Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia
Autor(a) principal: | |
---|---|
Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/1719 http://dx.doi.org/10.1590/S0100-879X2003000600002 |
Resumo: | The objective of the present study was to determine the effect of cellulose on intestinal iron absorption in rats during recovery from iron deficiency anemia. Twenty-one-day-old male Wistar-EPM rats were fed an iron-free ration for two weeks to induce anemia. At 5 weeks of age, the rats were divided into two groups (both groups receiving 35 mg of elemental iron per kg diet): cellulose group (N = 12), receiving a diet containing 100 g of cellulose/kg and control (N = 12), receiving a diet containing no cellulose. The fresh weight of the feces collected over a 3-day period between the 15th and 18th day of dietary treatment was 10.7 ± 3.5 g in the group receiving cellulose and 1.9 ± 1.2 g in the control group (P<0.001). Total food intake was higher in the cellulose group (343.4 ± 22.0 g) than in the control (322.1 ± 13.1 g, P = 0.009) during the 3 weeks of dietary treatment. No significant difference was observed in weight gain (cellulose group = 132.8 ± 19.2, control = 128.0 ± 16.3 g), hemoglobin increment (cellulose group = 8.0 ± 0.8, control = 8.0 ± 1.0 g/dl), hemoglobin level (cellulose group = 12.3 ± 1.2, control = 12.1 ± 1.3 g/dl) or in hepatic iron levels (cellulose group = 333.6 ± 112.4, control = 398.4 ± 168.0 µg/g dry tissue). We conclude that cellulose does not adversely affect the regeneration of hemoglobin, hepatic iron level or the growth of rats during recovery from iron deficiency anemia. |
id |
UFSP_6fd19a343d033bb3f956a336e02eb44c |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br:11600/1719 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Catani, M. [UNIFESP]Amancio, Olga Maria Silverio [UNIFESP]Fagundes-Neto, Ulisses [UNIFESP]Morais, Mauro Batista de [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2015-06-14T13:30:00Z2015-06-14T13:30:00Z2003-06-01Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 36, n. 6, p. 693-697, 2003.0100-879Xhttp://repositorio.unifesp.br/handle/11600/1719http://dx.doi.org/10.1590/S0100-879X2003000600002S0100-879X2003000600002.pdfS0100-879X200300060000210.1590/S0100-879X2003000600002WOS:000183866400002The objective of the present study was to determine the effect of cellulose on intestinal iron absorption in rats during recovery from iron deficiency anemia. Twenty-one-day-old male Wistar-EPM rats were fed an iron-free ration for two weeks to induce anemia. At 5 weeks of age, the rats were divided into two groups (both groups receiving 35 mg of elemental iron per kg diet): cellulose group (N = 12), receiving a diet containing 100 g of cellulose/kg and control (N = 12), receiving a diet containing no cellulose. The fresh weight of the feces collected over a 3-day period between the 15th and 18th day of dietary treatment was 10.7 ± 3.5 g in the group receiving cellulose and 1.9 ± 1.2 g in the control group (P<0.001). Total food intake was higher in the cellulose group (343.4 ± 22.0 g) than in the control (322.1 ± 13.1 g, P = 0.009) during the 3 weeks of dietary treatment. No significant difference was observed in weight gain (cellulose group = 132.8 ± 19.2, control = 128.0 ± 16.3 g), hemoglobin increment (cellulose group = 8.0 ± 0.8, control = 8.0 ± 1.0 g/dl), hemoglobin level (cellulose group = 12.3 ± 1.2, control = 12.1 ± 1.3 g/dl) or in hepatic iron levels (cellulose group = 333.6 ± 112.4, control = 398.4 ± 168.0 µg/g dry tissue). We conclude that cellulose does not adversely affect the regeneration of hemoglobin, hepatic iron level or the growth of rats during recovery from iron deficiency anemia.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de PediatriaUNIFESP, EPM, Depto. de PediatriaSciELO693-697engAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological ResearchIron deficiencyDietary fiberCelluloseIron absorptionDietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS0100-879X2003000600002.pdfapplication/pdf482584${dspace.ui.url}/bitstream/11600/1719/1/S0100-879X2003000600002.pdf47eb81b648c51858c7f3fc79549ce79dMD51open accessTEXTS0100-879X2003000600002.pdf.txtS0100-879X2003000600002.pdf.txtExtracted texttext/plain18203${dspace.ui.url}/bitstream/11600/1719/21/S0100-879X2003000600002.pdf.txt1a11278db5192bd33ae40a1b4b492a53MD521open accessTHUMBNAILS0100-879X2003000600002.pdf.jpgS0100-879X2003000600002.pdf.jpgIM Thumbnailimage/jpeg5631${dspace.ui.url}/bitstream/11600/1719/23/S0100-879X2003000600002.pdf.jpg6375795a8f7658813b93bd7b61c762d6MD523open access11600/17192023-06-05 19:23:19.67open accessoai:repositorio.unifesp.br:11600/1719Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:23:19Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
title |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
spellingShingle |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia Catani, M. [UNIFESP] Iron deficiency Dietary fiber Cellulose Iron absorption |
title_short |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
title_full |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
title_fullStr |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
title_full_unstemmed |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
title_sort |
Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia |
author |
Catani, M. [UNIFESP] |
author_facet |
Catani, M. [UNIFESP] Amancio, Olga Maria Silverio [UNIFESP] Fagundes-Neto, Ulisses [UNIFESP] Morais, Mauro Batista de [UNIFESP] |
author_role |
author |
author2 |
Amancio, Olga Maria Silverio [UNIFESP] Fagundes-Neto, Ulisses [UNIFESP] Morais, Mauro Batista de [UNIFESP] |
author2_role |
author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Catani, M. [UNIFESP] Amancio, Olga Maria Silverio [UNIFESP] Fagundes-Neto, Ulisses [UNIFESP] Morais, Mauro Batista de [UNIFESP] |
dc.subject.eng.fl_str_mv |
Iron deficiency Dietary fiber Cellulose Iron absorption |
topic |
Iron deficiency Dietary fiber Cellulose Iron absorption |
description |
The objective of the present study was to determine the effect of cellulose on intestinal iron absorption in rats during recovery from iron deficiency anemia. Twenty-one-day-old male Wistar-EPM rats were fed an iron-free ration for two weeks to induce anemia. At 5 weeks of age, the rats were divided into two groups (both groups receiving 35 mg of elemental iron per kg diet): cellulose group (N = 12), receiving a diet containing 100 g of cellulose/kg and control (N = 12), receiving a diet containing no cellulose. The fresh weight of the feces collected over a 3-day period between the 15th and 18th day of dietary treatment was 10.7 ± 3.5 g in the group receiving cellulose and 1.9 ± 1.2 g in the control group (P<0.001). Total food intake was higher in the cellulose group (343.4 ± 22.0 g) than in the control (322.1 ± 13.1 g, P = 0.009) during the 3 weeks of dietary treatment. No significant difference was observed in weight gain (cellulose group = 132.8 ± 19.2, control = 128.0 ± 16.3 g), hemoglobin increment (cellulose group = 8.0 ± 0.8, control = 8.0 ± 1.0 g/dl), hemoglobin level (cellulose group = 12.3 ± 1.2, control = 12.1 ± 1.3 g/dl) or in hepatic iron levels (cellulose group = 333.6 ± 112.4, control = 398.4 ± 168.0 µg/g dry tissue). We conclude that cellulose does not adversely affect the regeneration of hemoglobin, hepatic iron level or the growth of rats during recovery from iron deficiency anemia. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003-06-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:30:00Z |
dc.date.available.fl_str_mv |
2015-06-14T13:30:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 36, n. 6, p. 693-697, 2003. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/1719 http://dx.doi.org/10.1590/S0100-879X2003000600002 |
dc.identifier.issn.none.fl_str_mv |
0100-879X |
dc.identifier.file.none.fl_str_mv |
S0100-879X2003000600002.pdf |
dc.identifier.scielo.none.fl_str_mv |
S0100-879X2003000600002 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-879X2003000600002 |
dc.identifier.wos.none.fl_str_mv |
WOS:000183866400002 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 36, n. 6, p. 693-697, 2003. 0100-879X S0100-879X2003000600002.pdf S0100-879X2003000600002 10.1590/S0100-879X2003000600002 WOS:000183866400002 |
url |
http://repositorio.unifesp.br/handle/11600/1719 http://dx.doi.org/10.1590/S0100-879X2003000600002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
693-697 |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
bitstream.url.fl_str_mv |
${dspace.ui.url}/bitstream/11600/1719/1/S0100-879X2003000600002.pdf ${dspace.ui.url}/bitstream/11600/1719/21/S0100-879X2003000600002.pdf.txt ${dspace.ui.url}/bitstream/11600/1719/23/S0100-879X2003000600002.pdf.jpg |
bitstream.checksum.fl_str_mv |
47eb81b648c51858c7f3fc79549ce79d 1a11278db5192bd33ae40a1b4b492a53 6375795a8f7658813b93bd7b61c762d6 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1783460286336860160 |