Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E

Detalhes bibliográficos
Autor(a) principal: Orso, Catiane
Data de Publicação: 2022
Outros Autores: Cony, Bruna Souza de Lima, Silva, J. P., Furtado, Júlio César Veira, Mann, Michele Bertoni, Frazzon, Jeverson, Frazzon, Ana Paula Guedes, Andretta, Ines, Ribeiro, Andrea Machado Leal
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/256411
Resumo: This experiment determined if 2% of gelatin, to improve the levels of proline and glycine in the diet, and 70 mg/kg of vitamin E supplementation would relieve the impaired performance of male Cobb broilers vaccinated for coccidiosis. Half of the chicks were vaccinated via water (live oocysts), while the other half received medication (salinomycin) in the feed until 35 d of age. The effects of coccidiosis vaccine on performance and mRNA levels of genes involved in mucin synthesis, cytokines, trefoil family factor-2 (TFF2), and metabolic processes (CD36) in the jejunum of broilers were measured. Vaccination negatively affected performance in the first 21 d; however, the inclusion of gelatin and vitamin E reduced this negative response. Additionally, supplementation with these nutrients led to an improvement in broilers receiving the coccidiostat (P < 0.05). From 21 to 35 d, birds treated with gelatin and coccidiosis vaccine experienced better body weight gain than birds without gelatin and vitamin E (P < 0.05). Vaccinated chickens had decreased body weight and decreased anti-inflammatory cytokine expression. Fur- thermore, they had increased inflammatory cytokine expression, mucin 2 expression, and TFF2 compared to salinomycin-fed broilers (P < 0.05). Transcripts for IL- 1B, IFN-y, MUC2, TFF2 were decreased while mRNAs for IL-4 and IL-10 increased in salinomycin-fed broilers compared to vaccinated broilers (P < 0.05). In conclusion, broilers vaccinated against coccidiosis increase their pro-inflammatory immune status and mucin expression compared to broilers receiving salinomycin. These events may contribute to lower performance in vaccinated broiler chicks. Moreover, vitamin E and gelatin can minimize the vaccine’s negative immune effects and promote better performance.
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spelling Orso, CatianeCony, Bruna Souza de LimaSilva, J. P.Furtado, Júlio César VeiraMann, Michele BertoniFrazzon, JeversonFrazzon, Ana Paula GuedesAndretta, InesRibeiro, Andrea Machado Leal2023-03-29T03:25:18Z20220032-5791http://hdl.handle.net/10183/256411001164097This experiment determined if 2% of gelatin, to improve the levels of proline and glycine in the diet, and 70 mg/kg of vitamin E supplementation would relieve the impaired performance of male Cobb broilers vaccinated for coccidiosis. Half of the chicks were vaccinated via water (live oocysts), while the other half received medication (salinomycin) in the feed until 35 d of age. The effects of coccidiosis vaccine on performance and mRNA levels of genes involved in mucin synthesis, cytokines, trefoil family factor-2 (TFF2), and metabolic processes (CD36) in the jejunum of broilers were measured. Vaccination negatively affected performance in the first 21 d; however, the inclusion of gelatin and vitamin E reduced this negative response. Additionally, supplementation with these nutrients led to an improvement in broilers receiving the coccidiostat (P < 0.05). From 21 to 35 d, birds treated with gelatin and coccidiosis vaccine experienced better body weight gain than birds without gelatin and vitamin E (P < 0.05). Vaccinated chickens had decreased body weight and decreased anti-inflammatory cytokine expression. Fur- thermore, they had increased inflammatory cytokine expression, mucin 2 expression, and TFF2 compared to salinomycin-fed broilers (P < 0.05). Transcripts for IL- 1B, IFN-y, MUC2, TFF2 were decreased while mRNAs for IL-4 and IL-10 increased in salinomycin-fed broilers compared to vaccinated broilers (P < 0.05). In conclusion, broilers vaccinated against coccidiosis increase their pro-inflammatory immune status and mucin expression compared to broilers receiving salinomycin. These events may contribute to lower performance in vaccinated broiler chicks. Moreover, vitamin E and gelatin can minimize the vaccine’s negative immune effects and promote better performance.application/pdfengPoultry science. Cambridge, UK. Vol. 101, no. 12 (Dec. 2022), 102206, 10 p.CoccidioseFrangoVacinaçãoCoccidiosisNonessentialAmino acidsVaccineVitaminEffect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin EEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001164097.pdf.txt001164097.pdf.txtExtracted Texttext/plain43045http://www.lume.ufrgs.br/bitstream/10183/256411/2/001164097.pdf.txt5f4c55e2dcbd1277ab34c5a775ef5955MD52ORIGINAL001164097.pdfTexto completo (inglês)application/pdf1486298http://www.lume.ufrgs.br/bitstream/10183/256411/1/001164097.pdf578d0ab103c7d022c13965a3fda15f98MD5110183/2564112023-03-30 03:23:50.783103oai:www.lume.ufrgs.br:10183/256411Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-03-30T06:23:50Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
title Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
spellingShingle Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
Orso, Catiane
Coccidiose
Frango
Vacinação
Coccidiosis
Nonessential
Amino acids
Vaccine
Vitamin
title_short Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
title_full Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
title_fullStr Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
title_full_unstemmed Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
title_sort Effect of live Eimeria vaccination or salinomycin on growth and immune status in broiler chickens receiving in-feed inclusion of gelatin and vitamin E
author Orso, Catiane
author_facet Orso, Catiane
Cony, Bruna Souza de Lima
Silva, J. P.
Furtado, Júlio César Veira
Mann, Michele Bertoni
Frazzon, Jeverson
Frazzon, Ana Paula Guedes
Andretta, Ines
Ribeiro, Andrea Machado Leal
author_role author
author2 Cony, Bruna Souza de Lima
Silva, J. P.
Furtado, Júlio César Veira
Mann, Michele Bertoni
Frazzon, Jeverson
Frazzon, Ana Paula Guedes
Andretta, Ines
Ribeiro, Andrea Machado Leal
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Orso, Catiane
Cony, Bruna Souza de Lima
Silva, J. P.
Furtado, Júlio César Veira
Mann, Michele Bertoni
Frazzon, Jeverson
Frazzon, Ana Paula Guedes
Andretta, Ines
Ribeiro, Andrea Machado Leal
dc.subject.por.fl_str_mv Coccidiose
Frango
Vacinação
topic Coccidiose
Frango
Vacinação
Coccidiosis
Nonessential
Amino acids
Vaccine
Vitamin
dc.subject.eng.fl_str_mv Coccidiosis
Nonessential
Amino acids
Vaccine
Vitamin
description This experiment determined if 2% of gelatin, to improve the levels of proline and glycine in the diet, and 70 mg/kg of vitamin E supplementation would relieve the impaired performance of male Cobb broilers vaccinated for coccidiosis. Half of the chicks were vaccinated via water (live oocysts), while the other half received medication (salinomycin) in the feed until 35 d of age. The effects of coccidiosis vaccine on performance and mRNA levels of genes involved in mucin synthesis, cytokines, trefoil family factor-2 (TFF2), and metabolic processes (CD36) in the jejunum of broilers were measured. Vaccination negatively affected performance in the first 21 d; however, the inclusion of gelatin and vitamin E reduced this negative response. Additionally, supplementation with these nutrients led to an improvement in broilers receiving the coccidiostat (P < 0.05). From 21 to 35 d, birds treated with gelatin and coccidiosis vaccine experienced better body weight gain than birds without gelatin and vitamin E (P < 0.05). Vaccinated chickens had decreased body weight and decreased anti-inflammatory cytokine expression. Fur- thermore, they had increased inflammatory cytokine expression, mucin 2 expression, and TFF2 compared to salinomycin-fed broilers (P < 0.05). Transcripts for IL- 1B, IFN-y, MUC2, TFF2 were decreased while mRNAs for IL-4 and IL-10 increased in salinomycin-fed broilers compared to vaccinated broilers (P < 0.05). In conclusion, broilers vaccinated against coccidiosis increase their pro-inflammatory immune status and mucin expression compared to broilers receiving salinomycin. These events may contribute to lower performance in vaccinated broiler chicks. Moreover, vitamin E and gelatin can minimize the vaccine’s negative immune effects and promote better performance.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-03-29T03:25:18Z
dc.type.driver.fl_str_mv Estrangeiro
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/256411
dc.identifier.issn.pt_BR.fl_str_mv 0032-5791
dc.identifier.nrb.pt_BR.fl_str_mv 001164097
identifier_str_mv 0032-5791
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url http://hdl.handle.net/10183/256411
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Poultry science. Cambridge, UK. Vol. 101, no. 12 (Dec. 2022), 102206, 10 p.
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