High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/59505 |
Resumo: | Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil. |
id |
CRUZ_6ef84d4aec0ca7adacaa2414a12bacd7 |
---|---|
oai_identifier_str |
oai:www.arca.fiocruz.br:icict/59505 |
network_acronym_str |
CRUZ |
network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
repository_id_str |
2135 |
spelling |
Assunção, Lucimar Gonçalves de SouzaSantos, Silvana Maria ElóiPeixoto, Sérgio William Viana2023-07-11T13:19:43Z2023-07-11T13:19:43Z2012ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012.0100-879Xhttps://www.arca.fiocruz.br/handle/icict/5950510.1590/S0100-879X2012007500154engAssociação Brasileira de Divulgação CientíficaHigh sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil / Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Propedêutica Complementar. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Enfermagem. Departamento de Enfermagem Aplicada. Belo Horizonte, MG, Brazil / Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil.The measurement of the serum concentration of the acute-phase reactant C-reactive protein (CRP) provides a useful marker in clinical practice. However, the distribution of CRP is not available for all age and population groups. This study assessed the distribution of high sensitivity CRP (hs-CRP) by gender and age in 1470 elderly individuals from a Brazilian community that participates in the Bambui Cohort Study. Blood samples were collected after 12 h of fasting and serum samples were stored at -70 degrees C. Measurements were made with a commercial hs-CRP immunonephelometric instrument. More than 50% of the results were above 3.0 mg/L for both genders. Mean hs-CRP was higher in women (3.62 +/- 2.58 mg/L) than in men (3.03 +/- 2.50 mg/L). This difference was observed for all ages, except for the over-80 age group. This is the first population-based study to describe hs-CRP values in Latin American elderly subjects. Our results indicate that significant gender differences exist in the distribution of hs-CRP, and suggest that gender-specific cut-off points for hs-CRP would be necessary for the prediction of cardiovascular risks.C-reactive proteinElderlyEpidemiologyCardiovascular riskBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALindex.pdfindex.pdfapplication/pdf163599https://www.arca.fiocruz.br/bitstream/icict/59505/2/index.pdfed4d79c2d0cf507b22e44632e373b86fMD52LICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/59505/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51icict/595052023-07-11 10:22:20.845oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-07-11T13:22:20Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.en_US.fl_str_mv |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
title |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
spellingShingle |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil Assunção, Lucimar Gonçalves de Souza C-reactive protein Elderly Epidemiology Cardiovascular risk Brazil |
title_short |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
title_full |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
title_fullStr |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
title_full_unstemmed |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
title_sort |
High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil |
author |
Assunção, Lucimar Gonçalves de Souza |
author_facet |
Assunção, Lucimar Gonçalves de Souza Santos, Silvana Maria Elói Peixoto, Sérgio William Viana |
author_role |
author |
author2 |
Santos, Silvana Maria Elói Peixoto, Sérgio William Viana |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Assunção, Lucimar Gonçalves de Souza Santos, Silvana Maria Elói Peixoto, Sérgio William Viana |
dc.subject.en.en_US.fl_str_mv |
C-reactive protein Elderly Epidemiology Cardiovascular risk Brazil |
topic |
C-reactive protein Elderly Epidemiology Cardiovascular risk Brazil |
description |
Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2023-07-11T13:19:43Z |
dc.date.available.fl_str_mv |
2023-07-11T13:19:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/59505 |
dc.identifier.issn.en_US.fl_str_mv |
0100-879X |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0100-879X2012007500154 |
identifier_str_mv |
ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012. 0100-879X 10.1590/S0100-879X2012007500154 |
url |
https://www.arca.fiocruz.br/handle/icict/59505 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/59505/2/index.pdf https://www.arca.fiocruz.br/bitstream/icict/59505/1/license.txt |
bitstream.checksum.fl_str_mv |
ed4d79c2d0cf507b22e44632e373b86f 8a4605be74aa9ea9d79846c1fba20a33 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
_version_ |
1798325055121260544 |