A mathematical model of controlled drug release in a completely detached vitreous

Detalhes bibliográficos
Autor(a) principal: Ferreira, José Augusto
Data de Publicação: 2015
Outros Autores: Oliveira, Paula de, Silva, Pascoal, Silva, Rufino
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/44957
Resumo: A model represented by four coupled systems of partial differential equations describing the transport of drug in the posterior segment of the eye is presented. The case of drug release to the retina through an aging eye and where a vitreous chamber detachment has already occurred is analyzed. Numerical simulations lead to a better understanding of in vitro results and suggest new research paths.