Progressive supranuclear palsy: new concepts

Detalhes bibliográficos
Autor(a) principal: Barsottini,Orlando Graziani Povoas
Data de Publicação: 2010
Outros Autores: Felício,André Carvalho, Aquino,Camila Catherine Henriques de, Pedroso,José Luiz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600020
Resumo: Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum, oculomotor nucleus, medulla and dentate nucleus. Over the last decade many lines of investigations have helped refine PSP in many aspects and it is the purpose of this review to help neurologists identify PSP, to better understand its pathophysiology and to provide a more focused, symptom-based treatment approach.
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spelling Progressive supranuclear palsy: new conceptsprogressive supranuclear palsyatypical parkinsonismtauopathyProgressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum, oculomotor nucleus, medulla and dentate nucleus. Over the last decade many lines of investigations have helped refine PSP in many aspects and it is the purpose of this review to help neurologists identify PSP, to better understand its pathophysiology and to provide a more focused, symptom-based treatment approach.Academia Brasileira de Neurologia - ABNEURO2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600020Arquivos de Neuro-Psiquiatria v.68 n.6 2010reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2010000600020info:eu-repo/semantics/openAccessBarsottini,Orlando Graziani PovoasFelício,André CarvalhoAquino,Camila Catherine Henriques dePedroso,José Luizeng2011-01-06T00:00:00Zoai:scielo:S0004-282X2010000600020Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2011-01-06T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Progressive supranuclear palsy: new concepts
title Progressive supranuclear palsy: new concepts
spellingShingle Progressive supranuclear palsy: new concepts
Barsottini,Orlando Graziani Povoas
progressive supranuclear palsy
atypical parkinsonism
tauopathy
title_short Progressive supranuclear palsy: new concepts
title_full Progressive supranuclear palsy: new concepts
title_fullStr Progressive supranuclear palsy: new concepts
title_full_unstemmed Progressive supranuclear palsy: new concepts
title_sort Progressive supranuclear palsy: new concepts
author Barsottini,Orlando Graziani Povoas
author_facet Barsottini,Orlando Graziani Povoas
Felício,André Carvalho
Aquino,Camila Catherine Henriques de
Pedroso,José Luiz
author_role author
author2 Felício,André Carvalho
Aquino,Camila Catherine Henriques de
Pedroso,José Luiz
author2_role author
author
author
dc.contributor.author.fl_str_mv Barsottini,Orlando Graziani Povoas
Felício,André Carvalho
Aquino,Camila Catherine Henriques de
Pedroso,José Luiz
dc.subject.por.fl_str_mv progressive supranuclear palsy
atypical parkinsonism
tauopathy
topic progressive supranuclear palsy
atypical parkinsonism
tauopathy
description Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum, oculomotor nucleus, medulla and dentate nucleus. Over the last decade many lines of investigations have helped refine PSP in many aspects and it is the purpose of this review to help neurologists identify PSP, to better understand its pathophysiology and to provide a more focused, symptom-based treatment approach.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2010000600020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.68 n.6 2010
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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