Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa

Detalhes bibliográficos
Autor(a) principal: Dias, Antônio Santos
Data de Publicação: 2013
Outros Autores: Silva, Déborah Soares Bispo Santos, Barboza, Benhur, Garcia, Anuska Conde Fagundes Soares, Oliveira, Betejane de, Estevam, Charles dos Santos, Araújo Neto, Vitor, Santos, André Luiz Lima Menezes dos, Scher, Ricardo, Pantaleao, Silmara de Moraes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/1415
Resumo: Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.
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spelling Dias, Antônio SantosSilva, Déborah Soares Bispo SantosBarboza, BenhurGarcia, Anuska Conde Fagundes SoaresOliveira, Betejane deEstevam, Charles dos SantosAraújo Neto, VitorSantos, André Luiz Lima Menezes dosScher, RicardoPantaleao, Silmara de Moraes2015-01-29T21:25:36Z2015-01-29T21:25:36Z2013-04SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015.0102-695Xhttps://ri.ufs.br/handle/riufs/1415Creative Commons Attribution LicenseErythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.Sociedade Brasileira de FarmacognosiaAnsiedadeAgitaçãoInsôniaErythrina velutina WilldInvestigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILInvestigationOfProtective.pdf.jpgInvestigationOfProtective.pdf.jpgGenerated Thumbnailimage/jpeg1663https://ri.ufs.br/jspui/bitstream/riufs/1415/4/InvestigationOfProtective.pdf.jpg6ef0ae95cd083732b0362f7247fa1924MD54ORIGINALInvestigationOfProtective.pdfInvestigationOfProtective.pdfapplication/pdf893047https://ri.ufs.br/jspui/bitstream/riufs/1415/1/InvestigationOfProtective.pdfb7029bccc89009fa82298123910ea539MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1415/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTInvestigationOfProtective.pdf.txtInvestigationOfProtective.pdf.txtExtracted texttext/plain26342https://ri.ufs.br/jspui/bitstream/riufs/1415/3/InvestigationOfProtective.pdf.txt27e4063a8cfb196890a849fb3a171dddMD53riufs/14152016-03-14 11:34:01.093oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2016-03-14T14:34:01Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
title Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
spellingShingle Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
Dias, Antônio Santos
Ansiedade
Agitação
Insônia
Erythrina velutina Willd
title_short Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
title_full Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
title_fullStr Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
title_full_unstemmed Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
title_sort Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
author Dias, Antônio Santos
author_facet Dias, Antônio Santos
Silva, Déborah Soares Bispo Santos
Barboza, Benhur
Garcia, Anuska Conde Fagundes Soares
Oliveira, Betejane de
Estevam, Charles dos Santos
Araújo Neto, Vitor
Santos, André Luiz Lima Menezes dos
Scher, Ricardo
Pantaleao, Silmara de Moraes
author_role author
author2 Silva, Déborah Soares Bispo Santos
Barboza, Benhur
Garcia, Anuska Conde Fagundes Soares
Oliveira, Betejane de
Estevam, Charles dos Santos
Araújo Neto, Vitor
Santos, André Luiz Lima Menezes dos
Scher, Ricardo
Pantaleao, Silmara de Moraes
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Dias, Antônio Santos
Silva, Déborah Soares Bispo Santos
Barboza, Benhur
Garcia, Anuska Conde Fagundes Soares
Oliveira, Betejane de
Estevam, Charles dos Santos
Araújo Neto, Vitor
Santos, André Luiz Lima Menezes dos
Scher, Ricardo
Pantaleao, Silmara de Moraes
dc.subject.por.fl_str_mv Ansiedade
Agitação
Insônia
Erythrina velutina Willd
topic Ansiedade
Agitação
Insônia
Erythrina velutina Willd
description Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.
publishDate 2013
dc.date.issued.fl_str_mv 2013-04
dc.date.accessioned.fl_str_mv 2015-01-29T21:25:36Z
dc.date.available.fl_str_mv 2015-01-29T21:25:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/1415
dc.identifier.issn.none.fl_str_mv 0102-695X
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Attribution License
identifier_str_mv SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015.
0102-695X
Creative Commons Attribution License
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
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reponame_str Repositório Institucional da UFS
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