Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000900671 |
Resumo: | Objective To assess cognition in major depressed (MD), Alzheimer's disease (AD), and depression in AD elderly. Method Subjects were evaluated by Mini Mental, Rey Auditory Verbal Learning Test, Rey Complex Figure, Digit Span, Similarities, Trail Making A/B, Verbal Fluency and Stroop. One-way ANOVA and multivariate models were used to compare the performance of each group on neuropsychological tests. Results We evaluated 212 subjects. Compared to MD, attention, working memory, processing speed and recall showed significantly better in controls. Controls showed significantly higher performance in all cognitive measures, except in attention compared to AD. Verbal fluency, memory, processing speed and abstract reasoning in MD was significantly higher compared to AD. AD was significantly better in general cognitive state than depression in AD. All other cognitive domains were similar. Conclusion A decreasing gradient in cognition appeared from the control to depression in AD, with MD and AD in an intermediate position. |
id |
ABNEURO-1_8afb9c57fc0e813a734becf9e36ff9f0 |
---|---|
oai_identifier_str |
oai:scielo:S0004-282X2014000900671 |
network_acronym_str |
ABNEURO-1 |
network_name_str |
Arquivos de neuro-psiquiatria (Online) |
repository_id_str |
|
spelling |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in ADAlzheimer?s diseasedepressionneuropsychological tests and cognition Objective To assess cognition in major depressed (MD), Alzheimer's disease (AD), and depression in AD elderly. Method Subjects were evaluated by Mini Mental, Rey Auditory Verbal Learning Test, Rey Complex Figure, Digit Span, Similarities, Trail Making A/B, Verbal Fluency and Stroop. One-way ANOVA and multivariate models were used to compare the performance of each group on neuropsychological tests. Results We evaluated 212 subjects. Compared to MD, attention, working memory, processing speed and recall showed significantly better in controls. Controls showed significantly higher performance in all cognitive measures, except in attention compared to AD. Verbal fluency, memory, processing speed and abstract reasoning in MD was significantly higher compared to AD. AD was significantly better in general cognitive state than depression in AD. All other cognitive domains were similar. Conclusion A decreasing gradient in cognition appeared from the control to depression in AD, with MD and AD in an intermediate position. Academia Brasileira de Neurologia - ABNEURO2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000900671Arquivos de Neuro-Psiquiatria v.72 n.9 2014reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20140108info:eu-repo/semantics/openAccessAraujo,Narahyana Bom deMoraes,Helena SalesSilveira,HeitorArcoverde,CynthiaVasques,Paulo EduardoBarca,Maria LageKnapskog,Anne-BritaEngedal,KnutCoutinho,Evandro Silva FreireDeslandes,Andrea CamazLaks,Jersoneng2014-09-16T00:00:00Zoai:scielo:S0004-282X2014000900671Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2014-09-16T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
title |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
spellingShingle |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD Araujo,Narahyana Bom de Alzheimer?s disease depression neuropsychological tests and cognition |
title_short |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
title_full |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
title_fullStr |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
title_full_unstemmed |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
title_sort |
Impaired cognition in depression and Alzheimer (AD): a gradient from depression to depression in AD |
author |
Araujo,Narahyana Bom de |
author_facet |
Araujo,Narahyana Bom de Moraes,Helena Sales Silveira,Heitor Arcoverde,Cynthia Vasques,Paulo Eduardo Barca,Maria Lage Knapskog,Anne-Brita Engedal,Knut Coutinho,Evandro Silva Freire Deslandes,Andrea Camaz Laks,Jerson |
author_role |
author |
author2 |
Moraes,Helena Sales Silveira,Heitor Arcoverde,Cynthia Vasques,Paulo Eduardo Barca,Maria Lage Knapskog,Anne-Brita Engedal,Knut Coutinho,Evandro Silva Freire Deslandes,Andrea Camaz Laks,Jerson |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Araujo,Narahyana Bom de Moraes,Helena Sales Silveira,Heitor Arcoverde,Cynthia Vasques,Paulo Eduardo Barca,Maria Lage Knapskog,Anne-Brita Engedal,Knut Coutinho,Evandro Silva Freire Deslandes,Andrea Camaz Laks,Jerson |
dc.subject.por.fl_str_mv |
Alzheimer?s disease depression neuropsychological tests and cognition |
topic |
Alzheimer?s disease depression neuropsychological tests and cognition |
description |
Objective To assess cognition in major depressed (MD), Alzheimer's disease (AD), and depression in AD elderly. Method Subjects were evaluated by Mini Mental, Rey Auditory Verbal Learning Test, Rey Complex Figure, Digit Span, Similarities, Trail Making A/B, Verbal Fluency and Stroop. One-way ANOVA and multivariate models were used to compare the performance of each group on neuropsychological tests. Results We evaluated 212 subjects. Compared to MD, attention, working memory, processing speed and recall showed significantly better in controls. Controls showed significantly higher performance in all cognitive measures, except in attention compared to AD. Verbal fluency, memory, processing speed and abstract reasoning in MD was significantly higher compared to AD. AD was significantly better in general cognitive state than depression in AD. All other cognitive domains were similar. Conclusion A decreasing gradient in cognition appeared from the control to depression in AD, with MD and AD in an intermediate position. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000900671 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000900671 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20140108 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.72 n.9 2014 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212777028747264 |