Human papillomavirus infection in Brazilian women with normal cervical cytology.
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFOP |
Texto Completo: | http://www.repositorio.ufop.br/handle/123456789/4030 http://dx.doi.org/10.1590/S1517-83822008000300031 |
Resumo: | We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples of 399 women, received for routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive specimens were typed by RFLP. A structured epidemiological questionnaire was administered to each woman. HPV prevalence among these cytologically normal women was 11%. Twelve viral types were detected, the most common being HPV-16, -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral types were detected in 61% of the infected women and 27% of the infected women had multiple HPV infections. Significant associations of HPV infection were found with age, literacy, residence, marital status, lifetime number of sexual partners, and parity. We detected a great diversity of HPV types in women with normal cytology. This kind of information about local populations is useful for HPV prevention and vaccination strategies. |
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Miranda, Priscila Mayrink dePitol, Bruna Caroline VieiraMoran, M. S.Silva, N. N. T.Felix, P. M.Lima Filho, José Luiz deCarneiro, Cláudia MartinsSilva, Ismael Dale Cotrim Guerreiro daCarvalho, Rodrigo Franco deLima, Angélica AlvesBeçak, WillyStocco, Rita de Cássia2014-11-24T15:52:14Z2014-11-24T15:52:14Z2012MIRANDA, P. M. de et al. Human papillomavirus infection in Brazilian women with normal cervical cytology. Genetics and Molecular Research, v. 11, p. 1752-1761, 2012. Disponível em: <http://www.scielo.br/scielo.php?pid=S1517-83822008000300031&script=sci_abstract&tlng=es>. Acesso em: 20 ago. 2014.1676-5680http://www.repositorio.ufop.br/handle/123456789/4030http://dx.doi.org/10.1590/S1517-83822008000300031We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples of 399 women, received for routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive specimens were typed by RFLP. A structured epidemiological questionnaire was administered to each woman. HPV prevalence among these cytologically normal women was 11%. Twelve viral types were detected, the most common being HPV-16, -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral types were detected in 61% of the infected women and 27% of the infected women had multiple HPV infections. Significant associations of HPV infection were found with age, literacy, residence, marital status, lifetime number of sexual partners, and parity. We detected a great diversity of HPV types in women with normal cytology. This kind of information about local populations is useful for HPV prevention and vaccination strategies.Human papillomavirusCervical cancer screeningNormal cytologyEpidemiologyRisk factorsHuman papillomavirus infection in Brazilian women with normal cervical cytology.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleA Revista Genetics and Molecular Biology permite que o Repositório Institucional da Universidade Federal de Ouro Preto (UFOP) deposite uma cópia eletrônica dos artigos publicados por esse periódico em que ao menos um dos autores faça parte da comunidade cientifica da UFOP. Fonte: Licença concedida por email enviado no dia 19 nov. 2013.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFOPinstname:Universidade Federal de Ouro Preto (UFOP)instacron:UFOPLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://www.repositorio.ufop.br/bitstream/123456789/4030/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALARTIGO_HumanpappilomavirusInfection.pdfARTIGO_HumanpappilomavirusInfection.pdfapplication/pdf523530http://www.repositorio.ufop.br/bitstream/123456789/4030/1/ARTIGO_HumanpappilomavirusInfection.pdffc5d749c626730e62cdbc3b376b4153dMD51123456789/40302019-05-13 18:08:49.315oai:localhost: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Repositório InstitucionalPUBhttp://www.repositorio.ufop.br/oai/requestrepositorio@ufop.edu.bropendoar:32332019-05-13T22:08:49Repositório Institucional da UFOP - Universidade Federal de Ouro Preto (UFOP)false |
dc.title.pt_BR.fl_str_mv |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
title |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
spellingShingle |
Human papillomavirus infection in Brazilian women with normal cervical cytology. Miranda, Priscila Mayrink de Human papillomavirus Cervical cancer screening Normal cytology Epidemiology Risk factors |
title_short |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
title_full |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
title_fullStr |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
title_full_unstemmed |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
title_sort |
Human papillomavirus infection in Brazilian women with normal cervical cytology. |
author |
Miranda, Priscila Mayrink de |
author_facet |
Miranda, Priscila Mayrink de Pitol, Bruna Caroline Vieira Moran, M. S. Silva, N. N. T. Felix, P. M. Lima Filho, José Luiz de Carneiro, Cláudia Martins Silva, Ismael Dale Cotrim Guerreiro da Carvalho, Rodrigo Franco de Lima, Angélica Alves Beçak, Willy Stocco, Rita de Cássia |
author_role |
author |
author2 |
Pitol, Bruna Caroline Vieira Moran, M. S. Silva, N. N. T. Felix, P. M. Lima Filho, José Luiz de Carneiro, Cláudia Martins Silva, Ismael Dale Cotrim Guerreiro da Carvalho, Rodrigo Franco de Lima, Angélica Alves Beçak, Willy Stocco, Rita de Cássia |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Miranda, Priscila Mayrink de Pitol, Bruna Caroline Vieira Moran, M. S. Silva, N. N. T. Felix, P. M. Lima Filho, José Luiz de Carneiro, Cláudia Martins Silva, Ismael Dale Cotrim Guerreiro da Carvalho, Rodrigo Franco de Lima, Angélica Alves Beçak, Willy Stocco, Rita de Cássia |
dc.subject.por.fl_str_mv |
Human papillomavirus Cervical cancer screening Normal cytology Epidemiology Risk factors |
topic |
Human papillomavirus Cervical cancer screening Normal cytology Epidemiology Risk factors |
description |
We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples of 399 women, received for routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive specimens were typed by RFLP. A structured epidemiological questionnaire was administered to each woman. HPV prevalence among these cytologically normal women was 11%. Twelve viral types were detected, the most common being HPV-16, -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral types were detected in 61% of the infected women and 27% of the infected women had multiple HPV infections. Significant associations of HPV infection were found with age, literacy, residence, marital status, lifetime number of sexual partners, and parity. We detected a great diversity of HPV types in women with normal cytology. This kind of information about local populations is useful for HPV prevention and vaccination strategies. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2014-11-24T15:52:14Z |
dc.date.available.fl_str_mv |
2014-11-24T15:52:14Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MIRANDA, P. M. de et al. Human papillomavirus infection in Brazilian women with normal cervical cytology. Genetics and Molecular Research, v. 11, p. 1752-1761, 2012. Disponível em: <http://www.scielo.br/scielo.php?pid=S1517-83822008000300031&script=sci_abstract&tlng=es>. Acesso em: 20 ago. 2014. |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufop.br/handle/123456789/4030 |
dc.identifier.issn.none.fl_str_mv |
1676-5680 |
dc.identifier.doi.none.fl_str_mv |
http://dx.doi.org/10.1590/S1517-83822008000300031 |
identifier_str_mv |
MIRANDA, P. M. de et al. Human papillomavirus infection in Brazilian women with normal cervical cytology. Genetics and Molecular Research, v. 11, p. 1752-1761, 2012. Disponível em: <http://www.scielo.br/scielo.php?pid=S1517-83822008000300031&script=sci_abstract&tlng=es>. Acesso em: 20 ago. 2014. 1676-5680 |
url |
http://www.repositorio.ufop.br/handle/123456789/4030 http://dx.doi.org/10.1590/S1517-83822008000300031 |
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eng |
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