Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/29342 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil. |
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Simões, Rachel Siqueira de QueirozSilva, Emmanuele ParizBarth, Ortrud Monika2018-10-04T15:29:13Z2018-10-04T15:29:13Z2018SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018.2474-7637https://www.arca.fiocruz.br/handle/icict/2934210.19080/AIBM.2018.08.555749engJuniper PublishersNeoplasias do Colo do ÚteroEpidemiologiaPapillomaviridaeprevalênciaFatores preditoresCervical cancerEpidemiologyHuman papillomavirusPredictor factorsPrevalencePrevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalitiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.Universidade Itajaí. Vale do Itajaí, SC, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil.HPV is the most common sexually transmitted disease based on its oncogenic activity as high-risk (hr) types, low-risk types (lr) and types of undetermined-risk depending upon the associated diseases. The aim of this study was to evaluate the HPV infection prevalence and to identify the risk factors as demographic, behavioral and biological variables related to cervical cancer in unimmunized and sexually active women patients attended at public health institutions. A cross-sectional study conducted from 2014 to 2016 was performed at Rio de Janeiro city. All women were randomly selected and submitted to clinical and sociodemographic investigation. About 100 cervical cell scrapings were collected with a cervical cytobrush during the gynecological examination. After nucleic acid amplification directed to a conserved region of the HPV L1 gene, high-risk type specific primers (HPV16/18/31/45) were performed for genotyping. Statistical analysis was applied to analyze the risk factors associated with HPV infection in 18 sociodemographics variables obtained from informative questionnaires. This study demonstrated by the Chi-square test that of the 100 participants, 20% (95% CI: 12-28) were DNA HPV positive. HPV 18 and 45 were the most frequently detected HPV types. Most women were currently not married (56%) and married or cohabitating (44%) (p<0.05). Psychosocial and psychosexual issues demonstrated that six percent of the women exhibit history of sexually transmitted diseases, except HIV, with 85% of women having sex with until to five partners (p<0.03) and 15% used oral contraceptives, while 71% did not use any type of condom (p<0.03). A previous history of STD was not significantly related. Cytological status was without alterations in the population investigated. This paper contributed to a better understanding about the natural history of HPV from of the pre-immunization prevalence study of the active sexually and clinical free lesions women in Brazil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29342/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALortrudmonika_barth_etal_IOC_2018.pdfortrudmonika_barth_etal_IOC_2018.pdfapplication/pdf693758https://www.arca.fiocruz.br/bitstream/icict/29342/2/ortrudmonika_barth_etal_IOC_2018.pdf220f695fa564a05da6ebb744e50b8dc3MD52TEXTortrudmonika_barth_etal_IOC_2018.pdf.txtortrudmonika_barth_etal_IOC_2018.pdf.txtExtracted texttext/plain26832https://www.arca.fiocruz.br/bitstream/icict/29342/3/ortrudmonika_barth_etal_IOC_2018.pdf.txtaff7e57d8af05605c902a634e6b97c6eMD53icict/293422018-10-05 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dc.title.pt_BR.fl_str_mv |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
title |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
spellingShingle |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities Simões, Rachel Siqueira de Queiroz Neoplasias do Colo do Útero Epidemiologia Papillomaviridae prevalência Fatores preditores Cervical cancer Epidemiology Human papillomavirus Predictor factors Prevalence |
title_short |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
title_full |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
title_fullStr |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
title_full_unstemmed |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
title_sort |
Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities |
author |
Simões, Rachel Siqueira de Queiroz |
author_facet |
Simões, Rachel Siqueira de Queiroz Silva, Emmanuele Pariz Barth, Ortrud Monika |
author_role |
author |
author2 |
Silva, Emmanuele Pariz Barth, Ortrud Monika |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Simões, Rachel Siqueira de Queiroz Silva, Emmanuele Pariz Barth, Ortrud Monika |
dc.subject.other.pt_BR.fl_str_mv |
Neoplasias do Colo do Útero Epidemiologia Papillomaviridae prevalência Fatores preditores |
topic |
Neoplasias do Colo do Útero Epidemiologia Papillomaviridae prevalência Fatores preditores Cervical cancer Epidemiology Human papillomavirus Predictor factors Prevalence |
dc.subject.en.pt_BR.fl_str_mv |
Cervical cancer Epidemiology Human papillomavirus Predictor factors Prevalence |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Morfologia e Morfogênese Viral. Rio de Janeiro, RJ. Brasil. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-10-04T15:29:13Z |
dc.date.available.fl_str_mv |
2018-10-04T15:29:13Z |
dc.date.issued.fl_str_mv |
2018 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/29342 |
dc.identifier.issn.pt_BR.fl_str_mv |
2474-7637 |
dc.identifier.doi.none.fl_str_mv |
10.19080/AIBM.2018.08.555749 |
identifier_str_mv |
SIMÕES, Rachel Siqueira de Queiroz; SILVA, Emmanuele Pariz; BARTH, Ortrud Monika. Prevalence of High-Risk Human papillomavirus Genotypes and Predictors factors for Cervical Cancer in Unimmunized Brazilian Women without Cytological Abnormalities. Advances in Biotechnology & Microbiology, v.8, n.5, 7p, Mar. 2018. 2474-7637 10.19080/AIBM.2018.08.555749 |
url |
https://www.arca.fiocruz.br/handle/icict/29342 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Juniper Publishers |
publisher.none.fl_str_mv |
Juniper Publishers |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
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FIOCRUZ |
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Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
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