Association of MYF5 gene allelic variants with production traits in pigs

• Autor(a) principal: Carmo,Fausto Moreira da Silva
• Data de Publicação: 2005
• Outros Autores: Guimarães,Simone Eliza Facioni, Lopes,Paulo Sávio, Pires,Aldrin Vieira, Guimarães,Marta Fonseca Martins, Silva,Marcos Vinícius Gualberto Barbosa da, Schierholt,Alex Sandro, Silva,Kleibe de Moraes e, Gomide,Lúcio Alberto de Miranda
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Genetics and Molecular Biology
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000300004
• topic: myogenesis; DNA sequencing; pig production; PCR

We studied the phenotypic effects of polymorphisms at the MYF5 gene in a divergent F2 swine population and found that one polymorphism was due to an insertion and another to a deletion. The genotypes of 359 F2 animals were obtained and the Normal/Normal (NN) and Normal/Insertion (NI) genotypes analyzed to determine associations with phenotypic data for performance, carcass and meat quality traits. Significant differences were observed (p < 0.05) between NN and NI animals for drip (NN = 3.14 ± 1.56; NI = 3.69 ± 2.78%), cooking (NN = 32.26 ± 2.41; NI = 33.21 ± 2.31%) and total loss (NN = 34.16 ± 2.63 and NI = 34.97 ± 2.08%). The Deletion marker was not statistically tested. The results indicate that the allelic variant Insertion is associated with a deleterious effect on meat quality traits and should be monitored in marker assisted selection programs.