First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.

Detalhes bibliográficos
Autor(a) principal: Silva, Aída Cristina do Nascimento
Data de Publicação: 2011
Outros Autores: Ferrazoli, Lucilaine, Simonsen, Vera, Reis, Joice Neves, Pereira, Susan Martins, Carmo, Theomira Mauadie de Azevedo, Mota, Eduardo Luiz Andrade, Reis, Mitermayer Galvão dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5858
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Silva, Aída Cristina do NascimentoFerrazoli, LucilaineSimonsen, VeraReis, Joice NevesPereira, Susan MartinsCarmo, Theomira Mauadie de AzevedoMota, Eduardo Luiz AndradeReis, Mitermayer Galvão dos2012-11-22T21:27:22Z2012-11-22T21:27:22Z2011SILVA, A.C. et al. First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil. Cadernos de Saúde Pública, v. 27, n. 9, p. 1859-63, sep. 2011.1678-4464https://www.arca.fiocruz.br/handle/icict/5858engFirst insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilInstituto Adolfo Lutz. São Paulo, SP, BrasilInstituto Adolfo Lutz. São Paulo, SP, BrasilUniversidade Federal da Bahia. Faculdade de Farmácia. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilThis study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.Molecular EpidemiologyGenetic variationMycobacterium tuberculosisVariação GenéticaMycobacterium tuberculosis/genéticaTuberculose Pulmonar/microbiologiaAdultoDistribuição por IdadeBrasilFemininoHumanosMasculinoPolimorfismo de Fragmento de RestriçãoDistribuição por SexoTuberculose Pulmonar/genéticaAdulto Joveminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALSilva ACN First insights into the....pdfSilva ACN First insights into the....pdfapplication/pdf202435https://www.arca.fiocruz.br/bitstream/icict/5858/1/Silva%20ACN%20First%20insights%20into%20the....pdf009495b8dcb57aeebecc6e1141216837MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/5858/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTSilva ACN First insights into the....pdf.txtSilva ACN First insights into the....pdf.txtExtracted texttext/plain19207https://www.arca.fiocruz.br/bitstream/icict/5858/5/Silva%20ACN%20First%20insights%20into%20the....pdf.txt3639797734855d282e34e0b7f5b67d45MD55THUMBNAILSilva ACN First insights into the....pdf.jpgSilva ACN First insights into the....pdf.jpgGenerated Thumbnailimage/jpeg1467https://www.arca.fiocruz.br/bitstream/icict/5858/4/Silva%20ACN%20First%20insights%20into%20the....pdf.jpg267a53eade28eee49349fc166ab5555dMD54icict/58582023-03-15 14:33:15.559oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:15Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
title First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
spellingShingle First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
Silva, Aída Cristina do Nascimento
Molecular Epidemiology
Genetic variation
Mycobacterium tuberculosis
Variação Genética
Mycobacterium tuberculosis/genética
Tuberculose Pulmonar/microbiologia
Adulto
Distribuição por Idade
Brasil
Feminino
Humanos
Masculino
Polimorfismo de Fragmento de Restrição
Distribuição por Sexo
Tuberculose Pulmonar/genética
Adulto Jovem
title_short First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
title_full First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
title_fullStr First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
title_full_unstemmed First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
title_sort First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil.
author Silva, Aída Cristina do Nascimento
author_facet Silva, Aída Cristina do Nascimento
Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie de Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão dos
author_role author
author2 Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie de Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão dos
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Aída Cristina do Nascimento
Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie de Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão dos
dc.subject.en.pt_BR.fl_str_mv Molecular Epidemiology
Genetic variation
Mycobacterium tuberculosis
topic Molecular Epidemiology
Genetic variation
Mycobacterium tuberculosis
Variação Genética
Mycobacterium tuberculosis/genética
Tuberculose Pulmonar/microbiologia
Adulto
Distribuição por Idade
Brasil
Feminino
Humanos
Masculino
Polimorfismo de Fragmento de Restrição
Distribuição por Sexo
Tuberculose Pulmonar/genética
Adulto Jovem
dc.subject.decs.pt_BR.fl_str_mv Variação Genética
Mycobacterium tuberculosis/genética
Tuberculose Pulmonar/microbiologia
Adulto
Distribuição por Idade
Brasil
Feminino
Humanos
Masculino
Polimorfismo de Fragmento de Restrição
Distribuição por Sexo
Tuberculose Pulmonar/genética
Adulto Jovem
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-11-22T21:27:22Z
dc.date.available.fl_str_mv 2012-11-22T21:27:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, A.C. et al. First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil. Cadernos de Saúde Pública, v. 27, n. 9, p. 1859-63, sep. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5858
dc.identifier.issn.none.fl_str_mv 1678-4464
identifier_str_mv SILVA, A.C. et al. First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil. Cadernos de Saúde Pública, v. 27, n. 9, p. 1859-63, sep. 2011.
1678-4464
url https://www.arca.fiocruz.br/handle/icict/5858
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