Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista brasileira de hematologia e hemoterapia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842007000400020 |
Resumo: | In spite of the development of pharmacological strategies, technology and more sophisticated surgical alternatives, incidences of death from cardiopathies remains high throughout the world, in particular in relation to dilated heart disease. Many of these patients benefit from recent strategies of early myocardial perfusion which significantly reduces mortality rates; even so past-infarction heart failure is common. Recent studies have shown that the infusion of autologous stem cells is a possible treatment to reverse ventricular dysfunction. However, frequently there is an associated electrical conduction defect. Thus, an infusion of stem cells may produce a mechanical correction with heart resynchronization correcting the electrical conduction defect thereby improving the left ventricle ejection fraction. Our institution has been combining stem cell transplantation with resynchronization and, when necessary, cardiofibrilation, to treat these patients giving improvements in the Functional Class, ejection fraction and left ventricle and right ventricle-left ventricle synchrony. |
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Revista brasileira de hematologia e hemoterapia (Online) |
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Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificialDilated heart diseasestem cell transplantationheart resynchronizationmyocardial infarctionIn spite of the development of pharmacological strategies, technology and more sophisticated surgical alternatives, incidences of death from cardiopathies remains high throughout the world, in particular in relation to dilated heart disease. Many of these patients benefit from recent strategies of early myocardial perfusion which significantly reduces mortality rates; even so past-infarction heart failure is common. Recent studies have shown that the infusion of autologous stem cells is a possible treatment to reverse ventricular dysfunction. However, frequently there is an associated electrical conduction defect. Thus, an infusion of stem cells may produce a mechanical correction with heart resynchronization correcting the electrical conduction defect thereby improving the left ventricle ejection fraction. Our institution has been combining stem cell transplantation with resynchronization and, when necessary, cardiofibrilation, to treat these patients giving improvements in the Functional Class, ejection fraction and left ventricle and right ventricle-left ventricle synchrony.Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular2007-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842007000400020Revista Brasileira de Hematologia e Hemoterapia v.29 n.4 2007reponame:Revista brasileira de hematologia e hemoterapia (Online)instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)instacron:ABHHTC10.1590/S1516-84842007000400020info:eu-repo/semantics/openAccessGreco,Oswaldo TadeuGreco,Rafael LoisAbreu,Ana Carolina depor2008-03-06T00:00:00Zoai:scielo:S1516-84842007000400020Revistahttp://www.rbhh.org/pt/archivo/https://old.scielo.br/oai/scielo-oai.phpsbhh@terra.com.br||secretaria@rbhh.org1806-08701516-8484opendoar:2008-03-06T00:00Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)false |
dc.title.none.fl_str_mv |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
title |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
spellingShingle |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial Greco,Oswaldo Tadeu Dilated heart disease stem cell transplantation heart resynchronization myocardial infarction |
title_short |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
title_full |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
title_fullStr |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
title_full_unstemmed |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
title_sort |
Uso de células-tronco no tratamento de pacientes com miocardiopatia dilatada de diferentes etiologias, associada à ressincronização cardíaca artificial |
author |
Greco,Oswaldo Tadeu |
author_facet |
Greco,Oswaldo Tadeu Greco,Rafael Lois Abreu,Ana Carolina de |
author_role |
author |
author2 |
Greco,Rafael Lois Abreu,Ana Carolina de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Greco,Oswaldo Tadeu Greco,Rafael Lois Abreu,Ana Carolina de |
dc.subject.por.fl_str_mv |
Dilated heart disease stem cell transplantation heart resynchronization myocardial infarction |
topic |
Dilated heart disease stem cell transplantation heart resynchronization myocardial infarction |
description |
In spite of the development of pharmacological strategies, technology and more sophisticated surgical alternatives, incidences of death from cardiopathies remains high throughout the world, in particular in relation to dilated heart disease. Many of these patients benefit from recent strategies of early myocardial perfusion which significantly reduces mortality rates; even so past-infarction heart failure is common. Recent studies have shown that the infusion of autologous stem cells is a possible treatment to reverse ventricular dysfunction. However, frequently there is an associated electrical conduction defect. Thus, an infusion of stem cells may produce a mechanical correction with heart resynchronization correcting the electrical conduction defect thereby improving the left ventricle ejection fraction. Our institution has been combining stem cell transplantation with resynchronization and, when necessary, cardiofibrilation, to treat these patients giving improvements in the Functional Class, ejection fraction and left ventricle and right ventricle-left ventricle synchrony. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842007000400020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842007000400020 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.1590/S1516-84842007000400020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular |
publisher.none.fl_str_mv |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular |
dc.source.none.fl_str_mv |
Revista Brasileira de Hematologia e Hemoterapia v.29 n.4 2007 reponame:Revista brasileira de hematologia e hemoterapia (Online) instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) instacron:ABHHTC |
instname_str |
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) |
instacron_str |
ABHHTC |
institution |
ABHHTC |
reponame_str |
Revista brasileira de hematologia e hemoterapia (Online) |
collection |
Revista brasileira de hematologia e hemoterapia (Online) |
repository.name.fl_str_mv |
Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) |
repository.mail.fl_str_mv |
sbhh@terra.com.br||secretaria@rbhh.org |
_version_ |
1754213108696481792 |