Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis

Detalhes bibliográficos
Autor(a) principal: Silva, Luciana Saraiva da
Data de Publicação: 2015
Outros Autores: Cotta, Rosângela Minardi Mitre, Moreira, Tiago Ricardo, Silva, Rodrigo Gomes da, Rosa, Carla de Oliveira Barbosa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: LOCUS Repositório Institucional da UFV
Texto Completo: https://doi.org/10.1007/s10389-015-0674-7
http://www.locus.ufv.br/handle/123456789/24030
Resumo: The prevalence of chronic kidney disease (CKD) has been increasing worldwide. In practice, the glomerular filtration rate (GFR) can be assessed by the dosage of creatinine serum, its clearance through the kidneys and estimation formulae. However, there is no existing consensus about the best method of assessment; therefore, the aim of the present study is to assess the different methods of detecting CKD. A total of 293 hypertensive patients participated in the research. Creatinine serum and clearance were assessed to analyze kidney function. The GFR was estimated using the following formulae: Cockcroft and Gault (CG); CG-corrected; Modification of Diet in Renal Disease(MDRD)-6; MDRD-4 and The Chronic Kidney Disease Epidemiology Collaboration Equation(CKD-EPI). The following tests were used: weighted Kappa coefficient; Pearson’s correlation (r) and Bland-Altman graph analysis. The greatest agreement found using the weighted Kappa was for the CKD-EPI formula (k = 0.362). The greatest correlation was found for the CKD-EPI formula (r = 0.612). The CKD-EPI formula exhibited the lowest number of individuals below the lowest limit of agreement in the Bland-Altman analysis. The CKD-EPI formula should be used to estimate the GFR, given that it exhibited the greatest correlation and agreement with creatinine clearance; thus, it is possible to implement low-cost activities focusing on early detection and diagnosis, as well as the prevention of CKD.
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spelling Silva, Luciana Saraiva daCotta, Rosângela Minardi MitreMoreira, Tiago RicardoSilva, Rodrigo Gomes daRosa, Carla de Oliveira Barbosa2019-03-20T18:09:36Z2019-03-20T18:09:36Z2015-081613-2238https://doi.org/10.1007/s10389-015-0674-7http://www.locus.ufv.br/handle/123456789/24030The prevalence of chronic kidney disease (CKD) has been increasing worldwide. In practice, the glomerular filtration rate (GFR) can be assessed by the dosage of creatinine serum, its clearance through the kidneys and estimation formulae. However, there is no existing consensus about the best method of assessment; therefore, the aim of the present study is to assess the different methods of detecting CKD. A total of 293 hypertensive patients participated in the research. Creatinine serum and clearance were assessed to analyze kidney function. The GFR was estimated using the following formulae: Cockcroft and Gault (CG); CG-corrected; Modification of Diet in Renal Disease(MDRD)-6; MDRD-4 and The Chronic Kidney Disease Epidemiology Collaboration Equation(CKD-EPI). The following tests were used: weighted Kappa coefficient; Pearson’s correlation (r) and Bland-Altman graph analysis. The greatest agreement found using the weighted Kappa was for the CKD-EPI formula (k = 0.362). The greatest correlation was found for the CKD-EPI formula (r = 0.612). The CKD-EPI formula exhibited the lowest number of individuals below the lowest limit of agreement in the Bland-Altman analysis. The CKD-EPI formula should be used to estimate the GFR, given that it exhibited the greatest correlation and agreement with creatinine clearance; thus, it is possible to implement low-cost activities focusing on early detection and diagnosis, as well as the prevention of CKD.engJournal of Public HealthVolume 23, Issue 4, Pages 223–229, August 2015Springer-Verlag Berlin Heidelberginfo:eu-repo/semantics/openAccessChronic kidney diseaseTests of kidney functionPrimary health careHypertensionDisease preventionAssessment of different detection methods of chronic kidney disease and their importance for an early diagnosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALartigo.pdfartigo.pdfTexto completoapplication/pdf740349https://locus.ufv.br//bitstream/123456789/24030/1/artigo.pdfd7e9207d7c79eb30b8fe5f88a3d3905aMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://locus.ufv.br//bitstream/123456789/24030/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/240302019-03-20 15:18:08.629oai:locus.ufv.br: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Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452019-03-20T18:18:08LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false
dc.title.en.fl_str_mv Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
title Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
spellingShingle Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
Silva, Luciana Saraiva da
Chronic kidney disease
Tests of kidney function
Primary health care
Hypertension
Disease prevention
title_short Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
title_full Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
title_fullStr Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
title_full_unstemmed Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
title_sort Assessment of different detection methods of chronic kidney disease and their importance for an early diagnosis
author Silva, Luciana Saraiva da
author_facet Silva, Luciana Saraiva da
Cotta, Rosângela Minardi Mitre
Moreira, Tiago Ricardo
Silva, Rodrigo Gomes da
Rosa, Carla de Oliveira Barbosa
author_role author
author2 Cotta, Rosângela Minardi Mitre
Moreira, Tiago Ricardo
Silva, Rodrigo Gomes da
Rosa, Carla de Oliveira Barbosa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Luciana Saraiva da
Cotta, Rosângela Minardi Mitre
Moreira, Tiago Ricardo
Silva, Rodrigo Gomes da
Rosa, Carla de Oliveira Barbosa
dc.subject.pt-BR.fl_str_mv Chronic kidney disease
Tests of kidney function
Primary health care
Hypertension
Disease prevention
topic Chronic kidney disease
Tests of kidney function
Primary health care
Hypertension
Disease prevention
description The prevalence of chronic kidney disease (CKD) has been increasing worldwide. In practice, the glomerular filtration rate (GFR) can be assessed by the dosage of creatinine serum, its clearance through the kidneys and estimation formulae. However, there is no existing consensus about the best method of assessment; therefore, the aim of the present study is to assess the different methods of detecting CKD. A total of 293 hypertensive patients participated in the research. Creatinine serum and clearance were assessed to analyze kidney function. The GFR was estimated using the following formulae: Cockcroft and Gault (CG); CG-corrected; Modification of Diet in Renal Disease(MDRD)-6; MDRD-4 and The Chronic Kidney Disease Epidemiology Collaboration Equation(CKD-EPI). The following tests were used: weighted Kappa coefficient; Pearson’s correlation (r) and Bland-Altman graph analysis. The greatest agreement found using the weighted Kappa was for the CKD-EPI formula (k = 0.362). The greatest correlation was found for the CKD-EPI formula (r = 0.612). The CKD-EPI formula exhibited the lowest number of individuals below the lowest limit of agreement in the Bland-Altman analysis. The CKD-EPI formula should be used to estimate the GFR, given that it exhibited the greatest correlation and agreement with creatinine clearance; thus, it is possible to implement low-cost activities focusing on early detection and diagnosis, as well as the prevention of CKD.
publishDate 2015
dc.date.issued.fl_str_mv 2015-08
dc.date.accessioned.fl_str_mv 2019-03-20T18:09:36Z
dc.date.available.fl_str_mv 2019-03-20T18:09:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.1007/s10389-015-0674-7
http://www.locus.ufv.br/handle/123456789/24030
dc.identifier.issn.none.fl_str_mv 1613-2238
identifier_str_mv 1613-2238
url https://doi.org/10.1007/s10389-015-0674-7
http://www.locus.ufv.br/handle/123456789/24030
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartofseries.pt-BR.fl_str_mv Volume 23, Issue 4, Pages 223–229, August 2015
dc.rights.driver.fl_str_mv Springer-Verlag Berlin Heidelberg
info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Journal of Public Health
publisher.none.fl_str_mv Journal of Public Health
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