Respiratory muscle strength and lung function in the stages of Parkinson’s disease
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Pneumologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000600203 |
Resumo: | ABSTRACT Objective: To investigate parameters of lung function and respiratory muscle strength in different stages of Parkinson’s disease (PD), as well as to determine their correlation with motor function and quality of life. Methods: This was a cross-sectional study conducted at a referral center for PD in the city of Recife, Brazil. Respiratory muscle strength and lung function, as well as their relationship with motor function and quality of life, were evaluated in patients with PD, stratified by the level of severity, and were compared with the data obtained for a control group. After confirming the normality of data distribution, we performed one-way ANOVA with a post hoc t-test. Results: The sample comprised 66 individuals, in two groups: PD (n = 49) and control (n = 17). All of the parameters investigated showed inverse correlations with PD severity, and there were significant differences among the levels of severity, as well as between the PD and control groups, in terms of the MIP, MEP, FVC, FEV1, and FEF25-75%. The lung function parameters also showed moderate to weak inverse correlations with bradykinesia and rigidity. On a quality of life questionnaire, the total score and mobility domain score both presented a moderate inverse correlation with FVC, FEV1, PEF, and MEP. Conclusions: Respiratory muscle strength and some lung function parameters are impaired from the early stages of PD onward, bradykinesia and rigidity being the cardinal signs that correlate most strongly with impairment of those parameters. Such alterations negatively affect the quality of life of patients with PD. |
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Jornal Brasileiro de Pneumologia (Online) |
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Respiratory muscle strength and lung function in the stages of Parkinson’s diseaseParkinson diseaseRespiratory mechanicsMaximum respiratory pressuresQuality of lifeABSTRACT Objective: To investigate parameters of lung function and respiratory muscle strength in different stages of Parkinson’s disease (PD), as well as to determine their correlation with motor function and quality of life. Methods: This was a cross-sectional study conducted at a referral center for PD in the city of Recife, Brazil. Respiratory muscle strength and lung function, as well as their relationship with motor function and quality of life, were evaluated in patients with PD, stratified by the level of severity, and were compared with the data obtained for a control group. After confirming the normality of data distribution, we performed one-way ANOVA with a post hoc t-test. Results: The sample comprised 66 individuals, in two groups: PD (n = 49) and control (n = 17). All of the parameters investigated showed inverse correlations with PD severity, and there were significant differences among the levels of severity, as well as between the PD and control groups, in terms of the MIP, MEP, FVC, FEV1, and FEF25-75%. The lung function parameters also showed moderate to weak inverse correlations with bradykinesia and rigidity. On a quality of life questionnaire, the total score and mobility domain score both presented a moderate inverse correlation with FVC, FEV1, PEF, and MEP. Conclusions: Respiratory muscle strength and some lung function parameters are impaired from the early stages of PD onward, bradykinesia and rigidity being the cardinal signs that correlate most strongly with impairment of those parameters. Such alterations negatively affect the quality of life of patients with PD.Sociedade Brasileira de Pneumologia e Tisiologia2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000600203Jornal Brasileiro de Pneumologia v.45 n.6 2019reponame:Jornal Brasileiro de Pneumologia (Online)instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)instacron:SBPT10.1590/1806-3713/e20180148info:eu-repo/semantics/openAccessSantos,Rejane Barreto dosFraga,Anderson SantosCoriolano,Maria das Graças Wanderley de SalesTiburtino,Bruna FerreiraLins,Otávio GomesEsteves,Ana Cristina FalcãoAsano,Nadja Maria Jorgeeng2019-09-25T00:00:00Zoai:scielo:S1806-37132019000600203Revistahttp://www.jornaldepneumologia.com.br/default.aspONGhttps://old.scielo.br/oai/scielo-oai.php||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br1806-37561806-3713opendoar:2019-09-25T00:00Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)false |
dc.title.none.fl_str_mv |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
title |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
spellingShingle |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease Santos,Rejane Barreto dos Parkinson disease Respiratory mechanics Maximum respiratory pressures Quality of life |
title_short |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
title_full |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
title_fullStr |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
title_full_unstemmed |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
title_sort |
Respiratory muscle strength and lung function in the stages of Parkinson’s disease |
author |
Santos,Rejane Barreto dos |
author_facet |
Santos,Rejane Barreto dos Fraga,Anderson Santos Coriolano,Maria das Graças Wanderley de Sales Tiburtino,Bruna Ferreira Lins,Otávio Gomes Esteves,Ana Cristina Falcão Asano,Nadja Maria Jorge |
author_role |
author |
author2 |
Fraga,Anderson Santos Coriolano,Maria das Graças Wanderley de Sales Tiburtino,Bruna Ferreira Lins,Otávio Gomes Esteves,Ana Cristina Falcão Asano,Nadja Maria Jorge |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Santos,Rejane Barreto dos Fraga,Anderson Santos Coriolano,Maria das Graças Wanderley de Sales Tiburtino,Bruna Ferreira Lins,Otávio Gomes Esteves,Ana Cristina Falcão Asano,Nadja Maria Jorge |
dc.subject.por.fl_str_mv |
Parkinson disease Respiratory mechanics Maximum respiratory pressures Quality of life |
topic |
Parkinson disease Respiratory mechanics Maximum respiratory pressures Quality of life |
description |
ABSTRACT Objective: To investigate parameters of lung function and respiratory muscle strength in different stages of Parkinson’s disease (PD), as well as to determine their correlation with motor function and quality of life. Methods: This was a cross-sectional study conducted at a referral center for PD in the city of Recife, Brazil. Respiratory muscle strength and lung function, as well as their relationship with motor function and quality of life, were evaluated in patients with PD, stratified by the level of severity, and were compared with the data obtained for a control group. After confirming the normality of data distribution, we performed one-way ANOVA with a post hoc t-test. Results: The sample comprised 66 individuals, in two groups: PD (n = 49) and control (n = 17). All of the parameters investigated showed inverse correlations with PD severity, and there were significant differences among the levels of severity, as well as between the PD and control groups, in terms of the MIP, MEP, FVC, FEV1, and FEF25-75%. The lung function parameters also showed moderate to weak inverse correlations with bradykinesia and rigidity. On a quality of life questionnaire, the total score and mobility domain score both presented a moderate inverse correlation with FVC, FEV1, PEF, and MEP. Conclusions: Respiratory muscle strength and some lung function parameters are impaired from the early stages of PD onward, bradykinesia and rigidity being the cardinal signs that correlate most strongly with impairment of those parameters. Such alterations negatively affect the quality of life of patients with PD. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000600203 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000600203 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-3713/e20180148 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Pneumologia v.45 n.6 2019 reponame:Jornal Brasileiro de Pneumologia (Online) instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) instacron:SBPT |
instname_str |
Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) |
instacron_str |
SBPT |
institution |
SBPT |
reponame_str |
Jornal Brasileiro de Pneumologia (Online) |
collection |
Jornal Brasileiro de Pneumologia (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) |
repository.mail.fl_str_mv |
||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br |
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1750318347690442752 |