Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients

Detalhes bibliográficos
Autor(a) principal: Bain,Vera
Data de Publicação: 2022
Outros Autores: Barrientos,Anna Carlota Mott Galvão de Arruda, Suzuki,Lisa, Oliveira,Luiz Antonio Nunes de, Litvinov,Nadia, Peron,Karina Rodrigues, Fernandes,Juliana Folloni, Marques,Heloisa Helena de Sousa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Radiologia Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000200078
Resumo: Abstract Objective: To describe the radiological findings in pediatric patients with hematological or oncological diseases who also have an invasive fungal infection (IFI). Materials and Methods: This was a retrospective study of all patients with IFI admitted to a pediatric hematology and oncology hospital in Brazil between 2008 and 2014. Clinical and demographic data were collected. Chest computed tomography (CT) scans of the patients were reviewed by two independent radiologists. Results: We evaluated the chest CT scans of 40 pediatric patients diagnosed with an IFI. Twenty-seven patients (67.5%) had nodules with the halo sign, seven (17.5%) had cavities, two (5.0%) had nodules without the halo sign, and seven (17.5%) had consolidation. The patients with the halo sign and cavities were older (123 vs. 77 months of age; p = 0.03) and had less severe disease (34% vs. 73%; p = 0.04). Ten patients had a proven IFI: with Aspergillus sp. (n = 4); with Candida sp. (n = 5); or with Fusarium sp. (n = 1). Conclusion: A diagnosis of IFI should be considered in children and adolescents with risk factors and abnormal CT scans, even if the imaging findings are nonspecific.
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spelling Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patientsMycoses/diagnostic imagingChildAdolescentImmunocompromised hostTomographyX-ray computedAbstract Objective: To describe the radiological findings in pediatric patients with hematological or oncological diseases who also have an invasive fungal infection (IFI). Materials and Methods: This was a retrospective study of all patients with IFI admitted to a pediatric hematology and oncology hospital in Brazil between 2008 and 2014. Clinical and demographic data were collected. Chest computed tomography (CT) scans of the patients were reviewed by two independent radiologists. Results: We evaluated the chest CT scans of 40 pediatric patients diagnosed with an IFI. Twenty-seven patients (67.5%) had nodules with the halo sign, seven (17.5%) had cavities, two (5.0%) had nodules without the halo sign, and seven (17.5%) had consolidation. The patients with the halo sign and cavities were older (123 vs. 77 months of age; p = 0.03) and had less severe disease (34% vs. 73%; p = 0.04). Ten patients had a proven IFI: with Aspergillus sp. (n = 4); with Candida sp. (n = 5); or with Fusarium sp. (n = 1). Conclusion: A diagnosis of IFI should be considered in children and adolescents with risk factors and abnormal CT scans, even if the imaging findings are nonspecific.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2022-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000200078Radiologia Brasileira v.55 n.2 2022reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2021.0055info:eu-repo/semantics/openAccessBain,VeraBarrientos,Anna Carlota Mott Galvão de ArrudaSuzuki,LisaOliveira,Luiz Antonio Nunes deLitvinov,NadiaPeron,Karina RodriguesFernandes,Juliana FolloniMarques,Heloisa Helena de Sousaeng2022-05-20T00:00:00Zoai:scielo:S0100-39842022000200078Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2022-05-20T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false
dc.title.none.fl_str_mv Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
title Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
spellingShingle Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
Bain,Vera
Mycoses/diagnostic imaging
Child
Adolescent
Immunocompromised host
Tomography
X-ray computed
title_short Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
title_full Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
title_fullStr Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
title_full_unstemmed Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
title_sort Radiological patterns of pulmonary fungal infection in pediatric hematology and oncology patients
author Bain,Vera
author_facet Bain,Vera
Barrientos,Anna Carlota Mott Galvão de Arruda
Suzuki,Lisa
Oliveira,Luiz Antonio Nunes de
Litvinov,Nadia
Peron,Karina Rodrigues
Fernandes,Juliana Folloni
Marques,Heloisa Helena de Sousa
author_role author
author2 Barrientos,Anna Carlota Mott Galvão de Arruda
Suzuki,Lisa
Oliveira,Luiz Antonio Nunes de
Litvinov,Nadia
Peron,Karina Rodrigues
Fernandes,Juliana Folloni
Marques,Heloisa Helena de Sousa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bain,Vera
Barrientos,Anna Carlota Mott Galvão de Arruda
Suzuki,Lisa
Oliveira,Luiz Antonio Nunes de
Litvinov,Nadia
Peron,Karina Rodrigues
Fernandes,Juliana Folloni
Marques,Heloisa Helena de Sousa
dc.subject.por.fl_str_mv Mycoses/diagnostic imaging
Child
Adolescent
Immunocompromised host
Tomography
X-ray computed
topic Mycoses/diagnostic imaging
Child
Adolescent
Immunocompromised host
Tomography
X-ray computed
description Abstract Objective: To describe the radiological findings in pediatric patients with hematological or oncological diseases who also have an invasive fungal infection (IFI). Materials and Methods: This was a retrospective study of all patients with IFI admitted to a pediatric hematology and oncology hospital in Brazil between 2008 and 2014. Clinical and demographic data were collected. Chest computed tomography (CT) scans of the patients were reviewed by two independent radiologists. Results: We evaluated the chest CT scans of 40 pediatric patients diagnosed with an IFI. Twenty-seven patients (67.5%) had nodules with the halo sign, seven (17.5%) had cavities, two (5.0%) had nodules without the halo sign, and seven (17.5%) had consolidation. The patients with the halo sign and cavities were older (123 vs. 77 months of age; p = 0.03) and had less severe disease (34% vs. 73%; p = 0.04). Ten patients had a proven IFI: with Aspergillus sp. (n = 4); with Candida sp. (n = 5); or with Fusarium sp. (n = 1). Conclusion: A diagnosis of IFI should be considered in children and adolescents with risk factors and abnormal CT scans, even if the imaging findings are nonspecific.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000200078
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000200078
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0100-3984.2021.0055
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
dc.source.none.fl_str_mv Radiologia Brasileira v.55 n.2 2022
reponame:Radiologia Brasileira (Online)
instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
instname_str Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron_str CBR
institution CBR
reponame_str Radiologia Brasileira (Online)
collection Radiologia Brasileira (Online)
repository.name.fl_str_mv Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
repository.mail.fl_str_mv radiologiabrasileira@cbr.org.br
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