Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise

Detalhes bibliográficos
Autor(a) principal: Melo, Stéphano Freitas Soares
Data de Publicação: 2008
Outros Autores: Lunz, Wellington, Fontes, Elizabeth Pacheco Batista, Dias, Cristina Maria Ganns Chaves, Moura, Anselmo Gomes de, Carlo, Ricardo Junqueira Del, Natali, Antonio Jose, Carneiro Júnior, Miguel Araujo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: LOCUS Repositório Institucional da UFV
Texto Completo: http://dx.doi.org/10.1590/S0066-782X2009001100004
http://www.locus.ufv.br/handle/123456789/12504
Resumo: Physical exercise induces hemodynamic stress. To evaluate if voluntary running and forced running induced different levels of stress protein (Hsp72) in the myocardium of female Wistar rats. Female rats were randomly assigned to the following groups: forced treadmill running group (FR; n= 6), voluntary running group (VR; n=6) and control group (C; n=6). VR group animals had free access to running wheels, and those from FR group underwent a running program on a treadmill (18 m/min, 60 min/day, 5 days/wk) for 8 weeks. Left ventricle (LV) and right ventricle (RV) fragments were collected at sacrifice, and the relative immunoblot contents of stress protein (Hsp72) were determined. VR animals ran on average 4.87 km/wk, and FR rats ran 4.88 km/wk. Animals from VR and FR groups had less body weight gain (p<0.05) than those from C group (81.67 ± 11.95g vs 81.17 ± 10.18g vs 111.50 ± 2.26g, respectively). Heart weight/body weight ratio was not significantly different (p>0.05) among VR, FR and C groups (4.54 ± 0.79 mg/g vs 4.94 ± 0.89 mg/g vs 4.34 ± 0.87 mg/g, respectively). FR group animals had levels of Hsp72 (p<0.05) higher than those from VR, both in LV (287.45 ± 35.86 % vs 135.59 ± 5.10 %, respectively) and RV (241.31 ± 25.83 % vs 137.91 ± 45.20 %, respectively). Voluntary running and forced running induced different levels of Hsp72 in the myocardium of female Wistar rats.
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spelling Melo, Stéphano Freitas SoaresLunz, WellingtonFontes, Elizabeth Pacheco BatistaDias, Cristina Maria Ganns ChavesMoura, Anselmo Gomes deCarlo, Ricardo Junqueira DelNatali, Antonio JoseCarneiro Júnior, Miguel Araujo2017-10-30T14:15:56Z2017-10-30T14:15:56Z2008-12-020066-782Xhttp://dx.doi.org/10.1590/S0066-782X2009001100004http://www.locus.ufv.br/handle/123456789/12504Physical exercise induces hemodynamic stress. To evaluate if voluntary running and forced running induced different levels of stress protein (Hsp72) in the myocardium of female Wistar rats. Female rats were randomly assigned to the following groups: forced treadmill running group (FR; n= 6), voluntary running group (VR; n=6) and control group (C; n=6). VR group animals had free access to running wheels, and those from FR group underwent a running program on a treadmill (18 m/min, 60 min/day, 5 days/wk) for 8 weeks. Left ventricle (LV) and right ventricle (RV) fragments were collected at sacrifice, and the relative immunoblot contents of stress protein (Hsp72) were determined. VR animals ran on average 4.87 km/wk, and FR rats ran 4.88 km/wk. Animals from VR and FR groups had less body weight gain (p<0.05) than those from C group (81.67 ± 11.95g vs 81.17 ± 10.18g vs 111.50 ± 2.26g, respectively). Heart weight/body weight ratio was not significantly different (p>0.05) among VR, FR and C groups (4.54 ± 0.79 mg/g vs 4.94 ± 0.89 mg/g vs 4.34 ± 0.87 mg/g, respectively). FR group animals had levels of Hsp72 (p<0.05) higher than those from VR, both in LV (287.45 ± 35.86 % vs 135.59 ± 5.10 %, respectively) and RV (241.31 ± 25.83 % vs 137.91 ± 45.20 %, respectively). Voluntary running and forced running induced different levels of Hsp72 in the myocardium of female Wistar rats.engArquivos Brasileiros de Cardiologia93(5), p. 423-429, 2009Physical activityRunningRatsStressMyocardiumDifferent levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exerciseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfinfo:eu-repo/semantics/openAccessreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALen_a04v93n5.pdfen_a04v93n5.pdftexto completoapplication/pdf484453https://locus.ufv.br//bitstream/123456789/12504/1/en_a04v93n5.pdf7a9f3d994188cc02b4d58968fe78da85MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://locus.ufv.br//bitstream/123456789/12504/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILen_a04v93n5.pdf.jpgen_a04v93n5.pdf.jpgIM Thumbnailimage/jpeg4719https://locus.ufv.br//bitstream/123456789/12504/3/en_a04v93n5.pdf.jpg00cb8d1e07fae6aad50894a61982d000MD53123456789/125042017-10-30 22:00:28.132oai:locus.ufv.br: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Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452017-10-31T01:00:28LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false
dc.title.en.fl_str_mv Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
title Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
spellingShingle Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
Melo, Stéphano Freitas Soares
Physical activity
Running
Rats
Stress
Myocardium
title_short Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
title_full Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
title_fullStr Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
title_full_unstemmed Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
title_sort Different levels of Hsp72 in female rat myocardium in response to voluntary exercise and forced exercise
author Melo, Stéphano Freitas Soares
author_facet Melo, Stéphano Freitas Soares
Lunz, Wellington
Fontes, Elizabeth Pacheco Batista
Dias, Cristina Maria Ganns Chaves
Moura, Anselmo Gomes de
Carlo, Ricardo Junqueira Del
Natali, Antonio Jose
Carneiro Júnior, Miguel Araujo
author_role author
author2 Lunz, Wellington
Fontes, Elizabeth Pacheco Batista
Dias, Cristina Maria Ganns Chaves
Moura, Anselmo Gomes de
Carlo, Ricardo Junqueira Del
Natali, Antonio Jose
Carneiro Júnior, Miguel Araujo
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo, Stéphano Freitas Soares
Lunz, Wellington
Fontes, Elizabeth Pacheco Batista
Dias, Cristina Maria Ganns Chaves
Moura, Anselmo Gomes de
Carlo, Ricardo Junqueira Del
Natali, Antonio Jose
Carneiro Júnior, Miguel Araujo
dc.subject.pt-BR.fl_str_mv Physical activity
Running
Rats
Stress
Myocardium
topic Physical activity
Running
Rats
Stress
Myocardium
description Physical exercise induces hemodynamic stress. To evaluate if voluntary running and forced running induced different levels of stress protein (Hsp72) in the myocardium of female Wistar rats. Female rats were randomly assigned to the following groups: forced treadmill running group (FR; n= 6), voluntary running group (VR; n=6) and control group (C; n=6). VR group animals had free access to running wheels, and those from FR group underwent a running program on a treadmill (18 m/min, 60 min/day, 5 days/wk) for 8 weeks. Left ventricle (LV) and right ventricle (RV) fragments were collected at sacrifice, and the relative immunoblot contents of stress protein (Hsp72) were determined. VR animals ran on average 4.87 km/wk, and FR rats ran 4.88 km/wk. Animals from VR and FR groups had less body weight gain (p<0.05) than those from C group (81.67 ± 11.95g vs 81.17 ± 10.18g vs 111.50 ± 2.26g, respectively). Heart weight/body weight ratio was not significantly different (p>0.05) among VR, FR and C groups (4.54 ± 0.79 mg/g vs 4.94 ± 0.89 mg/g vs 4.34 ± 0.87 mg/g, respectively). FR group animals had levels of Hsp72 (p<0.05) higher than those from VR, both in LV (287.45 ± 35.86 % vs 135.59 ± 5.10 %, respectively) and RV (241.31 ± 25.83 % vs 137.91 ± 45.20 %, respectively). Voluntary running and forced running induced different levels of Hsp72 in the myocardium of female Wistar rats.
publishDate 2008
dc.date.issued.fl_str_mv 2008-12-02
dc.date.accessioned.fl_str_mv 2017-10-30T14:15:56Z
dc.date.available.fl_str_mv 2017-10-30T14:15:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0066-782X2009001100004
http://www.locus.ufv.br/handle/123456789/12504
dc.identifier.issn.none.fl_str_mv 0066-782X
identifier_str_mv 0066-782X
url http://dx.doi.org/10.1590/S0066-782X2009001100004
http://www.locus.ufv.br/handle/123456789/12504
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartofseries.pt-BR.fl_str_mv 93(5), p. 423-429, 2009
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publisher.none.fl_str_mv Arquivos Brasileiros de Cardiologia
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