Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment

Detalhes bibliográficos
Autor(a) principal: Laskoski,Luciane Maria
Data de Publicação: 2013
Outros Autores: Valadão,Carlos Augusto Araújo, Vasconcelos,Rosemeri de Oliveira, Ferrucci,Danilo, Silva,Juliete Aparecida Francisco, Machado,Dagmar Ruth Stach, Doria,Renata Gebara Sampaio, Mendonça,Fabio de Sousa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Ciência Rural
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000100012
Resumo: Twenty horses were used in the experiment, for composed control group, (Cg) instrumented group, (Ig;without intestinal obstruction), treated group (Tg;submitted to intestinal obstruction and hydrocortisone treatment) and non-treated group (Ntg;submitted to intestinal obstruction without treatment). Immunohistochemistry and zymography techniques were used for researches on MMPs 2 and 9 in horse hoof laminae. There was an increase in the expression of MMP-2 in animals of Tg and Ntg. MMP-9 increased on animals from groups Ntg and Ig, however there was no rise of this MMP on the Tg when compared to the other groups in the immunohistochemistry analysis. Based on the results, it was observed that the intestinal injury caused by enterotomy and intestinal obstruction raise the quantities of MMPs in the hoof laminae.
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spelling Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatmentlaminitismetalloproteasehorsezymographyimmunohistochemistryTwenty horses were used in the experiment, for composed control group, (Cg) instrumented group, (Ig;without intestinal obstruction), treated group (Tg;submitted to intestinal obstruction and hydrocortisone treatment) and non-treated group (Ntg;submitted to intestinal obstruction without treatment). Immunohistochemistry and zymography techniques were used for researches on MMPs 2 and 9 in horse hoof laminae. There was an increase in the expression of MMP-2 in animals of Tg and Ntg. MMP-9 increased on animals from groups Ntg and Ig, however there was no rise of this MMP on the Tg when compared to the other groups in the immunohistochemistry analysis. Based on the results, it was observed that the intestinal injury caused by enterotomy and intestinal obstruction raise the quantities of MMPs in the hoof laminae.Universidade Federal de Santa Maria2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000100012Ciência Rural v.43 n.1 2013reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/S0103-84782013000100012info:eu-repo/semantics/openAccessLaskoski,Luciane MariaValadão,Carlos Augusto AraújoVasconcelos,Rosemeri de OliveiraFerrucci,DaniloSilva,Juliete Aparecida FranciscoMachado,Dagmar Ruth StachDoria,Renata Gebara SampaioMendonça,Fabio de Sousaeng2016-08-16T00:00:00ZRevista
dc.title.none.fl_str_mv Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
title Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
spellingShingle Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
Laskoski,Luciane Maria
laminitis
metalloprotease
horse
zymography
immunohistochemistry
title_short Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
title_full Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
title_fullStr Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
title_full_unstemmed Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
title_sort Expression of matrix metalloproteases-2 and -9 in horse hoof laminae after intestinal obstruction, with or without Hydrocortisone treatment
author Laskoski,Luciane Maria
author_facet Laskoski,Luciane Maria
Valadão,Carlos Augusto Araújo
Vasconcelos,Rosemeri de Oliveira
Ferrucci,Danilo
Silva,Juliete Aparecida Francisco
Machado,Dagmar Ruth Stach
Doria,Renata Gebara Sampaio
Mendonça,Fabio de Sousa
author_role author
author2 Valadão,Carlos Augusto Araújo
Vasconcelos,Rosemeri de Oliveira
Ferrucci,Danilo
Silva,Juliete Aparecida Francisco
Machado,Dagmar Ruth Stach
Doria,Renata Gebara Sampaio
Mendonça,Fabio de Sousa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Laskoski,Luciane Maria
Valadão,Carlos Augusto Araújo
Vasconcelos,Rosemeri de Oliveira
Ferrucci,Danilo
Silva,Juliete Aparecida Francisco
Machado,Dagmar Ruth Stach
Doria,Renata Gebara Sampaio
Mendonça,Fabio de Sousa
dc.subject.por.fl_str_mv laminitis
metalloprotease
horse
zymography
immunohistochemistry
topic laminitis
metalloprotease
horse
zymography
immunohistochemistry
description Twenty horses were used in the experiment, for composed control group, (Cg) instrumented group, (Ig;without intestinal obstruction), treated group (Tg;submitted to intestinal obstruction and hydrocortisone treatment) and non-treated group (Ntg;submitted to intestinal obstruction without treatment). Immunohistochemistry and zymography techniques were used for researches on MMPs 2 and 9 in horse hoof laminae. There was an increase in the expression of MMP-2 in animals of Tg and Ntg. MMP-9 increased on animals from groups Ntg and Ig, however there was no rise of this MMP on the Tg when compared to the other groups in the immunohistochemistry analysis. Based on the results, it was observed that the intestinal injury caused by enterotomy and intestinal obstruction raise the quantities of MMPs in the hoof laminae.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000100012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000100012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-84782013000100012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Ciência Rural v.43 n.1 2013
reponame:Ciência Rural
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Ciência Rural
collection Ciência Rural
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1749140542340464640

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