RATT: Rapid Annotation Transfer Tool
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/30135 |
Resumo: | Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Parasite genomics. Cambridge, UK. |
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Otto, Thomas D.Dillon, Gary P.Degrave, Wim S.Berriman, Matthew2018-11-22T10:24:33Z2018-11-22T10:24:33Z2011OTTO, Thomas D.; DILLON, Gary P.; DEGRAVE, Win S.; BERRIMAN, Matthew. RATT: Rapid Annotation Transfer Tool. Nucleic Acids Research, v.39, n.9, e57, 7p, Feb. 2011.0305-1048https://www.arca.fiocruz.br/handle/icict/3013510.1093/nar/gkq12681362-4962engOxford University PressFerramenta de Transferência Rápida de AnotaçõesGenomaRapid Annotation Transfer ToolGenomeRATT: Rapid Annotation Transfer Toolinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleWellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Parasite genomics. Cambridge, UK.Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Parasite genomics. Cambridge, UK.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformatica. Rio de Janeiro, RJ, Brasil.Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Parasite genomics. Cambridge, UK.Second-generation sequencing technologies have made large-scale sequencing projects commonplace. However, making use of these datasets often requires gene function to be ascribed genome wide. Although tool development has kept pace with the changes in sequence production, for tasks such as mapping, de novo assembly or visualization, genome annotation remains a challenge. We have developed a method to rapidly provide accurate annotation for new genomes using previously annotated genomes as a reference. The method, implemented in a tool called RATT (Rapid Annotation Transfer Tool), transfers annotations from a high-quality reference to a new genome on the basis of conserved synteny. We demonstrate that a Mycobacterium tuberculosis genome or a single 2.5 Mb chromosome from a malaria parasite can be annotated in less than five minutes with only modest computational resources. RATT is available at http://ratt.sourceforge.net.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30135/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALwin-degrave_etal_IOC_2011.pdfwin-degrave_etal_IOC_2011.pdfapplication/pdf4374503https://www.arca.fiocruz.br/bitstream/icict/30135/2/win-degrave_etal_IOC_2011.pdf18de281af85fb64e34abaece725c18a6MD52TEXTwin-degrave_etal_IOC_2011.pdf.txtwin-degrave_etal_IOC_2011.pdf.txtExtracted texttext/plain29320https://www.arca.fiocruz.br/bitstream/icict/30135/3/win-degrave_etal_IOC_2011.pdf.txt39609bd042bd67746496d7a095816292MD53icict/301352018-11-23 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dc.title.pt_BR.fl_str_mv |
RATT: Rapid Annotation Transfer Tool |
title |
RATT: Rapid Annotation Transfer Tool |
spellingShingle |
RATT: Rapid Annotation Transfer Tool Otto, Thomas D. Ferramenta de Transferência Rápida de Anotações Genoma Rapid Annotation Transfer Tool Genome |
title_short |
RATT: Rapid Annotation Transfer Tool |
title_full |
RATT: Rapid Annotation Transfer Tool |
title_fullStr |
RATT: Rapid Annotation Transfer Tool |
title_full_unstemmed |
RATT: Rapid Annotation Transfer Tool |
title_sort |
RATT: Rapid Annotation Transfer Tool |
author |
Otto, Thomas D. |
author_facet |
Otto, Thomas D. Dillon, Gary P. Degrave, Wim S. Berriman, Matthew |
author_role |
author |
author2 |
Dillon, Gary P. Degrave, Wim S. Berriman, Matthew |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Otto, Thomas D. Dillon, Gary P. Degrave, Wim S. Berriman, Matthew |
dc.subject.other.pt_BR.fl_str_mv |
Ferramenta de Transferência Rápida de Anotações Genoma |
topic |
Ferramenta de Transferência Rápida de Anotações Genoma Rapid Annotation Transfer Tool Genome |
dc.subject.en.pt_BR.fl_str_mv |
Rapid Annotation Transfer Tool Genome |
description |
Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Parasite genomics. Cambridge, UK. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011 |
dc.date.accessioned.fl_str_mv |
2018-11-22T10:24:33Z |
dc.date.available.fl_str_mv |
2018-11-22T10:24:33Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
OTTO, Thomas D.; DILLON, Gary P.; DEGRAVE, Win S.; BERRIMAN, Matthew. RATT: Rapid Annotation Transfer Tool. Nucleic Acids Research, v.39, n.9, e57, 7p, Feb. 2011. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/30135 |
dc.identifier.issn.pt_BR.fl_str_mv |
0305-1048 |
dc.identifier.doi.none.fl_str_mv |
10.1093/nar/gkq1268 |
dc.identifier.eissn.none.fl_str_mv |
1362-4962 |
identifier_str_mv |
OTTO, Thomas D.; DILLON, Gary P.; DEGRAVE, Win S.; BERRIMAN, Matthew. RATT: Rapid Annotation Transfer Tool. Nucleic Acids Research, v.39, n.9, e57, 7p, Feb. 2011. 0305-1048 10.1093/nar/gkq1268 1362-4962 |
url |
https://www.arca.fiocruz.br/handle/icict/30135 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Oxford University Press |
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Oxford University Press |
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