The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300016 |
Resumo: | The objective of this study was to evaluate whether demineralized bovine bone (Gen-ox®) alters bone neoformation in rats submitted to alcoholism. Forty male rats were separated into two groups of 20 rats and distributed as follows: Group E1, which received 25% ethanol and a surgical cavity filled only by a blood clot, and Group E2, which received 25% ethanol and a surgical cavity filled with Gen-ox®. The animals were euthanized at 10, 20, 40 and 60 days after surgery and necropsy was performed. The histomorphological and histometric analyses of the area of connective tissue and bone neoformation showed that the reorganization of the bone marrow and full repair of the surgical cavity in Group E1 occurred more quickly than in Group E2. It was also noted that in the final period the animals in Group E2 showed areas of connective tissue and thick bone trabeculae around the particles of the implant. It can be concluded that the use of Gen-ox® delayed the process of bone repair in alcoholic rats, although it can be used as filling material because it shows osteoconductive activity, as evidenced by bone tissue formation around the graft particles. |
id |
UFMG-8_8d5f390a7ed2dbf4ad93d94b11915549 |
---|---|
oai_identifier_str |
oai:scielo:S0102-09352013000300016 |
network_acronym_str |
UFMG-8 |
network_name_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository_id_str |
|
spelling |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholismratbone regenerationalcoholismThe objective of this study was to evaluate whether demineralized bovine bone (Gen-ox®) alters bone neoformation in rats submitted to alcoholism. Forty male rats were separated into two groups of 20 rats and distributed as follows: Group E1, which received 25% ethanol and a surgical cavity filled only by a blood clot, and Group E2, which received 25% ethanol and a surgical cavity filled with Gen-ox®. The animals were euthanized at 10, 20, 40 and 60 days after surgery and necropsy was performed. The histomorphological and histometric analyses of the area of connective tissue and bone neoformation showed that the reorganization of the bone marrow and full repair of the surgical cavity in Group E1 occurred more quickly than in Group E2. It was also noted that in the final period the animals in Group E2 showed areas of connective tissue and thick bone trabeculae around the particles of the implant. It can be concluded that the use of Gen-ox® delayed the process of bone repair in alcoholic rats, although it can be used as filling material because it shows osteoconductive activity, as evidenced by bone tissue formation around the graft particles.Universidade Federal de Minas Gerais, Escola de Veterinária2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300016Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.65 n.3 2013reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352013000300016info:eu-repo/semantics/openAccessBuchaim,R.L.Andreo,J.C.Rodrigues,A. C.Buchaim,D.V.Dias,D.V.Daré,L.R.Roque,D.D.Roque,J.S.eng2013-07-16T00:00:00Zoai:scielo:S0102-09352013000300016Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2013-07-16T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
title |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
spellingShingle |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism Buchaim,R.L. rat bone regeneration alcoholism |
title_short |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
title_full |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
title_fullStr |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
title_full_unstemmed |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
title_sort |
The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism |
author |
Buchaim,R.L. |
author_facet |
Buchaim,R.L. Andreo,J.C. Rodrigues,A. C. Buchaim,D.V. Dias,D.V. Daré,L.R. Roque,D.D. Roque,J.S. |
author_role |
author |
author2 |
Andreo,J.C. Rodrigues,A. C. Buchaim,D.V. Dias,D.V. Daré,L.R. Roque,D.D. Roque,J.S. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Buchaim,R.L. Andreo,J.C. Rodrigues,A. C. Buchaim,D.V. Dias,D.V. Daré,L.R. Roque,D.D. Roque,J.S. |
dc.subject.por.fl_str_mv |
rat bone regeneration alcoholism |
topic |
rat bone regeneration alcoholism |
description |
The objective of this study was to evaluate whether demineralized bovine bone (Gen-ox®) alters bone neoformation in rats submitted to alcoholism. Forty male rats were separated into two groups of 20 rats and distributed as follows: Group E1, which received 25% ethanol and a surgical cavity filled only by a blood clot, and Group E2, which received 25% ethanol and a surgical cavity filled with Gen-ox®. The animals were euthanized at 10, 20, 40 and 60 days after surgery and necropsy was performed. The histomorphological and histometric analyses of the area of connective tissue and bone neoformation showed that the reorganization of the bone marrow and full repair of the surgical cavity in Group E1 occurred more quickly than in Group E2. It was also noted that in the final period the animals in Group E2 showed areas of connective tissue and thick bone trabeculae around the particles of the implant. It can be concluded that the use of Gen-ox® delayed the process of bone repair in alcoholic rats, although it can be used as filling material because it shows osteoconductive activity, as evidenced by bone tissue formation around the graft particles. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300016 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300016 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-09352013000300016 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.65 n.3 2013 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220886401613824 |