Kinetics of rabies antibodies as a strategy for canine active immunization

Detalhes bibliográficos
Autor(a) principal: Babboni,Selene Daniela
Data de Publicação: 2014
Outros Autores: Costa,Hení Falcão da, Martorelli,Luzia de Fátima Alves, Kataoka,Ana Paula de Arruda Geraldes, Victoria,Cassiano, Padovani,Carlos Roberto, Modolo,José Rafael
Tipo de documento: Artigo
Idioma: eng
Título da fonte: The Journal of venomous animals and toxins including tropical diseases (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200602
Resumo: Background Rabies, a zoonosis found throughout the globe, is caused by a virus of theLyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palácios modified vaccine in the urban area of Botucatu city, São Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (≥0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period.Conclusions The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months.
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spelling Kinetics of rabies antibodies as a strategy for canine active immunizationRabiesDogsVaccinationRevaccinationAnnual vaccination campaignFuenzalida-PaláciosBackground Rabies, a zoonosis found throughout the globe, is caused by a virus of theLyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palácios modified vaccine in the urban area of Botucatu city, São Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (≥0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period.Conclusions The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months.Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200602Journal of Venomous Animals and Toxins including Tropical Diseases v.20 2014reponame:The Journal of venomous animals and toxins including tropical diseases (Online)instname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1186/1678-9199-20-37info:eu-repo/semantics/openAccessBabboni,Selene DanielaCosta,Hení Falcão daMartorelli,Luzia de Fátima AlvesKataoka,Ana Paula de Arruda GeraldesVictoria,CassianoPadovani,Carlos RobertoModolo,José Rafaeleng2018-08-17T00:00:00Zoai:scielo:S1678-91992014000200602Revistahttp://www.scielo.br/jvatitdPUBhttps://old.scielo.br/oai/scielo-oai.php||editorial@jvat.org.br1678-91991678-9180opendoar:2018-08-17T00:00The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Kinetics of rabies antibodies as a strategy for canine active immunization
title Kinetics of rabies antibodies as a strategy for canine active immunization
spellingShingle Kinetics of rabies antibodies as a strategy for canine active immunization
Babboni,Selene Daniela
Rabies
Dogs
Vaccination
Revaccination
Annual vaccination campaign
Fuenzalida-Palácios
title_short Kinetics of rabies antibodies as a strategy for canine active immunization
title_full Kinetics of rabies antibodies as a strategy for canine active immunization
title_fullStr Kinetics of rabies antibodies as a strategy for canine active immunization
title_full_unstemmed Kinetics of rabies antibodies as a strategy for canine active immunization
title_sort Kinetics of rabies antibodies as a strategy for canine active immunization
author Babboni,Selene Daniela
author_facet Babboni,Selene Daniela
Costa,Hení Falcão da
Martorelli,Luzia de Fátima Alves
Kataoka,Ana Paula de Arruda Geraldes
Victoria,Cassiano
Padovani,Carlos Roberto
Modolo,José Rafael
author_role author
author2 Costa,Hení Falcão da
Martorelli,Luzia de Fátima Alves
Kataoka,Ana Paula de Arruda Geraldes
Victoria,Cassiano
Padovani,Carlos Roberto
Modolo,José Rafael
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Babboni,Selene Daniela
Costa,Hení Falcão da
Martorelli,Luzia de Fátima Alves
Kataoka,Ana Paula de Arruda Geraldes
Victoria,Cassiano
Padovani,Carlos Roberto
Modolo,José Rafael
dc.subject.por.fl_str_mv Rabies
Dogs
Vaccination
Revaccination
Annual vaccination campaign
Fuenzalida-Palácios
topic Rabies
Dogs
Vaccination
Revaccination
Annual vaccination campaign
Fuenzalida-Palácios
description Background Rabies, a zoonosis found throughout the globe, is caused by a virus of theLyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palácios modified vaccine in the urban area of Botucatu city, São Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (≥0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period.Conclusions The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200602
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200602
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1186/1678-9199-20-37
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)
dc.source.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases v.20 2014
reponame:The Journal of venomous animals and toxins including tropical diseases (Online)
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str The Journal of venomous animals and toxins including tropical diseases (Online)
collection The Journal of venomous animals and toxins including tropical diseases (Online)
repository.name.fl_str_mv The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv ||editorial@jvat.org.br
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