A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron

Detalhes bibliográficos
Autor(a) principal: LAPOLLI, ANDRE L.
Data de Publicação: 2018
Outros Autores: BARCELLOS, HENRIQUE, MATSUDA, HYLTON, SUMIYA, LUIZ C. do A., JUNQUEIRA, FERNANDO de C., INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE
Tipo de documento: Artigo de conferência
Título da fonte: Repositório Institucional do IPEN
Texto Completo: http://repositorio.ipen.br/handle/123456789/28294
Resumo: Since 2001 the Nuclear and Energy Research Institute (IPEN/CNEN-SP, Brazil) has produced about 2.5 mCi/mAh of 123I weekly using a manual irradiation system fully developed by its researchers. Ultrapure 123I has been produced and distributed to hospitals and clinics where several diagnostic imaging procedures are done for thyroid, brain and cardiovascular functions. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children. Currently IPEN researchers are involved in the development of a new fully automated irradiation system dedicated to 123I routine production employing enriched xenon gas (124Xe) as the target material. This new system consists of a target port, a water and a helium cooling system, a cryogenic system, an electric power system, a control and process monitoring unit composed of a supervisory software connected to a Programmable Logic Controller (PLC) via personal computer. In this new concept, there is no need for human interference during radioisotope production, reducing the possibility of eventual failures or incidents involving radioactive material. In this way, with this new system, a specific yield of approximately 3.5 mCi/mAh per irradiation is expected and this will meet a large part of the national demand for this important radioisotope. In the present work will be presented all the technical and constructive aspects of this new system as well as the results obtained in the irradiation of tests.
id IPEN_908d41fb990cc67d73fcee9ff2081f91
oai_identifier_str oai:repositorio.ipen.br:123456789/28294
network_acronym_str IPEN
network_name_str Repositório Institucional do IPEN
repository_id_str 4510
spelling 2018-01-11T16:50:51Z2018-01-11T16:50:51ZOctober 22-27, 2017http://repositorio.ipen.br/handle/123456789/28294Since 2001 the Nuclear and Energy Research Institute (IPEN/CNEN-SP, Brazil) has produced about 2.5 mCi/mAh of 123I weekly using a manual irradiation system fully developed by its researchers. Ultrapure 123I has been produced and distributed to hospitals and clinics where several diagnostic imaging procedures are done for thyroid, brain and cardiovascular functions. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children. Currently IPEN researchers are involved in the development of a new fully automated irradiation system dedicated to 123I routine production employing enriched xenon gas (124Xe) as the target material. This new system consists of a target port, a water and a helium cooling system, a cryogenic system, an electric power system, a control and process monitoring unit composed of a supervisory software connected to a Programmable Logic Controller (PLC) via personal computer. In this new concept, there is no need for human interference during radioisotope production, reducing the possibility of eventual failures or incidents involving radioactive material. In this way, with this new system, a specific yield of approximately 3.5 mCi/mAh per irradiation is expected and this will meet a large part of the national demand for this important radioisotope. In the present work will be presented all the technical and constructive aspects of this new system as well as the results obtained in the irradiation of tests.Submitted by Marco Antonio Oliveira da Silva (maosilva@ipen.br) on 2018-01-11T16:50:51Z No. of bitstreams: 1 24129.pdf: 1066849 bytes, checksum: 587e9702d5fef21af680e0dc5d6dcb3d (MD5)Made available in DSpace on 2018-01-11T16:50:51Z (GMT). No. of bitstreams: 1 24129.pdf: 1066849 bytes, checksum: 587e9702d5fef21af680e0dc5d6dcb3d (MD5)Associa????o Brasileira de Energia Nuclearautomationcyclotronsiodine 123irradiation devicesisotope productionperformance testingremote controlxenon 124A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotroninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectINACIRio de Janeiro, RJBelo Horizonte, MGLAPOLLI, ANDRE L.BARCELLOS, HENRIQUEMATSUDA, HYLTONSUMIYA, LUIZ C. do A.JUNQUEIRA, FERNANDO de C.INTERNATIONAL NUCLEAR ATLANTIC CONFERENCEinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional do IPENinstname:Instituto de Pesquisas Energéticas e Nucleares (IPEN)instacron:IPEN241292017LAPOLLI, ANDRE L.MATSUDA, HYLTONSUMIYA, LUIZ C. do A.JUNQUEIRA, FERNANDO de C.BARCELLOS, HENRIQUE18-01Proceedings1541141701283430LAPOLLI, ANDRE L.:154:110:SBARCELLOS, HENRIQUE:1141:110:NMATSUDA, HYLTON:701:110:NSUMIYA, LUIZ C. DO A.:283:110:NJUNQUEIRA, FERNANDO DE C.:430:420:NORIGINAL24129.pdf24129.pdfapplication/pdf1066849http://repositorio.ipen.br/bitstream/123456789/28294/1/24129.pdf587e9702d5fef21af680e0dc5d6dcb3dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ipen.br/bitstream/123456789/28294/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/282942022-03-23 18:09:08.715oai:repositorio.ipen.br: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Repositório InstitucionalPUBhttp://repositorio.ipen.br/oai/requestbibl@ipen.bropendoar:45102022-03-23T18:09:08Repositório Institucional do IPEN - Instituto de Pesquisas Energéticas e Nucleares (IPEN)false
dc.title.pt_BR.fl_str_mv A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
title A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
spellingShingle A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
LAPOLLI, ANDRE L.
automation
cyclotrons
iodine 123
irradiation devices
isotope production
performance testing
remote control
xenon 124
title_short A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
title_full A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
title_fullStr A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
title_full_unstemmed A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
title_sort A new 124Xe irradiation system for 123I routine production at the 30 MeV IPEN-CNEN/SP cyclotron
author LAPOLLI, ANDRE L.
author_facet LAPOLLI, ANDRE L.
BARCELLOS, HENRIQUE
MATSUDA, HYLTON
SUMIYA, LUIZ C. do A.
JUNQUEIRA, FERNANDO de C.
INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE
author_role author
author2 BARCELLOS, HENRIQUE
MATSUDA, HYLTON
SUMIYA, LUIZ C. do A.
JUNQUEIRA, FERNANDO de C.
INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv LAPOLLI, ANDRE L.
BARCELLOS, HENRIQUE
MATSUDA, HYLTON
SUMIYA, LUIZ C. do A.
JUNQUEIRA, FERNANDO de C.
INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE
dc.subject.por.fl_str_mv automation
cyclotrons
iodine 123
irradiation devices
isotope production
performance testing
remote control
xenon 124
topic automation
cyclotrons
iodine 123
irradiation devices
isotope production
performance testing
remote control
xenon 124
description Since 2001 the Nuclear and Energy Research Institute (IPEN/CNEN-SP, Brazil) has produced about 2.5 mCi/mAh of 123I weekly using a manual irradiation system fully developed by its researchers. Ultrapure 123I has been produced and distributed to hospitals and clinics where several diagnostic imaging procedures are done for thyroid, brain and cardiovascular functions. Due to the short half-life and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in children. Currently IPEN researchers are involved in the development of a new fully automated irradiation system dedicated to 123I routine production employing enriched xenon gas (124Xe) as the target material. This new system consists of a target port, a water and a helium cooling system, a cryogenic system, an electric power system, a control and process monitoring unit composed of a supervisory software connected to a Programmable Logic Controller (PLC) via personal computer. In this new concept, there is no need for human interference during radioisotope production, reducing the possibility of eventual failures or incidents involving radioactive material. In this way, with this new system, a specific yield of approximately 3.5 mCi/mAh per irradiation is expected and this will meet a large part of the national demand for this important radioisotope. In the present work will be presented all the technical and constructive aspects of this new system as well as the results obtained in the irradiation of tests.
publishDate 2018
dc.date.evento.pt_BR.fl_str_mv October 22-27, 2017
dc.date.accessioned.fl_str_mv 2018-01-11T16:50:51Z
dc.date.available.fl_str_mv 2018-01-11T16:50:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ipen.br/handle/123456789/28294
url http://repositorio.ipen.br/handle/123456789/28294
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.coverage.pt_BR.fl_str_mv I
dc.publisher.none.fl_str_mv Associa????o Brasileira de Energia Nuclear
publisher.none.fl_str_mv Associa????o Brasileira de Energia Nuclear
dc.source.none.fl_str_mv reponame:Repositório Institucional do IPEN
instname:Instituto de Pesquisas Energéticas e Nucleares (IPEN)
instacron:IPEN
instname_str Instituto de Pesquisas Energéticas e Nucleares (IPEN)
instacron_str IPEN
institution IPEN
reponame_str Repositório Institucional do IPEN
collection Repositório Institucional do IPEN
bitstream.url.fl_str_mv http://repositorio.ipen.br/bitstream/123456789/28294/1/24129.pdf
http://repositorio.ipen.br/bitstream/123456789/28294/2/license.txt
bitstream.checksum.fl_str_mv 587e9702d5fef21af680e0dc5d6dcb3d
8a4605be74aa9ea9d79846c1fba20a33
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional do IPEN - Instituto de Pesquisas Energéticas e Nucleares (IPEN)
repository.mail.fl_str_mv bibl@ipen.br
_version_ 1767254243716104192

Registros relacionados