Association between vitamin d levels and adolescent idiopathic scoliosis
Main Author: | |
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Publication Date: | 2014 |
Other Authors: | , , , , , |
Format: | Article |
Language: | eng |
Source: | Coluna/Columna |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-18512014000400275 |
Summary: | Objective: To compare the levels of 25-hydroxyvitamin D in patients with AIS and a control group. Methods: The patients were recruited from the outpatient clinic of our institution during the year of 2013. Children diagnosed with scoliosis before 10 or after 18 years of age, and those suffering from neurological or muscular disorders, congenital malformations or genetic syndromes were excluded. The 25-OHD levels were determined by a fully automated electrochemiluminescence test. The appropriate level of 25-OHD was defined as greater than 30 ng/mL. The results were compared to a group of healthy individuals. Results: In group 1 (control) 63,3% showed abnormal vitamin D levels, while 91% of patients with AIS presented a low level of vitamin D. The mean BMI was 19.6 kg/m2 for controls and 20.3 kg/m2 for group 2. Statistical analysis showed significant difference (p<0.0001) between the levels of vitamin D. The average and minimum levels of vitamin D were respectively 27 and 13.6 ng/mL for group 1 and 18.8 and 3.13 ng/mL for AIS group. Conclusions: Patients with AIS had statistically significant lower levels of 25-OHD than healthy patients. Further research should be conducted to investigate the actual impact of serum vitamin D levels on the pathophysiology of AIS. |
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Association between vitamin d levels and adolescent idiopathic scoliosis Objective: To compare the levels of 25-hydroxyvitamin D in patients with AIS and a control group. Methods: The patients were recruited from the outpatient clinic of our institution during the year of 2013. Children diagnosed with scoliosis before 10 or after 18 years of age, and those suffering from neurological or muscular disorders, congenital malformations or genetic syndromes were excluded. The 25-OHD levels were determined by a fully automated electrochemiluminescence test. The appropriate level of 25-OHD was defined as greater than 30 ng/mL. The results were compared to a group of healthy individuals. Results: In group 1 (control) 63,3% showed abnormal vitamin D levels, while 91% of patients with AIS presented a low level of vitamin D. The mean BMI was 19.6 kg/m2 for controls and 20.3 kg/m2 for group 2. Statistical analysis showed significant difference (p<0.0001) between the levels of vitamin D. The average and minimum levels of vitamin D were respectively 27 and 13.6 ng/mL for group 1 and 18.8 and 3.13 ng/mL for AIS group. Conclusions: Patients with AIS had statistically significant lower levels of 25-OHD than healthy patients. Further research should be conducted to investigate the actual impact of serum vitamin D levels on the pathophysiology of AIS. Sociedade Brasileira de Coluna2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-18512014000400275Coluna/Columna v.13 n.4 2014reponame:Coluna/Columnainstname:Sociedade Brasileira de Coluna (SBCO)instacron:SBCO10.1590/S1808-18512014130400432info:eu-repo/semantics/openAccessBatista,Rodrigo Martins Borges FerreiraMartins,Délio EulálioWajchenberg,MarceloLazaretti,MarisePuertas,Eduardo BarrosTerreri,Maria Teresa de Sande e Lemos Ramos AscensãoHayashi,Lilian Fukusimaeng2015-01-16T00:00:00Zoai:scielo:S1808-18512014000400275Revistahttps://www.revistacoluna.org/ONGhttps://old.scielo.br/oai/scielo-oai.phpcoluna.columna@uol.com.br||revistacoluna@uol.com.br2177-014X1808-1851opendoar:2015-01-16T00:00Coluna/Columna - Sociedade Brasileira de Coluna (SBCO)false |
dc.title.none.fl_str_mv |
Association between vitamin d levels and adolescent idiopathic scoliosis |
title |
Association between vitamin d levels and adolescent idiopathic scoliosis |
spellingShingle |
Association between vitamin d levels and adolescent idiopathic scoliosis Batista,Rodrigo Martins Borges Ferreira |
title_short |
Association between vitamin d levels and adolescent idiopathic scoliosis |
title_full |
Association between vitamin d levels and adolescent idiopathic scoliosis |
title_fullStr |
Association between vitamin d levels and adolescent idiopathic scoliosis |
title_full_unstemmed |
Association between vitamin d levels and adolescent idiopathic scoliosis |
title_sort |
Association between vitamin d levels and adolescent idiopathic scoliosis |
author |
Batista,Rodrigo Martins Borges Ferreira |
author_facet |
Batista,Rodrigo Martins Borges Ferreira Martins,Délio Eulálio Wajchenberg,Marcelo Lazaretti,Marise Puertas,Eduardo Barros Terreri,Maria Teresa de Sande e Lemos Ramos Ascensão Hayashi,Lilian Fukusima |
author_role |
author |
author2 |
Martins,Délio Eulálio Wajchenberg,Marcelo Lazaretti,Marise Puertas,Eduardo Barros Terreri,Maria Teresa de Sande e Lemos Ramos Ascensão Hayashi,Lilian Fukusima |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Batista,Rodrigo Martins Borges Ferreira Martins,Délio Eulálio Wajchenberg,Marcelo Lazaretti,Marise Puertas,Eduardo Barros Terreri,Maria Teresa de Sande e Lemos Ramos Ascensão Hayashi,Lilian Fukusima |
description |
Objective: To compare the levels of 25-hydroxyvitamin D in patients with AIS and a control group. Methods: The patients were recruited from the outpatient clinic of our institution during the year of 2013. Children diagnosed with scoliosis before 10 or after 18 years of age, and those suffering from neurological or muscular disorders, congenital malformations or genetic syndromes were excluded. The 25-OHD levels were determined by a fully automated electrochemiluminescence test. The appropriate level of 25-OHD was defined as greater than 30 ng/mL. The results were compared to a group of healthy individuals. Results: In group 1 (control) 63,3% showed abnormal vitamin D levels, while 91% of patients with AIS presented a low level of vitamin D. The mean BMI was 19.6 kg/m2 for controls and 20.3 kg/m2 for group 2. Statistical analysis showed significant difference (p<0.0001) between the levels of vitamin D. The average and minimum levels of vitamin D were respectively 27 and 13.6 ng/mL for group 1 and 18.8 and 3.13 ng/mL for AIS group. Conclusions: Patients with AIS had statistically significant lower levels of 25-OHD than healthy patients. Further research should be conducted to investigate the actual impact of serum vitamin D levels on the pathophysiology of AIS. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-18512014000400275 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-18512014000400275 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1808-18512014130400432 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Coluna |
publisher.none.fl_str_mv |
Sociedade Brasileira de Coluna |
dc.source.none.fl_str_mv |
Coluna/Columna v.13 n.4 2014 reponame:Coluna/Columna instname:Sociedade Brasileira de Coluna (SBCO) instacron:SBCO |
instname_str |
Sociedade Brasileira de Coluna (SBCO) |
instacron_str |
SBCO |
institution |
SBCO |
reponame_str |
Coluna/Columna |
collection |
Coluna/Columna |
repository.name.fl_str_mv |
Coluna/Columna - Sociedade Brasileira de Coluna (SBCO) |
repository.mail.fl_str_mv |
coluna.columna@uol.com.br||revistacoluna@uol.com.br |
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1752126614736470016 |