Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Cardiovascular Surgery (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300013 |
Resumo: | OBJECTIVE: The aim of this study is to evaluate the applicability of a new score for predicting mediastinitis - MagedanzSCORE - in patients undergoing coronary artery bypass graft (CABG) surgery in the Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco - PROCAPE. METHODS: Retrospective study involving 500 patients operated between May/2007 and April/2010. The registers contained all the information used to calculate the MagedanzSCORE. The outcome of interest was mediastinitis. We calculated sensitivity, specificity, positive predictive value, negative predictive value, concordance and accuracy. The accuracy of the model was evaluated by ROC (receiver operating characteristic) curve. RESULTS: The incidence of mediastinitis was 5.6%, with a lethality rate of 32.1%. In univariate analysis, the five variables of the MagedanzSCORE were predictors of postoperative mediastinitis: chronic obstructive pulmonary disease (OR 6.42; 95.0% CI 2.76-14.96; P<0.001), obesity (OR 3.06; 95.0% CI 1.32-7.09; P=0.009), surgical reintervention (OR 82.40; 95.0% CI 30.40-223.30; P<0.001), multiple transfusion (OR 3.33; 95.0% CI 1.52-7.29; P=0.003) and stable angina class IV or unstable (OR 2.59; 95.0% CI 1.19-7.64; P=0.016) according to Canadian Cardiovascular Society. The score had a sensitivity of 96.4%, specificity of 90.0%, positive predictive value of 36.5%, negative predictive value of 99.8% and 90.4% concordance. The accuracy measured by the area under the ROC curve was 96.2% (95.0% CI 94.5%-97.9%). CONCLUSIONS: The MagedanzSCORE proved to be a simple and objective index, revealing a satisfactory predictor of development of postoperative mediastinitis in patients undergoing CABG surgery at our institution |
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Brazilian Journal of Cardiovascular Surgery (Online) |
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Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgeryRisk factorsMediastinitisCoronary artery bypassMyocardial revascularizationOBJECTIVE: The aim of this study is to evaluate the applicability of a new score for predicting mediastinitis - MagedanzSCORE - in patients undergoing coronary artery bypass graft (CABG) surgery in the Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco - PROCAPE. METHODS: Retrospective study involving 500 patients operated between May/2007 and April/2010. The registers contained all the information used to calculate the MagedanzSCORE. The outcome of interest was mediastinitis. We calculated sensitivity, specificity, positive predictive value, negative predictive value, concordance and accuracy. The accuracy of the model was evaluated by ROC (receiver operating characteristic) curve. RESULTS: The incidence of mediastinitis was 5.6%, with a lethality rate of 32.1%. In univariate analysis, the five variables of the MagedanzSCORE were predictors of postoperative mediastinitis: chronic obstructive pulmonary disease (OR 6.42; 95.0% CI 2.76-14.96; P<0.001), obesity (OR 3.06; 95.0% CI 1.32-7.09; P=0.009), surgical reintervention (OR 82.40; 95.0% CI 30.40-223.30; P<0.001), multiple transfusion (OR 3.33; 95.0% CI 1.52-7.29; P=0.003) and stable angina class IV or unstable (OR 2.59; 95.0% CI 1.19-7.64; P=0.016) according to Canadian Cardiovascular Society. The score had a sensitivity of 96.4%, specificity of 90.0%, positive predictive value of 36.5%, negative predictive value of 99.8% and 90.4% concordance. The accuracy measured by the area under the ROC curve was 96.2% (95.0% CI 94.5%-97.9%). CONCLUSIONS: The MagedanzSCORE proved to be a simple and objective index, revealing a satisfactory predictor of development of postoperative mediastinitis in patients undergoing CABG surgery at our institutionSociedade Brasileira de Cirurgia Cardiovascular2011-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300013Brazilian Journal of Cardiovascular Surgery v.26 n.3 2011reponame:Brazilian Journal of Cardiovascular Surgery (Online)instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)instacron:SBCCV10.5935/1678-9741.20110013info:eu-repo/semantics/openAccessSá,Michel Pompeu Barros de OliveiraFigueira,Evelyn SoaresSantos,Cecília AndradeFigueiredo,Omar JacobinaLima,Renato Oliveira AlbuquerqueRueda,Fábio Gonçalves deEscobar,Rodrigo Renda deSoares,Alexandre Magno Macário NunesLima,Ricardo de Carvalhoeng2011-12-15T00:00:00Zoai:scielo:S0102-76382011000300013Revistahttp://www.rbccv.org.br/https://old.scielo.br/oai/scielo-oai.php||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br1678-97410102-7638opendoar:2011-12-15T00:00Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)false |
dc.title.none.fl_str_mv |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
title |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
spellingShingle |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery Sá,Michel Pompeu Barros de Oliveira Risk factors Mediastinitis Coronary artery bypass Myocardial revascularization |
title_short |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
title_full |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
title_fullStr |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
title_full_unstemmed |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
title_sort |
Validation of MagedanzSCORE as a predictor of mediastinitis after coronary artery bypass graft surgery |
author |
Sá,Michel Pompeu Barros de Oliveira |
author_facet |
Sá,Michel Pompeu Barros de Oliveira Figueira,Evelyn Soares Santos,Cecília Andrade Figueiredo,Omar Jacobina Lima,Renato Oliveira Albuquerque Rueda,Fábio Gonçalves de Escobar,Rodrigo Renda de Soares,Alexandre Magno Macário Nunes Lima,Ricardo de Carvalho |
author_role |
author |
author2 |
Figueira,Evelyn Soares Santos,Cecília Andrade Figueiredo,Omar Jacobina Lima,Renato Oliveira Albuquerque Rueda,Fábio Gonçalves de Escobar,Rodrigo Renda de Soares,Alexandre Magno Macário Nunes Lima,Ricardo de Carvalho |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sá,Michel Pompeu Barros de Oliveira Figueira,Evelyn Soares Santos,Cecília Andrade Figueiredo,Omar Jacobina Lima,Renato Oliveira Albuquerque Rueda,Fábio Gonçalves de Escobar,Rodrigo Renda de Soares,Alexandre Magno Macário Nunes Lima,Ricardo de Carvalho |
dc.subject.por.fl_str_mv |
Risk factors Mediastinitis Coronary artery bypass Myocardial revascularization |
topic |
Risk factors Mediastinitis Coronary artery bypass Myocardial revascularization |
description |
OBJECTIVE: The aim of this study is to evaluate the applicability of a new score for predicting mediastinitis - MagedanzSCORE - in patients undergoing coronary artery bypass graft (CABG) surgery in the Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco - PROCAPE. METHODS: Retrospective study involving 500 patients operated between May/2007 and April/2010. The registers contained all the information used to calculate the MagedanzSCORE. The outcome of interest was mediastinitis. We calculated sensitivity, specificity, positive predictive value, negative predictive value, concordance and accuracy. The accuracy of the model was evaluated by ROC (receiver operating characteristic) curve. RESULTS: The incidence of mediastinitis was 5.6%, with a lethality rate of 32.1%. In univariate analysis, the five variables of the MagedanzSCORE were predictors of postoperative mediastinitis: chronic obstructive pulmonary disease (OR 6.42; 95.0% CI 2.76-14.96; P<0.001), obesity (OR 3.06; 95.0% CI 1.32-7.09; P=0.009), surgical reintervention (OR 82.40; 95.0% CI 30.40-223.30; P<0.001), multiple transfusion (OR 3.33; 95.0% CI 1.52-7.29; P=0.003) and stable angina class IV or unstable (OR 2.59; 95.0% CI 1.19-7.64; P=0.016) according to Canadian Cardiovascular Society. The score had a sensitivity of 96.4%, specificity of 90.0%, positive predictive value of 36.5%, negative predictive value of 99.8% and 90.4% concordance. The accuracy measured by the area under the ROC curve was 96.2% (95.0% CI 94.5%-97.9%). CONCLUSIONS: The MagedanzSCORE proved to be a simple and objective index, revealing a satisfactory predictor of development of postoperative mediastinitis in patients undergoing CABG surgery at our institution |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300013 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382011000300013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/1678-9741.20110013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cirurgia Cardiovascular |
dc.source.none.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery v.26 n.3 2011 reponame:Brazilian Journal of Cardiovascular Surgery (Online) instname:Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV |
instname_str |
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
instacron_str |
SBCCV |
institution |
SBCCV |
reponame_str |
Brazilian Journal of Cardiovascular Surgery (Online) |
collection |
Brazilian Journal of Cardiovascular Surgery (Online) |
repository.name.fl_str_mv |
Brazilian Journal of Cardiovascular Surgery (Online) - Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) |
repository.mail.fl_str_mv |
||rosangela.monteiro@incor.usp.br|| domingo@braile.com.br|| brandau@braile.com.br |
_version_ |
1752126597597495296 |