Abacavir-induced liver toxicity
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , |
| Tipo de documento: | Relatório |
| Idioma: | eng |
| Título da fonte: | Brazilian Journal of Infectious Diseases |
| Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500502 |
Resumo: | Abstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine. |
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BSID-1 |
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Brazilian Journal of Infectious Diseases |
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Abacavir-induced liver toxicityHIVAbacavirLiver toxicityAbstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.Brazilian Society of Infectious Diseases2016-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500502Brazilian Journal of Infectious Diseases v.20 n.5 2016reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1016/j.bjid.2016.03.002info:eu-repo/semantics/openAccessPezzani,Maria DilettaResnati,ChiaraDi Cristo,ValentinaRiva,AgostinoGervasoni,Cristinaeng2016-10-26T00:00:00Zoai:scielo:S1413-86702016000500502Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2016-10-26T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
| dc.title.none.fl_str_mv |
Abacavir-induced liver toxicity |
| title |
Abacavir-induced liver toxicity |
| spellingShingle |
Abacavir-induced liver toxicity Pezzani,Maria Diletta HIV Abacavir Liver toxicity |
| title_short |
Abacavir-induced liver toxicity |
| title_full |
Abacavir-induced liver toxicity |
| title_fullStr |
Abacavir-induced liver toxicity |
| title_full_unstemmed |
Abacavir-induced liver toxicity |
| title_sort |
Abacavir-induced liver toxicity |
| author |
Pezzani,Maria Diletta |
| author_facet |
Pezzani,Maria Diletta Resnati,Chiara Di Cristo,Valentina Riva,Agostino Gervasoni,Cristina |
| author_role |
author |
| author2 |
Resnati,Chiara Di Cristo,Valentina Riva,Agostino Gervasoni,Cristina |
| author2_role |
author author author author |
| dc.contributor.author.fl_str_mv |
Pezzani,Maria Diletta Resnati,Chiara Di Cristo,Valentina Riva,Agostino Gervasoni,Cristina |
| dc.subject.por.fl_str_mv |
HIV Abacavir Liver toxicity |
| topic |
HIV Abacavir Liver toxicity |
| description |
Abstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine. |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016-10-01 |
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info:eu-repo/semantics/report |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
report |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500502 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500502 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1016/j.bjid.2016.03.002 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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text/html |
| dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
| publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
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Brazilian Journal of Infectious Diseases v.20 n.5 2016 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
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Brazilian Society of Infectious Diseases (BSID) |
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BSID |
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BSID |
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Brazilian Journal of Infectious Diseases |
| collection |
Brazilian Journal of Infectious Diseases |
| repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
| repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
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1754209243792146432 |