Heparan sulfate and cell division

Detalhes bibliográficos
Autor(a) principal: Porcionatto,M.A.
Data de Publicação: 1999
Outros Autores: Nader,H.B., Dietrich,C.P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500006
Resumo: Heparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic transformation. Several lines of experimental evidence suggest that heparan sulfate plays a role in cellular recognition, cellular adhesion and growth control. Heparan sulfate can participate in the process of cell division in two distinct ways, either as a positive or negative modulator of cellular proliferation, or as a response to a mitogenic stimulus.
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spelling Heparan sulfate and cell divisionheparan sulfateglycosaminoglycanproteoglycancell divisioncell cyclegrowth factorsHeparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic transformation. Several lines of experimental evidence suggest that heparan sulfate plays a role in cellular recognition, cellular adhesion and growth control. Heparan sulfate can participate in the process of cell division in two distinct ways, either as a positive or negative modulator of cellular proliferation, or as a response to a mitogenic stimulus.Associação Brasileira de Divulgação Científica1999-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500006Brazilian Journal of Medical and Biological Research v.32 n.5 1999reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X1999000500006info:eu-repo/semantics/openAccessPorcionatto,M.A.Nader,H.B.Dietrich,C.P.eng1999-04-27T00:00:00Zoai:scielo:S0100-879X1999000500006Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:1999-04-27T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Heparan sulfate and cell division
title Heparan sulfate and cell division
spellingShingle Heparan sulfate and cell division
Porcionatto,M.A.
heparan sulfate
glycosaminoglycan
proteoglycan
cell division
cell cycle
growth factors
title_short Heparan sulfate and cell division
title_full Heparan sulfate and cell division
title_fullStr Heparan sulfate and cell division
title_full_unstemmed Heparan sulfate and cell division
title_sort Heparan sulfate and cell division
author Porcionatto,M.A.
author_facet Porcionatto,M.A.
Nader,H.B.
Dietrich,C.P.
author_role author
author2 Nader,H.B.
Dietrich,C.P.
author2_role author
author
dc.contributor.author.fl_str_mv Porcionatto,M.A.
Nader,H.B.
Dietrich,C.P.
dc.subject.por.fl_str_mv heparan sulfate
glycosaminoglycan
proteoglycan
cell division
cell cycle
growth factors
topic heparan sulfate
glycosaminoglycan
proteoglycan
cell division
cell cycle
growth factors
description Heparan sulfate is a component of vertebrate and invertebrate tissues which appears during the cytodifferentiation stage of embryonic development. Its structure varies according to the tissue and species of origin and is modified during neoplastic transformation. Several lines of experimental evidence suggest that heparan sulfate plays a role in cellular recognition, cellular adhesion and growth control. Heparan sulfate can participate in the process of cell division in two distinct ways, either as a positive or negative modulator of cellular proliferation, or as a response to a mitogenic stimulus.
publishDate 1999
dc.date.none.fl_str_mv 1999-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X1999000500006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.32 n.5 1999
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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