Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system

Detalhes bibliográficos
Autor(a) principal: Machado, Carolina Romero
Data de Publicação: 2013
Outros Autores: Machado, Elizabeth Stankiewicz, Rohloff, Roger Denis, Azevedo, Marina, Campos, Dayse Pereira, Oliveira, Robson Bruniera de, Brasil, Patrícia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35771
Resumo: Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
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spelling Machado, Carolina RomeroMachado, Elizabeth StankiewiczRohloff, Roger DenisAzevedo, MarinaCampos, Dayse PereiraOliveira, Robson Bruniera deBrasil, Patrícia2019-09-23T12:24:31Z2019-09-23T12:24:31Z2013MACHADO, Carolina Romero et al. Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system. Plos Neglected Tropical Diseases, v. 7, n. 5, p. 1-4, May 2013.1935-2727https://www.arca.fiocruz.br/handle/icict/3577110.1371/journal.pntd.00022171935-2735engPublic Library of ScienceIs pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information systeminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Maternidade Municipal Fernando Magalhães. Rio de Janeiro, RJ, Brasil.Secretaria Municipal de Saúde e Defesa Civil do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Background: Dengue is a reportable disease in Brazil; however, pregnancy has been included in the application form of the Brazilian notification information system only after 2006. To estimate the severity of maternal dengue infection, the available data that were compiled from January 2007 to December 2008 by the official surveillance information system of the city of Rio de Janeiro were reviewed. Methods and Principal Findings: During the study period, 151,604 cases of suspected dengue infection were reported. Five hundred sixty-one women in their reproductive age (15–49 years) presented with dengue infection; 99 (18.1%) pregnant and 447 (81.9%) non-pregnant women were analyzed. Dengue cases were categorized using the 1997 WHO classification system, and DHF/DSS were considered severe disease. The Mann-Whitney test was used to compare maternal age, according to gestational period, and severity of disease. A chi-square test was utilized to evaluate the differences in the proportion of dengue severity between pregnant and non-pregnant women. Univariate analysis was performed to compare outcome variables (severe dengue and non-severe dengue) and explanatory variables (pregnancy, gestational age and trimester) using the Wald test. A multivariate analysis was performed to assess the independence of statistically significant variables in the univariate analysis. A p-value,0.05 was considered statistically significant. A higher percentage of severe dengue infection among pregnant women was found, p = 0.0001. Final analysis demonstrated that pregnant women are 3.4 times more prone to developing severe dengue (OR: 3.38; CI: 2.10–5.42). Mortality among pregnant women was superior to non-pregnant women. Conclusion: Pregnant women have an increased risk of developing severe dengue infection and dying of dengue.DenguePregnancyRio de JaneiroBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/35771/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Machado_Carolina_etal_INI_2013.pdfve_Machado_Carolina_etal_INI_2013.pdfapplication/pdf135840https://www.arca.fiocruz.br/bitstream/icict/35771/2/ve_Machado_Carolina_etal_INI_2013.pdf79c6c16b24772eb03b40241fc0a13963MD52TEXTve_Machado_Carolina_etal_INI_2013.pdf.txtve_Machado_Carolina_etal_INI_2013.pdf.txtExtracted texttext/plain20172https://www.arca.fiocruz.br/bitstream/icict/35771/3/ve_Machado_Carolina_etal_INI_2013.pdf.txt199cb5190fb6e613a2ce8c70b8bdb676MD53icict/357712019-09-24 02:03:29.486oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-09-24T05:03:29Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
title Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
spellingShingle Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
Machado, Carolina Romero
Dengue
Pregnancy
Rio de Janeiro
Brazil
title_short Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
title_full Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
title_fullStr Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
title_full_unstemmed Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
title_sort Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system
author Machado, Carolina Romero
author_facet Machado, Carolina Romero
Machado, Elizabeth Stankiewicz
Rohloff, Roger Denis
Azevedo, Marina
Campos, Dayse Pereira
Oliveira, Robson Bruniera de
Brasil, Patrícia
author_role author
author2 Machado, Elizabeth Stankiewicz
Rohloff, Roger Denis
Azevedo, Marina
Campos, Dayse Pereira
Oliveira, Robson Bruniera de
Brasil, Patrícia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machado, Carolina Romero
Machado, Elizabeth Stankiewicz
Rohloff, Roger Denis
Azevedo, Marina
Campos, Dayse Pereira
Oliveira, Robson Bruniera de
Brasil, Patrícia
dc.subject.en.pt_BR.fl_str_mv Dengue
Pregnancy
Rio de Janeiro
Brazil
topic Dengue
Pregnancy
Rio de Janeiro
Brazil
description Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2019-09-23T12:24:31Z
dc.date.available.fl_str_mv 2019-09-23T12:24:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MACHADO, Carolina Romero et al. Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system. Plos Neglected Tropical Diseases, v. 7, n. 5, p. 1-4, May 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35771
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0002217
dc.identifier.eissn.none.fl_str_mv 1935-2735
identifier_str_mv MACHADO, Carolina Romero et al. Is pregnancy associated with severe dengue? A review of data from the Rio de Janeiro surveillance information system. Plos Neglected Tropical Diseases, v. 7, n. 5, p. 1-4, May 2013.
1935-2727
10.1371/journal.pntd.0002217
1935-2735
url https://www.arca.fiocruz.br/handle/icict/35771
dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Public Library of Science
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