Antinociceptive effects of an extract, fraction and an isolated compound of the stem bark of Maytenus rigida
The antinociceptive activity of the Maytenus rigida Mart. (Celastraceae) ethanol extract and its ethyl acetate fraction as well as of (-)-4'-methylepigallocatechin (1), a previously isolated compound, was demonstrated in vivo. ED50 for 1 in the writhing test was 14.14 mg/kg. The acetic acid-ind...
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Sociedade Brasileira de Farmacognosia