Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group

Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical chara...

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Access type:openAccess
Publication Date:2015
Main Author: Felicio, João Soares
Other Authors: Souza, Ana Carolina Contente Braga de, Koury, Camila Cavalcante, Abrahão Neto, João Felício, Miléo, Karem Barbosa, Santos, Flávia Marques, Motta, Ana Regina Bastos, Silva, Denisson Dias, Arbage, Thaís Pontes, Carvalho, Carolina Tavares, Brito, Hana Andrade de Rider, Yamada, Elizabeth Sumi, Cobas, Roberta Arnoldi, Costa, Alessandra Saldanha Matheus Fernandes da, Tannus, Lucianne Righeti Monteiro, Palma, Catia C. Sousa, Japiassú, Letícia Mauricio Garcia, Carneiro, João Regis Ivar, Rodacki, Melanie, Zajdenverg, Lenita, Araujo, Neuza Braga Campos de, Cordeiro, Marilena de Menezes, Luescher, Jorge L., Berardo, Renata Szundy, Nery, Márcia, Cani, Catarina Gomes, Marques, Maria do Carmo Arruda, Calliari, Luís Eduardo Procopio, Noronha, Renata Maria de, Della Manna, Thais, Savoldelli, Roberta Diaz, Penha, Fernanda Garcia, Foss, Milton Cesar, Freitas, Maria Cristina Foss de, Pires, Antonio Carlos, Robles, Fernando Cesar, Negrato, Carlos Antônio, Guedes, Maria de Fátima S., Dib, Sérgio Atala, Dualib, Patricia Medici, Silva, Saulo Cavalcanti da, Sepulveda, Janice, Sampaio, Emerson, Rea, Rosangela Roginski, Faria, Ana Cristina Ravazzani de Almeida, Tschiedel, Balduíno, Lavigne, Suzana Coelho de, Cardozo, Gustavo Adolfo, Azevedo, Mirela Jobim de, Canani, Luis Henrique Santos, Zucatti, Alessandra Teixeira Netto, Coral, Marisa Helena Cesar, Pereira, Daniela Aline, Araújo, Luiz Antonio de, Pedrosa, Hermelinda Cordeiro, Tolentino, Monica, Prado, Flaviene Alves, Rassi, Nelson, Araujo, Leticia B., Fonseca, Reine Marie Chaves, Guedes, Alexis Dourado, Mattos, Odelisa S., Faria, Manuel S., Azulay, Rossana Santiago de Sousa, Forti, Adriana Costa e, Façanha, Cristina Figueiredo Sampaio, Montenegro Júnior, Renan Magalhães, Montenegro, Ana Paula, Melo, Naira Horta, Rezende, Karla Freire, Ramos, Alberto, Jezini, Deborah Laredo, Gomes, Marília de Brito
Document type: Article Other
Language:eng
Portuguese subjects:
English subjects:
Online Access:http://hdl.handle.net/10183/205088
English abstract:Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities.