Reticulo-endotheliomatose maligna

Detalhes bibliográficos
Autor(a) principal: Torres, C. Magarinos
Data de Publicação: 1932
Outros Autores: Azevedo, A. Penna de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48024
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
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spelling Torres, C. MagarinosAzevedo, A. Penna de2021-07-06T18:55:26Z2021-07-06T18:55:26Z1932TORRES, C. Magarinos; AZEVEDO, A. Penna de. Reticulo-endotheliomatose maligna. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 26, n. 2, 19 p, Ago. 1932.0074-0276https://www.arca.fiocruz.br/handle/icict/4802410.1590/S0074-027619320002000061678-8060porFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Reticulo-endotheliomatoseMalignaReticulo-endotheliomatose malignainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Resumo A spindle-cell sarcoma (fig. 5) apparently originating from the dura (fig. 4) was found at the autopsy of a male, mulato, 17 years of age. The bones of the skull (occipital and both parietals) were penetrated and destroyed (fig. 1 and 2). The nervous tissue was not penetrated, the only change in the brain being a depressed area where the tumor was included. Metastatic nodules were found in the liver (fig. 3),hepatic lymphnodes (fig. 14), spleen (fig. 12) and suprarenal bodies (fig. 15). The structure, however, in all those different locations was that of a typical endothelioma (figs. 8, 11 and 13). The cells are of large and moderate size, of polyhedral form, with vesicular nuclei, diminutive nucleoli and clear cytoplasm. (Figs. 6 and 8). They are arranged about a central lumen which represents a rudimentary vessel (figs. 9 and 13). Other areas are composed of cells without concentric arrangement (figs. 4 and 10). In small areas, the colums of liver cells are marginated in one side by typical sinusoids, while in the other side tumor cells arranged about a narrow lumen are seen suggesting a pathological (neoplastic) sinusoid (figs. 7 and 9). The case is considered as a multiple diffuse endothelioma. The origin of the tumor is referred to the reticulo-endothelial apparatus of the liver, the spleen, the suprarenal bodies and the lymph nodes, the structure being rather uniform in those organs. In the dura, the endothelioma reproduces the structure and presents the general character of a fibroblastic sarcoma; in some places, however, the structure of endothelioma could be found (fig.6). It corresponds to the reticulo-endotheliomatosis maligna according to Puhr's grouping of progressive changes in the reticulo-endothelial apparatus which is a follows: 1. HYPERPLASTIC - 1. Mnnocytic leukemia. 2. a) Aleukemic reticulosis (Goldschmid and Isaac). b) Idiopathic sarcoma of skin (Kaposi). c) Cutaneous sarcoid (Spiegler). 3. Secretory reticulosis. a) Gaucher's disease. b) Generalized xanthomatosis. c) Spleno-hepatomegaly with lipoidic cells (Pick). II. BLASTOMATOSUS OR NEOPLASTIC - 1. Benign - a) Circumscribed tumors. a) Epulis sarcomatosa; b) Benign giant-cells sarcoma of the bone - marrow of long bones. b) Generalized brown tumors of osteitis fibrosa. 2. Malignant - a) Circumscribed haemangio - endothelioma (reticulo- endothelioma (maligum). of {liver, spleen, bone-marrow. b) Generalized haemangio-endotheliomatosis (reticulo-endotheliomatosis maligna) (Grabowski).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48024/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMagarinosTorres_APAzevedo_IOC_v26n2_1932.pdfMagarinosTorres_APAzevedo_IOC_v26n2_1932.pdfapplication/pdf5065644https://www.arca.fiocruz.br/bitstream/icict/48024/2/MagarinosTorres_APAzevedo_IOC_v26n2_1932.pdf1c8cf1cbd045e5fe30007d6a32f616afMD52TEXTMagarinosTorres_APAzevedo_IOC_v26n2_1932.pdf.txtMagarinosTorres_APAzevedo_IOC_v26n2_1932.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Reticulo-endotheliomatose maligna
title Reticulo-endotheliomatose maligna
spellingShingle Reticulo-endotheliomatose maligna
Torres, C. Magarinos
Reticulo-endotheliomatose
Maligna
title_short Reticulo-endotheliomatose maligna
title_full Reticulo-endotheliomatose maligna
title_fullStr Reticulo-endotheliomatose maligna
title_full_unstemmed Reticulo-endotheliomatose maligna
title_sort Reticulo-endotheliomatose maligna
author Torres, C. Magarinos
author_facet Torres, C. Magarinos
Azevedo, A. Penna de
author_role author
author2 Azevedo, A. Penna de
author2_role author
dc.contributor.author.fl_str_mv Torres, C. Magarinos
Azevedo, A. Penna de
dc.subject.other.pt_BR.fl_str_mv Reticulo-endotheliomatose
Maligna
topic Reticulo-endotheliomatose
Maligna
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
publishDate 1932
dc.date.issued.fl_str_mv 1932
dc.date.accessioned.fl_str_mv 2021-07-06T18:55:26Z
dc.date.available.fl_str_mv 2021-07-06T18:55:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TORRES, C. Magarinos; AZEVEDO, A. Penna de. Reticulo-endotheliomatose maligna. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 26, n. 2, 19 p, Ago. 1932.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48024
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761932000200006
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv TORRES, C. Magarinos; AZEVEDO, A. Penna de. Reticulo-endotheliomatose maligna. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 26, n. 2, 19 p, Ago. 1932.
0074-0276
10.1590/S0074-02761932000200006
1678-8060
url https://www.arca.fiocruz.br/handle/icict/48024
dc.language.iso.fl_str_mv por
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
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