Salivary IgA and IgE levels in healthy subjects: relation to age and gender

Detalhes bibliográficos
Autor(a) principal: Jafarzadeh,Abdollah
Data de Publicação: 2010
Outros Autores: Sadeghi,Mostafa, Karam,Gholamreza Asadi, Vazirinejad,Reza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004
Resumo: It has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two milliliters of saliva were collected from all participants, and salivary IgA and IgE levels were measured by the ELISA technique. Mean salivary IgA levels were significantly higher in subjects aged 11-20 years as compared to subjects aged 1-10 years (P < 0.01). Mean salivary IgA levels increased with age up to the age of 60 years, and then slightly decreased in subjects aged 61-70 years. The frequency of subjects with detectable levels of salivary IgE and mean salivary IgE levels gradually increased with age, with maximum levels being observed in the 31-40 years age group and not changing significantly thereafter. The mean levels of salivary IgA and IgE in adults were significantly higher than those observed in children (P < 0.00001 and P < 0.05, respectively). No significant differences were observed between men and women regarding both salivary immunoglobulins. These results showed age-dependent changes of the salivary IgA and IgE levels. Gender had no effect on the salivary levels of IgA and IgE.
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spelling Salivary IgA and IgE levels in healthy subjects: relation to age and genderSalivaImmunoglobulin AImmunoglobulin EAdultChildIt has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two milliliters of saliva were collected from all participants, and salivary IgA and IgE levels were measured by the ELISA technique. Mean salivary IgA levels were significantly higher in subjects aged 11-20 years as compared to subjects aged 1-10 years (P < 0.01). Mean salivary IgA levels increased with age up to the age of 60 years, and then slightly decreased in subjects aged 61-70 years. The frequency of subjects with detectable levels of salivary IgE and mean salivary IgE levels gradually increased with age, with maximum levels being observed in the 31-40 years age group and not changing significantly thereafter. The mean levels of salivary IgA and IgE in adults were significantly higher than those observed in children (P < 0.00001 and P < 0.05, respectively). No significant differences were observed between men and women regarding both salivary immunoglobulins. These results showed age-dependent changes of the salivary IgA and IgE levels. Gender had no effect on the salivary levels of IgA and IgE.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2010-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004Brazilian Oral Research v.24 n.1 2010reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242010000100004info:eu-repo/semantics/openAccessJafarzadeh,AbdollahSadeghi,MostafaKaram,Gholamreza AsadiVazirinejad,Rezaeng2010-03-17T00:00:00Zoai:scielo:S1806-83242010000100004Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2010-03-17T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Salivary IgA and IgE levels in healthy subjects: relation to age and gender
title Salivary IgA and IgE levels in healthy subjects: relation to age and gender
spellingShingle Salivary IgA and IgE levels in healthy subjects: relation to age and gender
Jafarzadeh,Abdollah
Saliva
Immunoglobulin A
Immunoglobulin E
Adult
Child
title_short Salivary IgA and IgE levels in healthy subjects: relation to age and gender
title_full Salivary IgA and IgE levels in healthy subjects: relation to age and gender
title_fullStr Salivary IgA and IgE levels in healthy subjects: relation to age and gender
title_full_unstemmed Salivary IgA and IgE levels in healthy subjects: relation to age and gender
title_sort Salivary IgA and IgE levels in healthy subjects: relation to age and gender
author Jafarzadeh,Abdollah
author_facet Jafarzadeh,Abdollah
Sadeghi,Mostafa
Karam,Gholamreza Asadi
Vazirinejad,Reza
author_role author
author2 Sadeghi,Mostafa
Karam,Gholamreza Asadi
Vazirinejad,Reza
author2_role author
author
author
dc.contributor.author.fl_str_mv Jafarzadeh,Abdollah
Sadeghi,Mostafa
Karam,Gholamreza Asadi
Vazirinejad,Reza
dc.subject.por.fl_str_mv Saliva
Immunoglobulin A
Immunoglobulin E
Adult
Child
topic Saliva
Immunoglobulin A
Immunoglobulin E
Adult
Child
description It has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two milliliters of saliva were collected from all participants, and salivary IgA and IgE levels were measured by the ELISA technique. Mean salivary IgA levels were significantly higher in subjects aged 11-20 years as compared to subjects aged 1-10 years (P < 0.01). Mean salivary IgA levels increased with age up to the age of 60 years, and then slightly decreased in subjects aged 61-70 years. The frequency of subjects with detectable levels of salivary IgE and mean salivary IgE levels gradually increased with age, with maximum levels being observed in the 31-40 years age group and not changing significantly thereafter. The mean levels of salivary IgA and IgE in adults were significantly higher than those observed in children (P < 0.00001 and P < 0.05, respectively). No significant differences were observed between men and women regarding both salivary immunoglobulins. These results showed age-dependent changes of the salivary IgA and IgE levels. Gender had no effect on the salivary levels of IgA and IgE.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242010000100004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.24 n.1 2010
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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