Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA)
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/6244 http://dx.doi.org/10.1590/S1807-59322011000600004 |
Resumo: | OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634). RESULTS: Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment. CONCLUSION: The main clinical manifestations of severe allergic reactions were cutaneous. The etiologic agents that were identified as causing these acute episodes differed according to age group. Following in order: drugs (31.2%), foods (23.3% and insect stings (14.9%) in adults with foods predominance in children. Treatment provided for acute anaphylactic reactions was not appropriate. It is necessary to improve educational programs in order to enhance the knowledge on this potentially fatal emergency. |
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Solé, Dirceu [UNIFESP]Ivancevich, Juan CarlosBorges, Mario SanchezCoelho, Magna AdaciRosario Filho, Nelson AugustoArdusso, Ledit Ramón FranciscoBernd, Luis Antônio GuerraUniversidade Federal de São Paulo (UNIFESP)Universidad del Salvador Medical School ImmunologyClínica Santa Isabel Head of the Division of Allergy and ImmunologyCentro Médico-Docente La Trinidad Allergy and Clinical Immunology DepartmentClínica El Avila Head of Allergy and Immunology DepartmentUniversity of Montes ClarosFederal University of Paraná Department of PediatricsNational University of Rosario Faculty of Medical SciencesFederal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and Immunopathology2015-06-14T13:42:51Z2015-06-14T13:42:51Z2011-01-01Clinics. Faculdade de Medicina / USP, v. 66, n. 6, p. 943-947, 2011.1807-5932http://repositorio.unifesp.br/handle/11600/6244http://dx.doi.org/10.1590/S1807-59322011000600004S1807-59322011000600004.pdfS1807-5932201100060000410.1590/S1807-59322011000600004WOS:000293410000004OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634). RESULTS: Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment. CONCLUSION: The main clinical manifestations of severe allergic reactions were cutaneous. The etiologic agents that were identified as causing these acute episodes differed according to age group. Following in order: drugs (31.2%), foods (23.3% and insect stings (14.9%) in adults with foods predominance in children. Treatment provided for acute anaphylactic reactions was not appropriate. It is necessary to improve educational programs in order to enhance the knowledge on this potentially fatal emergency.Federal University of São Paulo Clinical Immunology and Rheumatology Department of Pediatrics Division of AllergyUniversidad del Salvador Medical School ImmunologyClínica Santa Isabel Head of the Division of Allergy and ImmunologyCentro Médico-Docente La Trinidad Allergy and Clinical Immunology DepartmentClínica El Avila Head of Allergy and Immunology DepartmentUniversity of Montes ClarosFederal University of Paraná Department of PediatricsNational University of Rosario Faculty of Medical SciencesFederal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and ImmunopathologyUNIFESP, Clinical Immunology and Rheumatology Department of Pediatrics Division of AllergySciELO943-947engFaculdade de Medicina / USPClinicsAnaphylaxisDrugsFoodHymenoptera spEpinephrineAnaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1807-59322011000600004.pdfapplication/pdf130635${dspace.ui.url}/bitstream/11600/6244/1/S1807-59322011000600004.pdff2738577d536f1aabb68dbfc88076cbbMD51open accessTEXTS1807-59322011000600004.pdf.txtS1807-59322011000600004.pdf.txtExtracted texttext/plain29566${dspace.ui.url}/bitstream/11600/6244/21/S1807-59322011000600004.pdf.txt3e7fda429573cb2db020c3a2c0645239MD521open accessTHUMBNAILS1807-59322011000600004.pdf.jpgS1807-59322011000600004.pdf.jpgIM Thumbnailimage/jpeg7059${dspace.ui.url}/bitstream/11600/6244/23/S1807-59322011000600004.pdf.jpg94bee526b6f71eebbad5b0a76bbf318eMD523open access11600/62442023-06-05 19:59:19.027open accessoai:repositorio.unifesp.br:11600/6244Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:59:19Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
title |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
spellingShingle |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) Solé, Dirceu [UNIFESP] Anaphylaxis Drugs Food Hymenoptera sp Epinephrine |
title_short |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
title_full |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
title_fullStr |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
title_full_unstemmed |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
title_sort |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA) |
author |
Solé, Dirceu [UNIFESP] |
author_facet |
Solé, Dirceu [UNIFESP] Ivancevich, Juan Carlos Borges, Mario Sanchez Coelho, Magna Adaci Rosario Filho, Nelson Augusto Ardusso, Ledit Ramón Francisco Bernd, Luis Antônio Guerra |
author_role |
author |
author2 |
Ivancevich, Juan Carlos Borges, Mario Sanchez Coelho, Magna Adaci Rosario Filho, Nelson Augusto Ardusso, Ledit Ramón Francisco Bernd, Luis Antônio Guerra |
author2_role |
author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidad del Salvador Medical School Immunology Clínica Santa Isabel Head of the Division of Allergy and Immunology Centro Médico-Docente La Trinidad Allergy and Clinical Immunology Department Clínica El Avila Head of Allergy and Immunology Department University of Montes Claros Federal University of Paraná Department of Pediatrics National University of Rosario Faculty of Medical Sciences Federal Faculty Foundation of Medical Sciences of Porto Alegre Division of Immunology and Immunopathology |
dc.contributor.author.fl_str_mv |
Solé, Dirceu [UNIFESP] Ivancevich, Juan Carlos Borges, Mario Sanchez Coelho, Magna Adaci Rosario Filho, Nelson Augusto Ardusso, Ledit Ramón Francisco Bernd, Luis Antônio Guerra |
dc.subject.eng.fl_str_mv |
Anaphylaxis Drugs Food Hymenoptera sp Epinephrine |
topic |
Anaphylaxis Drugs Food Hymenoptera sp Epinephrine |
description |
OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634). RESULTS: Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment. CONCLUSION: The main clinical manifestations of severe allergic reactions were cutaneous. The etiologic agents that were identified as causing these acute episodes differed according to age group. Following in order: drugs (31.2%), foods (23.3% and insect stings (14.9%) in adults with foods predominance in children. Treatment provided for acute anaphylactic reactions was not appropriate. It is necessary to improve educational programs in order to enhance the knowledge on this potentially fatal emergency. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-01-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:42:51Z |
dc.date.available.fl_str_mv |
2015-06-14T13:42:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Clinics. Faculdade de Medicina / USP, v. 66, n. 6, p. 943-947, 2011. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/6244 http://dx.doi.org/10.1590/S1807-59322011000600004 |
dc.identifier.issn.none.fl_str_mv |
1807-5932 |
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S1807-59322011000600004.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1807-59322011000600004 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S1807-59322011000600004 |
dc.identifier.wos.none.fl_str_mv |
WOS:000293410000004 |
identifier_str_mv |
Clinics. Faculdade de Medicina / USP, v. 66, n. 6, p. 943-947, 2011. 1807-5932 S1807-59322011000600004.pdf S1807-59322011000600004 10.1590/S1807-59322011000600004 WOS:000293410000004 |
url |
http://repositorio.unifesp.br/handle/11600/6244 http://dx.doi.org/10.1590/S1807-59322011000600004 |
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eng |
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eng |
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Clinics |
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openAccess |
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943-947 |
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Faculdade de Medicina / USP |
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Faculdade de Medicina / USP |
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