeutic use
Human
Male
Adolescent
Case reports
description X-linked juvenile retinoschisis (XLRS) is a recessively inherited vitreoretinal degeneration characterized by macular pathology and splitting of the neuroretinal layers that is associated with alterations in the XLRS1 gene. There have been no therapeutic interventions known to be effective for patients with X-linked juvenile retinoschisis, but some studies are trying to determine the importance of dorzolamide for the treatment of foveal lesions in this disease. The authors, using optical coherence tomography, describe findings in a patient with X-linked juvenile retinoschisis, before and after a topical use of dorzolamide. Besides the improvement in his visual acuity, further studies are required to elucidate the real prevalence of nonresponse to dorzolamide and the frequency with which there may be a recurrence of foveal cystic changes during continued treatment.
publishDate 2008
dc.date.none.fl_str_mv 2008-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492008000200030
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492008000200030
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27492008000200030
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.71 n.2 2008
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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