Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing

Detalhes bibliográficos
Autor(a) principal: Sardi, Silvia
Data de Publicação: 2016
Outros Autores: Somasekar, Sneha, Naccache, Samia N., Bandeira, Antonio Carlos de Albuquerque, Tauro, Laura Beatriz, Campos, Gubio Soares, Chiu, Charles Y.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15155
Resumo: Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil.
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spelling Sardi, SilviaSomasekar, SnehaNaccache, Samia N.Bandeira, Antonio Carlos de AlbuquerqueTauro, Laura BeatrizCampos, Gubio SoaresChiu, Charles Y.2016-07-29T18:06:30Z2016-07-29T18:06:30Z2016SARDI, S. et al. Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, p. 1-19, Jul. 2016.0095-1137https://www.arca.fiocruz.br/handle/icict/1515510.1128/JCM.00877-16engAmerican Society for MicrobiologyCo-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencinginfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil.University of California. Department of Laboratory Medicine. San Francisco, CA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA.University of California. Department of Laboratory Medicine. San Francisco, CA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA.Hospital Aliança. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil.University of California. Department of Laboratory Medicine. San Francisco, CA, USA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA / University of California. Department of Medicine. Division of Infectious Diseases. San Francisco, CA, USA.Metagenomic next-generation sequencing (mNGS) of 15 patients with documented ZIKV infection in Bahia, Brazil from April 2015 to January 2016 identified co-infections with chikungunya virus (CHIKV) in 2 of 15 ZIKV PCR-positive cases (13.3%). While generally non-specific, the clinical presentation corresponding to these two CHIKV/ZIKV co-infections reflected infection by the virus present at higher titer. Aside from CHIKV and ZIKV, co-infections from other viral pathogens were not detected. The mNGS approach is promsiing for differential diagnosis of acute febrile illness and identification of co-infections, although targeted arbovirus screening may be sufficient in the current ZIKV outbreak setting.Chikungunya virusZika VirusVirus InfectionsArbovirusesPCRCoinfectionHumansDiagnosis, DifferentialBrazilNãoNão Publicadoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15155/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSardi S Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing.pdfSardi S Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing.pdfapplication/pdf1574367https://www.arca.fiocruz.br/bitstream/icict/15155/2/Sardi%20S%20Co-Infections%20from%20Zika%20and%20Chikungunya%20Virus%20in%20Bahia%2c%20Brazil%20Identified%20by%20Metagenomic%20Next-Generation%20Sequencing.pdf97b5a8257d6064c83c481a99031e93c5MD52TEXTSardi S Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing.pdf.txtSardi S Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing.pdf.txtExtracted texttext/plain35376https://www.arca.fiocruz.br/bitstream/icict/15155/3/Sardi%20S%20Co-Infections%20from%20Zika%20and%20Chikungunya%20Virus%20in%20Bahia%2c%20Brazil%20Identified%20by%20Metagenomic%20Next-Generation%20Sequencing.pdf.txta5a5e76fdd5387225427dca1f6c8a39aMD53icict/151552018-12-27 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dc.title.pt_BR.fl_str_mv Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
title Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
spellingShingle Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
Sardi, Silvia
Chikungunya virus
Zika Virus
Virus Infections
Arboviruses
PCR
Coinfection
Humans
Diagnosis, Differential
Brazil
title_short Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
title_full Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
title_fullStr Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
title_full_unstemmed Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
title_sort Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing
author Sardi, Silvia
author_facet Sardi, Silvia
Somasekar, Sneha
Naccache, Samia N.
Bandeira, Antonio Carlos de Albuquerque
Tauro, Laura Beatriz
Campos, Gubio Soares
Chiu, Charles Y.
author_role author
author2 Somasekar, Sneha
Naccache, Samia N.
Bandeira, Antonio Carlos de Albuquerque
Tauro, Laura Beatriz
Campos, Gubio Soares
Chiu, Charles Y.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sardi, Silvia
Somasekar, Sneha
Naccache, Samia N.
Bandeira, Antonio Carlos de Albuquerque
Tauro, Laura Beatriz
Campos, Gubio Soares
Chiu, Charles Y.
dc.subject.en.pt_BR.fl_str_mv Chikungunya virus
Zika Virus
Virus Infections
Arboviruses
PCR
Coinfection
Humans
Diagnosis, Differential
Brazil
topic Chikungunya virus
Zika Virus
Virus Infections
Arboviruses
PCR
Coinfection
Humans
Diagnosis, Differential
Brazil
description Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-07-29T18:06:30Z
dc.date.available.fl_str_mv 2016-07-29T18:06:30Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SARDI, S. et al. Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, p. 1-19, Jul. 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15155
dc.identifier.issn.pt_BR.fl_str_mv 0095-1137
dc.identifier.doi.none.fl_str_mv 10.1128/JCM.00877-16
identifier_str_mv SARDI, S. et al. Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, p. 1-19, Jul. 2016.
0095-1137
10.1128/JCM.00877-16
url https://www.arca.fiocruz.br/handle/icict/15155
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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