Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds

Detalhes bibliográficos
Autor(a) principal: Almeida,Sabrina E.M.
Data de Publicação: 2008
Outros Autores: Santos,Luciana B.S., Passos,Daniel T., Corbellini,Ângela O., Lopes,Beatriz M.T., Kirst,Cláudia, Terra,Gustavo, Neves,Jairo P., Gonçalves,Paulo B.D., Moraes,José C.F., Weimer,Tania de Azevedo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400013
Resumo: The genetic diversity of a single nucleotide polymorphism (SNP) at the exon 20 (T945M) of the leptin receptor gene (LEPR) and of three short tandem repeats (STRs BM7225, BMS694, and BMS2145) linked to LEPR was investigated in three beef cattle herds (Brangus Ibagé, Charolais, and Aberdeen Angus). A cheap and effective new method to analyze the T945M polymorphism in cattle populations was developed and the possible role of these polymorphisms in reproduction and weight gain of postpartum cows was evaluated. High levels of genetic diversity were observed with the average heterozygosity of STRs ranging from 0.71 to 0.81. No significant association was detected between LEPR markers and reproductive parameters or daily weight gain. These negative results suggest that the LEPR gene polymorphisms, at least those herein described, do not influence postpartum cows production.
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spelling Genetic polymorphisms at the leptin receptor gene in three beef cattle breedsmolecular markersgenetic diversitycattle productionLEPR gene polymorphismsThe genetic diversity of a single nucleotide polymorphism (SNP) at the exon 20 (T945M) of the leptin receptor gene (LEPR) and of three short tandem repeats (STRs BM7225, BMS694, and BMS2145) linked to LEPR was investigated in three beef cattle herds (Brangus Ibagé, Charolais, and Aberdeen Angus). A cheap and effective new method to analyze the T945M polymorphism in cattle populations was developed and the possible role of these polymorphisms in reproduction and weight gain of postpartum cows was evaluated. High levels of genetic diversity were observed with the average heterozygosity of STRs ranging from 0.71 to 0.81. No significant association was detected between LEPR markers and reproductive parameters or daily weight gain. These negative results suggest that the LEPR gene polymorphisms, at least those herein described, do not influence postpartum cows production.Sociedade Brasileira de Genética2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400013Genetics and Molecular Biology v.31 n.3 2008reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572008000400013info:eu-repo/semantics/openAccessAlmeida,Sabrina E.M.Santos,Luciana B.S.Passos,Daniel T.Corbellini,Ângela O.Lopes,Beatriz M.T.Kirst,CláudiaTerra,GustavoNeves,Jairo P.Gonçalves,Paulo B.D.Moraes,José C.F.Weimer,Tania de Azevedoeng2008-08-18T00:00:00Zoai:scielo:S1415-47572008000400013Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2008-08-18T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
title Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
spellingShingle Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
Almeida,Sabrina E.M.
molecular markers
genetic diversity
cattle production
LEPR gene polymorphisms
title_short Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
title_full Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
title_fullStr Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
title_full_unstemmed Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
title_sort Genetic polymorphisms at the leptin receptor gene in three beef cattle breeds
author Almeida,Sabrina E.M.
author_facet Almeida,Sabrina E.M.
Santos,Luciana B.S.
Passos,Daniel T.
Corbellini,Ângela O.
Lopes,Beatriz M.T.
Kirst,Cláudia
Terra,Gustavo
Neves,Jairo P.
Gonçalves,Paulo B.D.
Moraes,José C.F.
Weimer,Tania de Azevedo
author_role author
author2 Santos,Luciana B.S.
Passos,Daniel T.
Corbellini,Ângela O.
Lopes,Beatriz M.T.
Kirst,Cláudia
Terra,Gustavo
Neves,Jairo P.
Gonçalves,Paulo B.D.
Moraes,José C.F.
Weimer,Tania de Azevedo
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Almeida,Sabrina E.M.
Santos,Luciana B.S.
Passos,Daniel T.
Corbellini,Ângela O.
Lopes,Beatriz M.T.
Kirst,Cláudia
Terra,Gustavo
Neves,Jairo P.
Gonçalves,Paulo B.D.
Moraes,José C.F.
Weimer,Tania de Azevedo
dc.subject.por.fl_str_mv molecular markers
genetic diversity
cattle production
LEPR gene polymorphisms
topic molecular markers
genetic diversity
cattle production
LEPR gene polymorphisms
description The genetic diversity of a single nucleotide polymorphism (SNP) at the exon 20 (T945M) of the leptin receptor gene (LEPR) and of three short tandem repeats (STRs BM7225, BMS694, and BMS2145) linked to LEPR was investigated in three beef cattle herds (Brangus Ibagé, Charolais, and Aberdeen Angus). A cheap and effective new method to analyze the T945M polymorphism in cattle populations was developed and the possible role of these polymorphisms in reproduction and weight gain of postpartum cows was evaluated. High levels of genetic diversity were observed with the average heterozygosity of STRs ranging from 0.71 to 0.81. No significant association was detected between LEPR markers and reproductive parameters or daily weight gain. These negative results suggest that the LEPR gene polymorphisms, at least those herein described, do not influence postpartum cows production.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572008000400013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.31 n.3 2008
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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