Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses

Detalhes bibliográficos
Autor(a) principal: González-Méijome, José Manuel
Data de Publicação: 2009
Outros Autores: López-Alemany, António, Almeida, José B., Parafita, Manuel A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/8565
Resumo: Abstract: Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated withAFM over a surface of 25 lm2 according to previously published experimental setup. Average roughness (Ra) and root mean square (Rms) values were obtained for unworn and worn samples. Results. The Ra value increased for balafilcon A (11.62–13.68 nm for unworn and worn samples, respectively), lotrafilcon A (3.67–15.01 nm for unworn and worn samples, respectively), lotrafilcon B (4.08–8.42 nm for unworn and worn samples, respectively), galyfilcon A (2.81–14.6 nm for unworn and worn samples, respectively), and comfilcon A (2.87–4.63 nm for unworn and worn samples, respectively). Differences were statistically significant for all lenses except Rms and Ra for comfilcon A, and Ra parameter for balafilcon A (p > 0.05). The least relative increase was observed for some balafilcon A samples and for some of these samples the roughness decreased after the lenses had been worn. Conclusion. The changes in surface roughness between unworn and worn lenses are different for different silicone-hydrogel materials. Overall all CLs increased the degree of surface roughness after being worn, even for very short periods of time. However, for samples of balafilcon A, roughness increases at a lower extent or even can decrease as compared to unworn samples of the same material due to filling of the macropores.
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spelling Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lensesAtomic force microscopyContact lensPolymer deteriorationSurface characterizationdegradationwearScience & TechnologyAbstract: Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated withAFM over a surface of 25 lm2 according to previously published experimental setup. Average roughness (Ra) and root mean square (Rms) values were obtained for unworn and worn samples. Results. The Ra value increased for balafilcon A (11.62–13.68 nm for unworn and worn samples, respectively), lotrafilcon A (3.67–15.01 nm for unworn and worn samples, respectively), lotrafilcon B (4.08–8.42 nm for unworn and worn samples, respectively), galyfilcon A (2.81–14.6 nm for unworn and worn samples, respectively), and comfilcon A (2.87–4.63 nm for unworn and worn samples, respectively). Differences were statistically significant for all lenses except Rms and Ra for comfilcon A, and Ra parameter for balafilcon A (p > 0.05). The least relative increase was observed for some balafilcon A samples and for some of these samples the roughness decreased after the lenses had been worn. Conclusion. The changes in surface roughness between unworn and worn lenses are different for different silicone-hydrogel materials. Overall all CLs increased the degree of surface roughness after being worn, even for very short periods of time. However, for samples of balafilcon A, roughness increases at a lower extent or even can decrease as compared to unworn samples of the same material due to filling of the macropores.Fundação para a Ciência e a Tecnologia (FCT)Ministério da Ciência e Ensino Superior (MCES)Fundo Social Europeu - contrato nº 8281/2002.WileyUniversidade do MinhoGonzález-Méijome, José ManuelLópez-Alemany, AntónioAlmeida, José B.Parafita, Manuel A.2009-012009-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/8565eng"Journal of Biomedical Materials Research : applied biomaterials". ISSN 1552-4973. 88B:1 (Jan. 2009) 75-82.1552-497310.1002/jbm.b.3115318618476http://www3.interscience.wiley.com/info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:30:34Zoai:repositorium.sdum.uminho.pt:1822/8565Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:25:47.933534Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
title Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
spellingShingle Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
González-Méijome, José Manuel
Atomic force microscopy
Contact lens
Polymer deterioration
Surface characterization
degradation
wear
Science & Technology
title_short Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
title_full Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
title_fullStr Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
title_full_unstemmed Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
title_sort Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact lenses
author González-Méijome, José Manuel
author_facet González-Méijome, José Manuel
López-Alemany, António
Almeida, José B.
Parafita, Manuel A.
author_role author
author2 López-Alemany, António
Almeida, José B.
Parafita, Manuel A.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv González-Méijome, José Manuel
López-Alemany, António
Almeida, José B.
Parafita, Manuel A.
dc.subject.por.fl_str_mv Atomic force microscopy
Contact lens
Polymer deterioration
Surface characterization
degradation
wear
Science & Technology
topic Atomic force microscopy
Contact lens
Polymer deterioration
Surface characterization
degradation
wear
Science & Technology
description Abstract: Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated withAFM over a surface of 25 lm2 according to previously published experimental setup. Average roughness (Ra) and root mean square (Rms) values were obtained for unworn and worn samples. Results. The Ra value increased for balafilcon A (11.62–13.68 nm for unworn and worn samples, respectively), lotrafilcon A (3.67–15.01 nm for unworn and worn samples, respectively), lotrafilcon B (4.08–8.42 nm for unworn and worn samples, respectively), galyfilcon A (2.81–14.6 nm for unworn and worn samples, respectively), and comfilcon A (2.87–4.63 nm for unworn and worn samples, respectively). Differences were statistically significant for all lenses except Rms and Ra for comfilcon A, and Ra parameter for balafilcon A (p > 0.05). The least relative increase was observed for some balafilcon A samples and for some of these samples the roughness decreased after the lenses had been worn. Conclusion. The changes in surface roughness between unworn and worn lenses are different for different silicone-hydrogel materials. Overall all CLs increased the degree of surface roughness after being worn, even for very short periods of time. However, for samples of balafilcon A, roughness increases at a lower extent or even can decrease as compared to unworn samples of the same material due to filling of the macropores.
publishDate 2009
dc.date.none.fl_str_mv 2009-01
2009-01-01T00:00:00Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/8565
url https://hdl.handle.net/1822/8565
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv "Journal of Biomedical Materials Research : applied biomaterials". ISSN 1552-4973. 88B:1 (Jan. 2009) 75-82.
1552-4973
10.1002/jbm.b.31153
18618476
http://www3.interscience.wiley.com/
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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