Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/31440 |
Resumo: | Serviço Nacional de Aprendizagem Industrial–SENAI (Bahia), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB). |
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Nunes, Danielle DevequiMachado, Bruna Aparecida SouzaBarreto, Gabriele de AbreuSilva, Jéssica RebouçasSilva, Danielle Figuerêdo daRocha, José Luiz Carneiro daBrandão, Hugo NevesBorges, Valéria M.Guez, Marcelo Andres Umsza2019-02-05T17:53:22Z2019-02-05T17:53:22Z2018NUNES, D. D. et al. Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction. Plos One, v. 13, n. 12, p. 1-20, 2018.1932-6203https://www.arca.fiocruz.br/handle/icict/3144010.1371/journal.pone.0207676Serviço Nacional de Aprendizagem Industrial–SENAI (Bahia), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB).University Center. Health Institute of Technologies. National Service of Industrial Learning. Salvador, BA, Brazil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.University Center. Health Institute of Technologies. National Service of Industrial Learning. Salvador, BA, BrazilUniversity Center. Health Institute of Technologies. National Service of Industrial Learning. Salvador, BA, BrazilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.Estadual University of Feira de Santana. Feira de Santana, BA, Brazil.Estadual University of Feira de Santana. Feira de Santana, BA, Brazil.Estadual University of Feira de Santana. Feira de Santana, BA, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Salvador, BA, Brasil.Universidade Federal da Bahia. Salvador, BA, Brasil.Propolis is a natural product with many demonstrated biological activities and propolis extract has been used in the food, pharmaceutical and cosmetics industries. Different works have showed the variations in the chemical composition, and consequently, on the biological activity of the propolis that are associated with its type and geographic origin. Due to this study evaluated propolis extracts obtained through supercritical extraction and ethanolic extraction (conventional) in three samples of different types of propolis (red, green and brown), collected from different regions in Brazil (state of Bahia). Analyses were performed to determine the humidity, water activity, the content of total ash, proteins, lipids and fiber in raw propolis samples. The content of phenolic compounds, flavonoids, in vitro antioxidant activity (DPPH), catechin, ferulic acid and luteolin and antimicrobial activity against two bacteria (Staphylococcus aureus and Escherichia coli) were determined for all extracts. For the green and red ethanolic extracts the anti-leishmanicidal potential was also evaluated. The physicochemical profiles showed agreement in relation to the literature. The results identified significant differences among the extracts (p>0.05), which are in conformity with their extraction method, as well as with type and botanical origin of the samples. The extraction with supercritical fluid was not efficient to obtain extracts with the highest contents of antioxidants compounds, when compared with the ethanolic extracts. The best results were shown for the extracts obtained through the conventional extraction method (ethanolic) indicating a higher selectivity for the extraction of antioxidants compounds. The red variety showed the largest biological potential, which included the content of antioxidants compounds. The results found in this study confirm the influence of the type of the raw material on the composition and characteristics of the extracts. The parameters analysis were important to characterize and evaluate the quality of the different Brazilian propolis extracts based on the increased use of propolis by the natural products industry.engPublic Library of SciencePrópolisProdutos naturaisAção antimicrobianaPlantaAbelhasAntioxidantesPropolisNatural productsAnti-Infective AgentsPlantBeesAntioxidantChemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extractioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31440/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALDEVEQUI- NUNES, D. Chemical characterization...2018.pdfDEVEQUI- NUNES, D. Chemical characterization...2018.pdfapplication/pdf1028275https://www.arca.fiocruz.br/bitstream/icict/31440/2/DEVEQUI-%20NUNES%2c%20D.%20Chemical%20characterization...2018.pdf61748c07f0bfe86ec297d934ce14baecMD52TEXTDEVEQUI- NUNES, D. Chemical characterization...2018.pdf.txtDEVEQUI- NUNES, D. Chemical characterization...2018.pdf.txtExtracted texttext/plain79052https://www.arca.fiocruz.br/bitstream/icict/31440/3/DEVEQUI-%20NUNES%2c%20D.%20Chemical%20characterization...2018.pdf.txt2dcdb531c9114f54239f28e99471f1dbMD53icict/314402023-03-15 14:34:18.099oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:34:18Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| title |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| spellingShingle |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction Nunes, Danielle Devequi Própolis Produtos naturais Ação antimicrobiana Planta Abelhas Antioxidantes Propolis Natural products Anti-Infective Agents Plant Bees Antioxidant |
| title_short |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| title_full |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| title_fullStr |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| title_full_unstemmed |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| title_sort |
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction |
| author |
Nunes, Danielle Devequi |
| author_facet |
Nunes, Danielle Devequi Machado, Bruna Aparecida Souza Barreto, Gabriele de Abreu Silva, Jéssica Rebouças Silva, Danielle Figuerêdo da Rocha, José Luiz Carneiro da Brandão, Hugo Neves Borges, Valéria M. Guez, Marcelo Andres Umsza |
| author_role |
author |
| author2 |
Machado, Bruna Aparecida Souza Barreto, Gabriele de Abreu Silva, Jéssica Rebouças Silva, Danielle Figuerêdo da Rocha, José Luiz Carneiro da Brandão, Hugo Neves Borges, Valéria M. Guez, Marcelo Andres Umsza |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Nunes, Danielle Devequi Machado, Bruna Aparecida Souza Barreto, Gabriele de Abreu Silva, Jéssica Rebouças Silva, Danielle Figuerêdo da Rocha, José Luiz Carneiro da Brandão, Hugo Neves Borges, Valéria M. Guez, Marcelo Andres Umsza |
| dc.subject.other.pt_BR.fl_str_mv |
Própolis Produtos naturais Ação antimicrobiana Planta Abelhas Antioxidantes |
| topic |
Própolis Produtos naturais Ação antimicrobiana Planta Abelhas Antioxidantes Propolis Natural products Anti-Infective Agents Plant Bees Antioxidant |
| dc.subject.en.pt_BR.fl_str_mv |
Propolis Natural products Anti-Infective Agents Plant Bees Antioxidant |
| description |
Serviço Nacional de Aprendizagem Industrial–SENAI (Bahia), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB). |
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2018 |
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2018 |
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2019-02-05T17:53:22Z |
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2019-02-05T17:53:22Z |
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info:eu-repo/semantics/publishedVersion |
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NUNES, D. D. et al. Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction. Plos One, v. 13, n. 12, p. 1-20, 2018. |
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https://www.arca.fiocruz.br/handle/icict/31440 |
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1932-6203 |
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10.1371/journal.pone.0207676 |
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NUNES, D. D. et al. Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction. Plos One, v. 13, n. 12, p. 1-20, 2018. 1932-6203 10.1371/journal.pone.0207676 |
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