45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Materials research (São Carlos. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000100214 |
Resumo: | Scaffolds of bioglass derived from BG45S5 (45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O and 6 wt% P2O5) containing 10 wt% niobium were prepared by gelcasting method. The scaffolds presented a 3D porous structure with interconnected and spherical pores (pore size range 100 μm to 500 μm) and high porosity (89%), similar to trabecular architecture of spongy bone. The compressive strength was 0.18 ± 0.03 MPa which is acceptable for bone repair applications. The in vitro biological studies showed cytocompatibility for human osteoblastic cells as well tendency for higher alkaline phosphatase activity. Therefore, the findings here suggest the great potential of the scaffolds for using in bone tissue engineering. |
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45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting MethodBioglass, Niobium oxide, ScaffoldGelcasting method, Porous materials, Bone tissue engineeringScaffolds of bioglass derived from BG45S5 (45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O and 6 wt% P2O5) containing 10 wt% niobium were prepared by gelcasting method. The scaffolds presented a 3D porous structure with interconnected and spherical pores (pore size range 100 μm to 500 μm) and high porosity (89%), similar to trabecular architecture of spongy bone. The compressive strength was 0.18 ± 0.03 MPa which is acceptable for bone repair applications. The in vitro biological studies showed cytocompatibility for human osteoblastic cells as well tendency for higher alkaline phosphatase activity. Therefore, the findings here suggest the great potential of the scaffolds for using in bone tissue engineering.ABM, ABC, ABPol2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000100214Materials Research v.24 n.1 2021reponame:Materials research (São Carlos. Online)instname:Universidade Federal de São Carlos (UFSCAR)instacron:ABM ABC ABPOL10.1590/1980-5373-mr-2020-0403info:eu-repo/semantics/openAccessSiqueira,Lilian deGrenho,LilianaFernandes,Maria H.Monteiro,Fernando J.Trichês,Eliandra S.eng2021-02-01T00:00:00Zoai:scielo:S1516-14392021000100214Revistahttp://www.scielo.br/mrPUBhttps://old.scielo.br/oai/scielo-oai.phpdedz@power.ufscar.br1980-53731516-1439opendoar:2021-02-01T00:00Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR)false |
dc.title.none.fl_str_mv |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
title |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
spellingShingle |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method Siqueira,Lilian de Bioglass, Niobium oxide, Scaffold Gelcasting method, Porous materials, Bone tissue engineering |
title_short |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
title_full |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
title_fullStr |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
title_full_unstemmed |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
title_sort |
45S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method |
author |
Siqueira,Lilian de |
author_facet |
Siqueira,Lilian de Grenho,Liliana Fernandes,Maria H. Monteiro,Fernando J. Trichês,Eliandra S. |
author_role |
author |
author2 |
Grenho,Liliana Fernandes,Maria H. Monteiro,Fernando J. Trichês,Eliandra S. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Siqueira,Lilian de Grenho,Liliana Fernandes,Maria H. Monteiro,Fernando J. Trichês,Eliandra S. |
dc.subject.por.fl_str_mv |
Bioglass, Niobium oxide, Scaffold Gelcasting method, Porous materials, Bone tissue engineering |
topic |
Bioglass, Niobium oxide, Scaffold Gelcasting method, Porous materials, Bone tissue engineering |
description |
Scaffolds of bioglass derived from BG45S5 (45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O and 6 wt% P2O5) containing 10 wt% niobium were prepared by gelcasting method. The scaffolds presented a 3D porous structure with interconnected and spherical pores (pore size range 100 μm to 500 μm) and high porosity (89%), similar to trabecular architecture of spongy bone. The compressive strength was 0.18 ± 0.03 MPa which is acceptable for bone repair applications. The in vitro biological studies showed cytocompatibility for human osteoblastic cells as well tendency for higher alkaline phosphatase activity. Therefore, the findings here suggest the great potential of the scaffolds for using in bone tissue engineering. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000100214 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392021000100214 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1980-5373-mr-2020-0403 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABM, ABC, ABPol |
publisher.none.fl_str_mv |
ABM, ABC, ABPol |
dc.source.none.fl_str_mv |
Materials Research v.24 n.1 2021 reponame:Materials research (São Carlos. Online) instname:Universidade Federal de São Carlos (UFSCAR) instacron:ABM ABC ABPOL |
instname_str |
Universidade Federal de São Carlos (UFSCAR) |
instacron_str |
ABM ABC ABPOL |
institution |
ABM ABC ABPOL |
reponame_str |
Materials research (São Carlos. Online) |
collection |
Materials research (São Carlos. Online) |
repository.name.fl_str_mv |
Materials research (São Carlos. Online) - Universidade Federal de São Carlos (UFSCAR) |
repository.mail.fl_str_mv |
dedz@power.ufscar.br |
_version_ |
1754212678115524608 |