Adverse effects of levomepromazine in sheep

Detalhes bibliográficos
Autor(a) principal: Lau, Hugo Didonet
Data de Publicação: 2014
Outros Autores: Fan, Luiz Carlos Ribeiro, Fialho, Sérgio Amaro Guimarães, Pippi, Ney Luis, Raiser, Alceu Gaspar
Tipo de documento: Artigo
Idioma: por
Título da fonte: Pesquisa Agropecuária Brasileira (Online)
Texto Completo: https://seer.sct.embrapa.br/index.php/pab/article/view/15177
Resumo: Change of hemogram, cardiopulmonary frequency, rectal temperature and rumen motility was studied prior and post application of levomepromazine in eight sheep divided into two groups of equal number. The first group received intramuscularly (2 mg/kg) and the second intravenously (1 mg/kg). The blood samples and the clinical symptoms were gathered prior. 15, 30 and 60 minutes post the drug application. In all animals a decrease of erythrocyte number (8.57 - 7.32 million/mm3) and haematocrit values (32.37 - 27.12%) was observed. Eosinopenia (708.75 - 452.50 mm3) and neutrophilia (2,337.50 - 3,345.00 mm3) were also observed. The leukocytes and lymphocytes counts remained constant. The cardiac and pulmonary frequency decreased 15 minutes after the drug application (130 - 118 bat./min and 97.60 - 49.87 mov./min.). After this time increase (132- 143 bat./min. and 60.00-68.75 mov./min.) was observed. The rectal temperature and rumem motility rate remained practically constant during the experiment.
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spelling Adverse effects of levomepromazine in sheepEfeitos adversos da levomepromazina em ovinoshemogram; cardiopulmonary frequency; rectal temperature; haematocrithemograma; frequência cardiorrespiratória; temperatura retal; hematócritoChange of hemogram, cardiopulmonary frequency, rectal temperature and rumen motility was studied prior and post application of levomepromazine in eight sheep divided into two groups of equal number. The first group received intramuscularly (2 mg/kg) and the second intravenously (1 mg/kg). The blood samples and the clinical symptoms were gathered prior. 15, 30 and 60 minutes post the drug application. In all animals a decrease of erythrocyte number (8.57 - 7.32 million/mm3) and haematocrit values (32.37 - 27.12%) was observed. Eosinopenia (708.75 - 452.50 mm3) and neutrophilia (2,337.50 - 3,345.00 mm3) were also observed. The leukocytes and lymphocytes counts remained constant. The cardiac and pulmonary frequency decreased 15 minutes after the drug application (130 - 118 bat./min and 97.60 - 49.87 mov./min.). After this time increase (132- 143 bat./min. and 60.00-68.75 mov./min.) was observed. The rectal temperature and rumem motility rate remained practically constant during the experiment.Variações do hemograma, frequência cardiorrespiratória, temperatura retal e movimentos ruminatórios foram estudados, antes e após a aplicação de levomepromazina em oito ovinos separados em dois lotes de igual número. O primeiro lote recebeu a droga por via intramuscular (2 mg/kg) e o segundo pela via intravenosa (1 mg/kg). As amostras sanguíneas e os sintomas clínicos foram colhidos antes e aos 15, 30 e 60 minutos após a aplicação do fármaco. Em todos os animais evidenciou-se a diminuição do número de eritrócitos (8,57 - 7,32 milhões/mm3) e dos valores do hematócrito (32,37 - 27,12%), eosinopenia (708,75 - 452,50 mm3) e neutrofilia (2.337,50 - 3.345,00 mm3). A taxa de leucócitos e linfócitos permaneceu praticamente constante. A frequência cardíaca e respiratória diminuiu nos primeiros 15 minutos (130 - 118 bat./min. e 97,50 - 49,87 mov./min.), aumentando logo após (132 - 143 bat./min. e 60,00 - 68,75 mov./min.). A temperatura retal e os movimentos de rúmen permaneceram sem alteração.Pesquisa Agropecuaria BrasileiraPesquisa Agropecuária BrasileiraLau, Hugo DidonetFan, Luiz Carlos RibeiroFialho, Sérgio Amaro GuimarãesPippi, Ney LuisRaiser, Alceu Gaspar2014-04-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.sct.embrapa.br/index.php/pab/article/view/15177Pesquisa Agropecuaria Brasileira; v.18, n.2, fev. 1983; 181-185Pesquisa Agropecuária Brasileira; v.18, n.2, fev. 1983; 181-1851678-39210100-104xreponame:Pesquisa Agropecuária Brasileira (Online)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPAporhttps://seer.sct.embrapa.br/index.php/pab/article/view/15177/8989info:eu-repo/semantics/openAccess2014-04-16T18:50:36Zoai:ojs.seer.sct.embrapa.br:article/15177Revistahttp://seer.sct.embrapa.br/index.php/pabPRIhttps://old.scielo.br/oai/scielo-oai.phppab@sct.embrapa.br || sct.pab@embrapa.br1678-39210100-204Xopendoar:2014-04-16T18:50:36Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Adverse effects of levomepromazine in sheep
Efeitos adversos da levomepromazina em ovinos
title Adverse effects of levomepromazine in sheep
spellingShingle Adverse effects of levomepromazine in sheep
Lau, Hugo Didonet
hemogram; cardiopulmonary frequency; rectal temperature; haematocrit
hemograma; frequência cardiorrespiratória; temperatura retal; hematócrito
title_short Adverse effects of levomepromazine in sheep
title_full Adverse effects of levomepromazine in sheep
title_fullStr Adverse effects of levomepromazine in sheep
title_full_unstemmed Adverse effects of levomepromazine in sheep
title_sort Adverse effects of levomepromazine in sheep
author Lau, Hugo Didonet
author_facet Lau, Hugo Didonet
Fan, Luiz Carlos Ribeiro
Fialho, Sérgio Amaro Guimarães
Pippi, Ney Luis
Raiser, Alceu Gaspar
author_role author
author2 Fan, Luiz Carlos Ribeiro
Fialho, Sérgio Amaro Guimarães
Pippi, Ney Luis
Raiser, Alceu Gaspar
author2_role author
author
author
author
dc.contributor.none.fl_str_mv

dc.contributor.author.fl_str_mv Lau, Hugo Didonet
Fan, Luiz Carlos Ribeiro
Fialho, Sérgio Amaro Guimarães
Pippi, Ney Luis
Raiser, Alceu Gaspar
dc.subject.por.fl_str_mv hemogram; cardiopulmonary frequency; rectal temperature; haematocrit
hemograma; frequência cardiorrespiratória; temperatura retal; hematócrito
topic hemogram; cardiopulmonary frequency; rectal temperature; haematocrit
hemograma; frequência cardiorrespiratória; temperatura retal; hematócrito
description Change of hemogram, cardiopulmonary frequency, rectal temperature and rumen motility was studied prior and post application of levomepromazine in eight sheep divided into two groups of equal number. The first group received intramuscularly (2 mg/kg) and the second intravenously (1 mg/kg). The blood samples and the clinical symptoms were gathered prior. 15, 30 and 60 minutes post the drug application. In all animals a decrease of erythrocyte number (8.57 - 7.32 million/mm3) and haematocrit values (32.37 - 27.12%) was observed. Eosinopenia (708.75 - 452.50 mm3) and neutrophilia (2,337.50 - 3,345.00 mm3) were also observed. The leukocytes and lymphocytes counts remained constant. The cardiac and pulmonary frequency decreased 15 minutes after the drug application (130 - 118 bat./min and 97.60 - 49.87 mov./min.). After this time increase (132- 143 bat./min. and 60.00-68.75 mov./min.) was observed. The rectal temperature and rumem motility rate remained practically constant during the experiment.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-16
dc.type.none.fl_str_mv
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/15177
url https://seer.sct.embrapa.br/index.php/pab/article/view/15177
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/15177/8989
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
dc.source.none.fl_str_mv Pesquisa Agropecuaria Brasileira; v.18, n.2, fev. 1983; 181-185
Pesquisa Agropecuária Brasileira; v.18, n.2, fev. 1983; 181-185
1678-3921
0100-104x
reponame:Pesquisa Agropecuária Brasileira (Online)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Agropecuária Brasileira (Online)
collection Pesquisa Agropecuária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv pab@sct.embrapa.br || sct.pab@embrapa.br
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