Acute tubular necrosis and renal failure in patients with glomerular

Detalhes bibliográficos
Autor(a) principal: Tavares, Maria Brandão
Data de Publicação: 2012
Outros Autores: Almeida, Maria da Conceição Chagas de, Martins, Reyla Tarita Cruz, Sousa, Ana Carolina Gil Pinho de, Martinelli, Reinaldo, dosSantos, Washington Luis Conrado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7239
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
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spelling Tavares, Maria BrandãoAlmeida, Maria da Conceição Chagas deMartins, Reyla Tarita CruzSousa, Ana Carolina Gil Pinho deMartinelli, ReinaldodosSantos, Washington Luis Conrado2013-11-20T14:34:48Z2013-11-20T14:34:48Z2012TAVARES, M. B. et al. Acute tubular necrosis and renal failure in patients with glomerular disease. Renal Failure, v. 34, n. 10, p. 1252–1257, 2012.0886-022Xhttps://www.arca.fiocruz.br/handle/icict/723910.3109/0886022X.2012.723582engInforma Healthcare USA, IncAcute tubular necrosis and renal failure in patients with glomerularinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Departamento de Medicina. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Departamento de Medicina. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina. Departamento de Medicina. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilRenal failure is common in patients with glomerular disease. Although renal failure may result from the glomerular lesion itself, it is also observed in patients with minimal glomerular alterations. Degenerative changes and necrosis of the tubular epithelium are common findings in kidney biopsies from these patients. The aim of this work is to examine the association between acute tubular necrosis (ATN) and renal failure in patients with glomerulopathy and to estimate the relationship between the degree of ATN and renal failure in these patients. Data on age, sex, presence of nephrotic syndrome, and renal failure were recorded for 149 patients, who underwent a renal biopsy for the diagnosis of glomerulopathy. The biopsies were reviewed, and ATN, when present, was classified as one of four grades depending on its intensity. The mean age of the patients was 21 16 years. Eighty patients (54%) were male, 43 (42%) had renal failure, 104 (72%) had nephrotic syndrome, and 66 (45%) had minimal change disease or focal segmental glomerulosclerosis. ATN was present in 115 (77%) patients. The frequency of renal failure was directly correlated with the intensity of ATN [odds ratio (OR) of 26.0 for patients with grade 2 lesions and OR of 45.5 for patients with grade 3 lesions]. ATN is a common finding in the biopsies of patients with glomerulopathy. The severity of ATN is directly associated with the frequency of renal failure in these patients.Acute kidney injuryAcute tubular necrosisGlomerular disease,Nephrotic syndromeHistological scoreHistopathologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALTavares MB Acute tubular....pdfTavares MB Acute tubular....pdfapplication/pdf20715692https://www.arca.fiocruz.br/bitstream/icict/7239/1/Tavares%20MB%20Acute%20tubular....pdfaa0439232cd45b2020382475589425ebMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81867https://www.arca.fiocruz.br/bitstream/icict/7239/2/license.txt89d048e714e969a1adcda05fdb1978beMD52TEXTTavares MB Acute tubular....pdf.txtTavares MB Acute tubular....pdf.txtExtracted texttext/plain26037https://www.arca.fiocruz.br/bitstream/icict/7239/5/Tavares%20MB%20Acute%20tubular....pdf.txt78926c987950c880f99e4d296deeaf0aMD55THUMBNAILTavares MB Acute tubular....pdf.jpgTavares MB Acute tubular....pdf.jpgGenerated Thumbnailimage/jpeg2526https://www.arca.fiocruz.br/bitstream/icict/7239/4/Tavares%20MB%20Acute%20tubular....pdf.jpg624ee56dc2bf3ffcb84363908397df39MD54icict/72392023-03-15 14:32:59.49oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Acute tubular necrosis and renal failure in patients with glomerular
title Acute tubular necrosis and renal failure in patients with glomerular
spellingShingle Acute tubular necrosis and renal failure in patients with glomerular
Tavares, Maria Brandão
Acute kidney injury
Acute tubular necrosis
Glomerular disease,
Nephrotic syndrome
Histological score
Histopathology
title_short Acute tubular necrosis and renal failure in patients with glomerular
title_full Acute tubular necrosis and renal failure in patients with glomerular
title_fullStr Acute tubular necrosis and renal failure in patients with glomerular
title_full_unstemmed Acute tubular necrosis and renal failure in patients with glomerular
title_sort Acute tubular necrosis and renal failure in patients with glomerular
author Tavares, Maria Brandão
author_facet Tavares, Maria Brandão
Almeida, Maria da Conceição Chagas de
Martins, Reyla Tarita Cruz
Sousa, Ana Carolina Gil Pinho de
Martinelli, Reinaldo
dosSantos, Washington Luis Conrado
author_role author
author2 Almeida, Maria da Conceição Chagas de
Martins, Reyla Tarita Cruz
Sousa, Ana Carolina Gil Pinho de
Martinelli, Reinaldo
dosSantos, Washington Luis Conrado
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Tavares, Maria Brandão
Almeida, Maria da Conceição Chagas de
Martins, Reyla Tarita Cruz
Sousa, Ana Carolina Gil Pinho de
Martinelli, Reinaldo
dosSantos, Washington Luis Conrado
dc.subject.en.pt_BR.fl_str_mv Acute kidney injury
Acute tubular necrosis
Glomerular disease,
Nephrotic syndrome
Histological score
Histopathology
topic Acute kidney injury
Acute tubular necrosis
Glomerular disease,
Nephrotic syndrome
Histological score
Histopathology
description Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2013-11-20T14:34:48Z
dc.date.available.fl_str_mv 2013-11-20T14:34:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TAVARES, M. B. et al. Acute tubular necrosis and renal failure in patients with glomerular disease. Renal Failure, v. 34, n. 10, p. 1252–1257, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7239
dc.identifier.issn.none.fl_str_mv 0886-022X
dc.identifier.doi.none.fl_str_mv 10.3109/0886022X.2012.723582
identifier_str_mv TAVARES, M. B. et al. Acute tubular necrosis and renal failure in patients with glomerular disease. Renal Failure, v. 34, n. 10, p. 1252–1257, 2012.
0886-022X
10.3109/0886022X.2012.723582
url https://www.arca.fiocruz.br/handle/icict/7239
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Informa Healthcare USA, Inc
publisher.none.fl_str_mv Informa Healthcare USA, Inc
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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