Effects of anthocyanin on intestinal health: a systematic review.
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
Texto Completo: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1131723 https://doi.org/10.3390/nu13041331 |
Resumo: | Intestinal health relies on the association between the mucosal immune system, intestinal barrier and gut microbiota. Bioactive components that affect the gut microbiota composition, epithelial physical barrier and intestinal morphology were previously studied. The current systematic review evaluated evidence of anthocyanin effects and the ability to improve gut microbiota composition, their metabolites and parameters of the physical barrier; this was conducted in order to answer the question: ?Does food source or extract of anthocyanin promote changes on intestinal parameters??. The data analysis was conducted following the PRISMA guidelines with the search performed at PubMed, Cochrane and Scopus databases for experimental studies, and the risk of bias was assessed by the SYRCLE tool. Twenty-seven studies performed in animal models were included, and evaluated for limitations in heterogeneity, methodologies, absence of information regarding allocation process and investigators? blinding. The data were analyzed, and the anthocyanin supplementation demonstrated positive effects on intestinal health. The main results identified were an increase of Bacteroidetes and a decrease of Firmicutes, an increase of short chain fatty acids production, a decrease of intestinal pH and intestinal permeability, an increase of the number of goblet cells and tight junction proteins and villi improvement in length or height. Thus, the anthocyanin supplementation has a potential effect to improve the intestinal health. PROSPERO (CRD42020204835). |
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Effects of anthocyanin on intestinal health: a systematic review.MicrobiotaPolifenóisBarreira intestinalSaúde intestinalAntocianinaIntestinal health relies on the association between the mucosal immune system, intestinal barrier and gut microbiota. Bioactive components that affect the gut microbiota composition, epithelial physical barrier and intestinal morphology were previously studied. The current systematic review evaluated evidence of anthocyanin effects and the ability to improve gut microbiota composition, their metabolites and parameters of the physical barrier; this was conducted in order to answer the question: ?Does food source or extract of anthocyanin promote changes on intestinal parameters??. The data analysis was conducted following the PRISMA guidelines with the search performed at PubMed, Cochrane and Scopus databases for experimental studies, and the risk of bias was assessed by the SYRCLE tool. Twenty-seven studies performed in animal models were included, and evaluated for limitations in heterogeneity, methodologies, absence of information regarding allocation process and investigators? blinding. The data were analyzed, and the anthocyanin supplementation demonstrated positive effects on intestinal health. The main results identified were an increase of Bacteroidetes and a decrease of Firmicutes, an increase of short chain fatty acids production, a decrease of intestinal pH and intestinal permeability, an increase of the number of goblet cells and tight junction proteins and villi improvement in length or height. Thus, the anthocyanin supplementation has a potential effect to improve the intestinal health. PROSPERO (CRD42020204835).THAÍSA AGRIZZI VEREDIANO, Universidade Federal de Viçosa; HÉRCIA STAMPINI DUARTE MARTINO, Universidade Federal de Viçosa; MARIA CRISTINA DIAS PAES, CNPMS; ELAD TAKO, Cornell University.VEREDIANO, T. A.MARTINO, H. S. D.PAES, M. C. D.TAKO, E.2021-05-07T13:32:25Z2021-05-07T13:32:25Z2021-05-072021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleNutrients, v. 13, 1331, 2021.http://www.alice.cnptia.embrapa.br/alice/handle/doc/1131723https://doi.org/10.3390/nu13041331porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2021-05-07T13:32:34Zoai:www.alice.cnptia.embrapa.br:doc/1131723Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542021-05-07T13:32:34falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542021-05-07T13:32:34Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false |
dc.title.none.fl_str_mv |
Effects of anthocyanin on intestinal health: a systematic review. |
title |
Effects of anthocyanin on intestinal health: a systematic review. |
spellingShingle |
Effects of anthocyanin on intestinal health: a systematic review. VEREDIANO, T. A. Microbiota Polifenóis Barreira intestinal Saúde intestinal Antocianina |
title_short |
Effects of anthocyanin on intestinal health: a systematic review. |
title_full |
Effects of anthocyanin on intestinal health: a systematic review. |
title_fullStr |
Effects of anthocyanin on intestinal health: a systematic review. |
title_full_unstemmed |
Effects of anthocyanin on intestinal health: a systematic review. |
title_sort |
Effects of anthocyanin on intestinal health: a systematic review. |
author |
VEREDIANO, T. A. |
author_facet |
VEREDIANO, T. A. MARTINO, H. S. D. PAES, M. C. D. TAKO, E. |
author_role |
author |
author2 |
MARTINO, H. S. D. PAES, M. C. D. TAKO, E. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
THAÍSA AGRIZZI VEREDIANO, Universidade Federal de Viçosa; HÉRCIA STAMPINI DUARTE MARTINO, Universidade Federal de Viçosa; MARIA CRISTINA DIAS PAES, CNPMS; ELAD TAKO, Cornell University. |
dc.contributor.author.fl_str_mv |
VEREDIANO, T. A. MARTINO, H. S. D. PAES, M. C. D. TAKO, E. |
dc.subject.por.fl_str_mv |
Microbiota Polifenóis Barreira intestinal Saúde intestinal Antocianina |
topic |
Microbiota Polifenóis Barreira intestinal Saúde intestinal Antocianina |
description |
Intestinal health relies on the association between the mucosal immune system, intestinal barrier and gut microbiota. Bioactive components that affect the gut microbiota composition, epithelial physical barrier and intestinal morphology were previously studied. The current systematic review evaluated evidence of anthocyanin effects and the ability to improve gut microbiota composition, their metabolites and parameters of the physical barrier; this was conducted in order to answer the question: ?Does food source or extract of anthocyanin promote changes on intestinal parameters??. The data analysis was conducted following the PRISMA guidelines with the search performed at PubMed, Cochrane and Scopus databases for experimental studies, and the risk of bias was assessed by the SYRCLE tool. Twenty-seven studies performed in animal models were included, and evaluated for limitations in heterogeneity, methodologies, absence of information regarding allocation process and investigators? blinding. The data were analyzed, and the anthocyanin supplementation demonstrated positive effects on intestinal health. The main results identified were an increase of Bacteroidetes and a decrease of Firmicutes, an increase of short chain fatty acids production, a decrease of intestinal pH and intestinal permeability, an increase of the number of goblet cells and tight junction proteins and villi improvement in length or height. Thus, the anthocyanin supplementation has a potential effect to improve the intestinal health. PROSPERO (CRD42020204835). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-07T13:32:25Z 2021-05-07T13:32:25Z 2021-05-07 2021 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Nutrients, v. 13, 1331, 2021. http://www.alice.cnptia.embrapa.br/alice/handle/doc/1131723 https://doi.org/10.3390/nu13041331 |
identifier_str_mv |
Nutrients, v. 13, 1331, 2021. |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1131723 https://doi.org/10.3390/nu13041331 |
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por |
language |
por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
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Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
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EMBRAPA |
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Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
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Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
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Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
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cg-riaa@embrapa.br |
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