Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation

Detalhes bibliográficos
Autor(a) principal: Dias, João Lopes
Data de Publicação: 2015
Outros Autores: Cunha, Teresa Margarida, Gomes, Filipe Veloso, Callé, Catarina, Félix, Ana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/14926
Resumo: Background Both primary and secondary gynaecological neuroendocrine (NE) tumours are uncommon, and the literature is scarce concerning their imaging features. Methods This article reviews the epidemiological, clinical and imaging features with pathological correlation of gynaecological NE tumours. Results The clinical features of gynaecological NE tumours are non-specific and depend on the organ of origin and on the extension and aggressiveness of the disease. The imaging approach to these tumours is similar to that for other histological types and the Revised International Federation of Gynecology and Obstetrics (FIGO) Staging System also applies to NE tumours. Neuroendocrine tumours were recently divided into two groups: poorly differentiated neuroendocrine carcinomas (NECs) and well-differentiated neuroendocrine tumours (NETs). NECs include small cell carcinoma and large cell neuroendocrine carcinoma, while NETs account for typical and atypical carcinoids. Cervical small cell carcinoma and ovarian carcinoid are the most common gynaecological NE tumours. The former typically behaves aggressively; the latter usually behaves in a benign fashion and tends to be confined to the organ. Conclusion While dealing with ovarian carcinoids, extraovarian extension, bilaterality and multinodularity raise the suspicion of metastatic disease. NE tumours of the endometrium and other gynaecological locations are very rare. Teaching Points • Primary or secondary neurondocrine (NE) tumours of the female genital tract are rare. • Cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological NE tumours. • Cervical small cell carcinomas usually behave aggressively. • Ovarian carcinoids tend to behave in a benign fashion. • The imaging approach to gynaecological NE tumours and other histological types is similar.
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spelling Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlationPoorly differentiated neuroendocrine carcinomas (NECs)Well-differentiated neuroendocrine tumours (NETs)Small cell carcinomaLarge cell neuroendocrine carcinomaCarcinoidBackground Both primary and secondary gynaecological neuroendocrine (NE) tumours are uncommon, and the literature is scarce concerning their imaging features. Methods This article reviews the epidemiological, clinical and imaging features with pathological correlation of gynaecological NE tumours. Results The clinical features of gynaecological NE tumours are non-specific and depend on the organ of origin and on the extension and aggressiveness of the disease. The imaging approach to these tumours is similar to that for other histological types and the Revised International Federation of Gynecology and Obstetrics (FIGO) Staging System also applies to NE tumours. Neuroendocrine tumours were recently divided into two groups: poorly differentiated neuroendocrine carcinomas (NECs) and well-differentiated neuroendocrine tumours (NETs). NECs include small cell carcinoma and large cell neuroendocrine carcinoma, while NETs account for typical and atypical carcinoids. Cervical small cell carcinoma and ovarian carcinoid are the most common gynaecological NE tumours. The former typically behaves aggressively; the latter usually behaves in a benign fashion and tends to be confined to the organ. Conclusion While dealing with ovarian carcinoids, extraovarian extension, bilaterality and multinodularity raise the suspicion of metastatic disease. NE tumours of the endometrium and other gynaecological locations are very rare. Teaching Points • Primary or secondary neurondocrine (NE) tumours of the female genital tract are rare. • Cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological NE tumours. • Cervical small cell carcinomas usually behave aggressively. • Ovarian carcinoids tend to behave in a benign fashion. • The imaging approach to gynaecological NE tumours and other histological types is similar.SpringerRepositório ComumDias, João LopesCunha, Teresa MargaridaGomes, Filipe VelosoCallé, CatarinaFélix, Ana2016-09-30T15:32:03Z20152016-07-23T10:07:12Z2015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/14926engJoão Lopes Dias; Teresa Margarida Cunha; Filipe Veloso Gomes; Catarina Callé; Ana Félix. Neuroendocrine Tumours of the Female Genital Tract: a Case-based Imaging Review with Pathological Correlation , Insights into Imaging, 6, 1, 43-52, 2015.1869-410110.1007/s13244-014-0378-5info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T06:46:17Zoai:comum.rcaap.pt:10400.26/14926Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:36:13.614673Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
title Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
spellingShingle Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
Dias, João Lopes
Poorly differentiated neuroendocrine carcinomas (NECs)
Well-differentiated neuroendocrine tumours (NETs)
Small cell carcinoma
Large cell neuroendocrine carcinoma
Carcinoid
title_short Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
title_full Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
title_fullStr Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
title_full_unstemmed Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
title_sort Neuroendocrine tumours of the female genital tract: a case-based imaging review with pathological correlation
author Dias, João Lopes
author_facet Dias, João Lopes
Cunha, Teresa Margarida
Gomes, Filipe Veloso
Callé, Catarina
Félix, Ana
author_role author
author2 Cunha, Teresa Margarida
Gomes, Filipe Veloso
Callé, Catarina
Félix, Ana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Dias, João Lopes
Cunha, Teresa Margarida
Gomes, Filipe Veloso
Callé, Catarina
Félix, Ana
dc.subject.por.fl_str_mv Poorly differentiated neuroendocrine carcinomas (NECs)
Well-differentiated neuroendocrine tumours (NETs)
Small cell carcinoma
Large cell neuroendocrine carcinoma
Carcinoid
topic Poorly differentiated neuroendocrine carcinomas (NECs)
Well-differentiated neuroendocrine tumours (NETs)
Small cell carcinoma
Large cell neuroendocrine carcinoma
Carcinoid
description Background Both primary and secondary gynaecological neuroendocrine (NE) tumours are uncommon, and the literature is scarce concerning their imaging features. Methods This article reviews the epidemiological, clinical and imaging features with pathological correlation of gynaecological NE tumours. Results The clinical features of gynaecological NE tumours are non-specific and depend on the organ of origin and on the extension and aggressiveness of the disease. The imaging approach to these tumours is similar to that for other histological types and the Revised International Federation of Gynecology and Obstetrics (FIGO) Staging System also applies to NE tumours. Neuroendocrine tumours were recently divided into two groups: poorly differentiated neuroendocrine carcinomas (NECs) and well-differentiated neuroendocrine tumours (NETs). NECs include small cell carcinoma and large cell neuroendocrine carcinoma, while NETs account for typical and atypical carcinoids. Cervical small cell carcinoma and ovarian carcinoid are the most common gynaecological NE tumours. The former typically behaves aggressively; the latter usually behaves in a benign fashion and tends to be confined to the organ. Conclusion While dealing with ovarian carcinoids, extraovarian extension, bilaterality and multinodularity raise the suspicion of metastatic disease. NE tumours of the endometrium and other gynaecological locations are very rare. Teaching Points • Primary or secondary neurondocrine (NE) tumours of the female genital tract are rare. • Cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological NE tumours. • Cervical small cell carcinomas usually behave aggressively. • Ovarian carcinoids tend to behave in a benign fashion. • The imaging approach to gynaecological NE tumours and other histological types is similar.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2016-09-30T15:32:03Z
2016-07-23T10:07:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/14926
url http://hdl.handle.net/10400.26/14926
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv João Lopes Dias; Teresa Margarida Cunha; Filipe Veloso Gomes; Catarina Callé; Ana Félix. Neuroendocrine Tumours of the Female Genital Tract: a Case-based Imaging Review with Pathological Correlation , Insights into Imaging, 6, 1, 43-52, 2015.
1869-4101
10.1007/s13244-014-0378-5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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