Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/29519 http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x |
Resumo: | Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED. |
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Andrade, Enrico deMesquita, Alexandre A. deClaro, Joaquim de Almeida [UNIFESP]Andrade, Priscila M. deOrtiz, Valdemar [UNIFESP]Paranhos, MarioSrougi, MiguelUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)2016-01-24T12:41:53Z2016-01-24T12:41:53Z2007-03-01Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007.1008-682Xhttp://repositorio.unifesp.br/handle/11600/29519http://dx.doi.org/10.1111/j.1745-7262.2007.00210.xWOS000244880800010.pdf10.1111/j.1745-7262.2007.00210.xWOS:000244880800010Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED.Univ São Paulo, Div Urol Clin, Sector Sexual Med, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilWeb of Science241-244engBlackwell PublishingAsian Journal of Andrologypenisimpotenceginsengpenile erectionStudy of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunctioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000244880800010.pdfapplication/pdf210975${dspace.ui.url}/bitstream/11600/29519/1/WOS000244880800010.pdf4c83e039ebea94cc9e90c08cb79ab483MD51open accessTEXTWOS000244880800010.pdf.txtWOS000244880800010.pdf.txtExtracted texttext/plain16629${dspace.ui.url}/bitstream/11600/29519/2/WOS000244880800010.pdf.txtb443b876ff2c6c43bfa9473bf3d24e84MD52open access11600/295192022-11-03 10:40:51.632open accessoai:repositorio.unifesp.br:11600/29519Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:27:51.916314Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
spellingShingle |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction Andrade, Enrico de penis impotence ginseng penile erection |
title_short |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_full |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_fullStr |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_full_unstemmed |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_sort |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
author |
Andrade, Enrico de |
author_facet |
Andrade, Enrico de Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
author_role |
author |
author2 |
Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
author2_role |
author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Andrade, Enrico de Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
dc.subject.eng.fl_str_mv |
penis impotence ginseng penile erection |
topic |
penis impotence ginseng penile erection |
description |
Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-03-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:41:53Z |
dc.date.available.fl_str_mv |
2016-01-24T12:41:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/29519 http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x |
dc.identifier.issn.none.fl_str_mv |
1008-682X |
dc.identifier.file.none.fl_str_mv |
WOS000244880800010.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1111/j.1745-7262.2007.00210.x |
dc.identifier.wos.none.fl_str_mv |
WOS:000244880800010 |
identifier_str_mv |
Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007. 1008-682X WOS000244880800010.pdf 10.1111/j.1745-7262.2007.00210.x WOS:000244880800010 |
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http://repositorio.unifesp.br/handle/11600/29519 http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x |
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eng |
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Asian Journal of Andrology |
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openAccess |
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241-244 |
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Blackwell Publishing |
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Blackwell Publishing |
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