Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/1415 |
Resumo: | Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential. |
id |
UFS-2_93555046cf6554590a27e25935acec77 |
---|---|
oai_identifier_str |
oai:ufs.br:riufs/1415 |
network_acronym_str |
UFS-2 |
network_name_str |
Repositório Institucional da UFS |
repository_id_str |
|
spelling |
Dias, Antônio SantosSilva, Déborah Soares Bispo SantosBarboza, BenhurGarcia, Anuska Conde Fagundes SoaresOliveira, Betejane deEstevam, Charles dos SantosAraújo Neto, VitorSantos, André Luiz Lima Menezes dosScher, RicardoPantaleao, Silmara de Moraes2015-01-29T21:25:36Z2015-01-29T21:25:36Z2013-04SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015.0102-695Xhttps://ri.ufs.br/handle/riufs/1415Creative Commons Attribution LicenseErythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential.Sociedade Brasileira de FarmacognosiaAnsiedadeAgitaçãoInsôniaErythrina velutina WilldInvestigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILInvestigationOfProtective.pdf.jpgInvestigationOfProtective.pdf.jpgGenerated Thumbnailimage/jpeg1663https://ri.ufs.br/jspui/bitstream/riufs/1415/4/InvestigationOfProtective.pdf.jpg6ef0ae95cd083732b0362f7247fa1924MD54ORIGINALInvestigationOfProtective.pdfInvestigationOfProtective.pdfapplication/pdf893047https://ri.ufs.br/jspui/bitstream/riufs/1415/1/InvestigationOfProtective.pdfb7029bccc89009fa82298123910ea539MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1415/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTInvestigationOfProtective.pdf.txtInvestigationOfProtective.pdf.txtExtracted texttext/plain26342https://ri.ufs.br/jspui/bitstream/riufs/1415/3/InvestigationOfProtective.pdf.txt27e4063a8cfb196890a849fb3a171dddMD53riufs/14152016-03-14 11:34:01.093oai:ufs.br:riufs/1415Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2016-03-14T14:34:01Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
title |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
spellingShingle |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa Dias, Antônio Santos Ansiedade Agitação Insônia Erythrina velutina Willd |
title_short |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
title_full |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
title_fullStr |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
title_full_unstemmed |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
title_sort |
Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa |
author |
Dias, Antônio Santos |
author_facet |
Dias, Antônio Santos Silva, Déborah Soares Bispo Santos Barboza, Benhur Garcia, Anuska Conde Fagundes Soares Oliveira, Betejane de Estevam, Charles dos Santos Araújo Neto, Vitor Santos, André Luiz Lima Menezes dos Scher, Ricardo Pantaleao, Silmara de Moraes |
author_role |
author |
author2 |
Silva, Déborah Soares Bispo Santos Barboza, Benhur Garcia, Anuska Conde Fagundes Soares Oliveira, Betejane de Estevam, Charles dos Santos Araújo Neto, Vitor Santos, André Luiz Lima Menezes dos Scher, Ricardo Pantaleao, Silmara de Moraes |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Dias, Antônio Santos Silva, Déborah Soares Bispo Santos Barboza, Benhur Garcia, Anuska Conde Fagundes Soares Oliveira, Betejane de Estevam, Charles dos Santos Araújo Neto, Vitor Santos, André Luiz Lima Menezes dos Scher, Ricardo Pantaleao, Silmara de Moraes |
dc.subject.por.fl_str_mv |
Ansiedade Agitação Insônia Erythrina velutina Willd |
topic |
Ansiedade Agitação Insônia Erythrina velutina Willd |
description |
Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-infl ammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assessed the antigenotoxic effect of E. velutina against the genotoxic effects induced by MMS in the root meristem cells of Allium cepa. Three concentrations of the aqueous extract (100, 200 and 400 mg/L) of this medicinal plant were used in three different types of treatment (pre-, post- and simultaneous). The effects of the extracts on the root meristem cells of A. cepa were analyzed at both macroscopic and microscopic levels. Protective effects were observed at higher concentrations in pre-treatment and in simultaneous treatment. The results suggest that E. velutina may present antigenotoxic properties and demonstrate its chemopreventive potential. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-04 |
dc.date.accessioned.fl_str_mv |
2015-01-29T21:25:36Z |
dc.date.available.fl_str_mv |
2015-01-29T21:25:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/1415 |
dc.identifier.issn.none.fl_str_mv |
0102-695X |
dc.identifier.license.pt_BR.fl_str_mv |
Creative Commons Attribution License |
identifier_str_mv |
SILVA, D. S. B. S. et. al. Investigation of protective effects of erythrina velutina extract against MMS induced damages in the root meristem cells of allium cepa. Revista Brasileira de Farmacognosia, Curitiba, v. 23, n. 2, mar./abr. 2013. Disponível em: <http://www.scielo.br/scielo.php?pid=S0102-695X2013000200011&script=sci_arttext>. Acesso em: 29 jan. 2015. 0102-695X Creative Commons Attribution License |
url |
https://ri.ufs.br/handle/riufs/1415 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFS instname:Universidade Federal de Sergipe (UFS) instacron:UFS |
instname_str |
Universidade Federal de Sergipe (UFS) |
instacron_str |
UFS |
institution |
UFS |
reponame_str |
Repositório Institucional da UFS |
collection |
Repositório Institucional da UFS |
bitstream.url.fl_str_mv |
https://ri.ufs.br/jspui/bitstream/riufs/1415/4/InvestigationOfProtective.pdf.jpg https://ri.ufs.br/jspui/bitstream/riufs/1415/1/InvestigationOfProtective.pdf https://ri.ufs.br/jspui/bitstream/riufs/1415/2/license.txt https://ri.ufs.br/jspui/bitstream/riufs/1415/3/InvestigationOfProtective.pdf.txt |
bitstream.checksum.fl_str_mv |
6ef0ae95cd083732b0362f7247fa1924 b7029bccc89009fa82298123910ea539 8a4605be74aa9ea9d79846c1fba20a33 27e4063a8cfb196890a849fb3a171ddd |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS) |
repository.mail.fl_str_mv |
repositorio@academico.ufs.br |
_version_ |
1793350902378135552 |