Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2004 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/3698 |
Resumo: | Hospital Santa Izabel. Salvador, BA, Brasil. |
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Vilas-Boas, FábioFeitosa, Gilson SoaresSoares, Milena Botelho PereiraPinho Filho, Joel AlvesMota, Augusto César de AndradeAlmeida, Augusto José Gonçalves deCarvalho, Cristiane CostaCarvalho, Heitor Ghissoni deOliveira, Adriano Dourado deSantos, Ricardo Ribeiro dos2011-12-01T18:55:29Z2011-12-01T18:55:29Z2004VILAS-BOAS, F. et al. Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease. Arquivos Brasileiros de Cardiologia, v. 82, n. 2, p. 185-187, fev. 2004.0066-782Xhttps://www.arca.fiocruz.br/handle/icict/3698engBone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Hospital Santa Izabel. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.We report the first case of bone marrow cell transplantation to the myocardium of a patient with heart failure due to chagas' disease. The patient is a 52-year-old man with chronic heart failure, NYHA functional class III, despite the optimized clinical therapy. The procedure consisted of aspiration of 50 mL of bone marrow through puncture of the iliac crest, followed by filtration, separation of the mononuclear cells, resuspension, and intracoronary injection. The left ventricular ejection fraction at rest, measured using radionuclide ventriculography with labeled red blood cells prior to transplantation, was 24%, and, after 30 days, it increased to 32% with no change in the medicamentous schedule. The following measurements were assessed before and 30 days after transplantation: left ventricular end diastolic diameter (82 mm and 76 mm, respectively); Minnesota living with heart failure questionaire score (55 and 06, respectively); and distance walked in the 6-minute walking test (513 m and 683 m, respectively). Our findings show that intracoronary injection of bone marrow cells may be performed, suggesting that this is a potentially safe and effective procedure in patients with due to Chagas' disease heart failure.Transplante de Medula ÓsseaBaixo Débito CardíacoCardiomiopatia ChagásicaDoença CrônicaHumanosMasculinoMeia-IdadeMiocárdioinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALVilas-Boas F Bone marrow cell....pdfVilas-Boas F Bone marrow cell....pdfapplication/pdf79388https://www.arca.fiocruz.br/bitstream/icict/3698/1/Vilas-Boas%20F%20Bone%20marrow%20cell....pdf021c332c78dfb86abe1bd1ff7188fe86MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/3698/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTVilas-Boas F Bone marrow cell....pdf.txtVilas-Boas F Bone marrow cell....pdf.txtExtracted texttext/plain14579https://www.arca.fiocruz.br/bitstream/icict/3698/5/Vilas-Boas%20F%20Bone%20marrow%20cell....pdf.txtb5c411d908bcd73f3e469ea8775281c0MD55THUMBNAILVilas-Boas F Bone marrow cell....pdf.jpgVilas-Boas F Bone marrow cell....pdf.jpgGenerated Thumbnailimage/jpeg2210https://www.arca.fiocruz.br/bitstream/icict/3698/4/Vilas-Boas%20F%20Bone%20marrow%20cell....pdf.jpg00fd34ed1538504a8c9cc1fd804dc2ceMD54icict/36982023-03-15 14:32:58.638oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:58Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| title |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| spellingShingle |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease Vilas-Boas, Fábio Transplante de Medula Óssea Baixo Débito Cardíaco Cardiomiopatia Chagásica Doença Crônica Humanos Masculino Meia-Idade Miocárdio |
| title_short |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| title_full |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| title_fullStr |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| title_full_unstemmed |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| title_sort |
Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease |
| author |
Vilas-Boas, Fábio |
| author_facet |
Vilas-Boas, Fábio Feitosa, Gilson Soares Soares, Milena Botelho Pereira Pinho Filho, Joel Alves Mota, Augusto César de Andrade Almeida, Augusto José Gonçalves de Carvalho, Cristiane Costa Carvalho, Heitor Ghissoni de Oliveira, Adriano Dourado de Santos, Ricardo Ribeiro dos |
| author_role |
author |
| author2 |
Feitosa, Gilson Soares Soares, Milena Botelho Pereira Pinho Filho, Joel Alves Mota, Augusto César de Andrade Almeida, Augusto José Gonçalves de Carvalho, Cristiane Costa Carvalho, Heitor Ghissoni de Oliveira, Adriano Dourado de Santos, Ricardo Ribeiro dos |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Vilas-Boas, Fábio Feitosa, Gilson Soares Soares, Milena Botelho Pereira Pinho Filho, Joel Alves Mota, Augusto César de Andrade Almeida, Augusto José Gonçalves de Carvalho, Cristiane Costa Carvalho, Heitor Ghissoni de Oliveira, Adriano Dourado de Santos, Ricardo Ribeiro dos |
| dc.subject.decs.pt_BR.fl_str_mv |
Transplante de Medula Óssea Baixo Débito Cardíaco Cardiomiopatia Chagásica Doença Crônica Humanos Masculino Meia-Idade Miocárdio |
| topic |
Transplante de Medula Óssea Baixo Débito Cardíaco Cardiomiopatia Chagásica Doença Crônica Humanos Masculino Meia-Idade Miocárdio |
| description |
Hospital Santa Izabel. Salvador, BA, Brasil. |
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2004 |
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2004 |
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2011-12-01T18:55:29Z |
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2011-12-01T18:55:29Z |
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VILAS-BOAS, F. et al. Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease. Arquivos Brasileiros de Cardiologia, v. 82, n. 2, p. 185-187, fev. 2004. |
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0066-782X |
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VILAS-BOAS, F. et al. Bone marrow cell transplantation to the myocardium of a patient with heart failure due to Chagas' disease. Arquivos Brasileiros de Cardiologia, v. 82, n. 2, p. 185-187, fev. 2004. 0066-782X |
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