Mast cell changes in experimental diabetes: focus on attenuation of allergic events

Detalhes bibliográficos
Autor(a) principal: Carvalho,Vinicius F
Data de Publicação: 2005
Outros Autores: Barreto,Emiliano O, Cordeiro,Renato SB, Lagente,Vincent, Martins,Marco A, e Silva,Patrícia MR
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900021
Resumo: The prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
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spelling Mast cell changes in experimental diabetes: focus on attenuation of allergic eventsdiabetesallergymast cellsglucocorticoidsThe prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.Instituto Oswaldo Cruz, Ministério da Saúde2005-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900021Memórias do Instituto Oswaldo Cruz v.100 suppl.1 2005reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762005000900021info:eu-repo/semantics/openAccessCarvalho,Vinicius FBarreto,Emiliano OCordeiro,Renato SBLagente,VincentMartins,Marco Ae Silva,Patrícia MReng2020-04-25T17:49:31Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:13:32.27Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Mast cell changes in experimental diabetes: focus on attenuation of allergic events
title Mast cell changes in experimental diabetes: focus on attenuation of allergic events
spellingShingle Mast cell changes in experimental diabetes: focus on attenuation of allergic events
Carvalho,Vinicius F
diabetes
allergy
mast cells
glucocorticoids
title_short Mast cell changes in experimental diabetes: focus on attenuation of allergic events
title_full Mast cell changes in experimental diabetes: focus on attenuation of allergic events
title_fullStr Mast cell changes in experimental diabetes: focus on attenuation of allergic events
title_full_unstemmed Mast cell changes in experimental diabetes: focus on attenuation of allergic events
title_sort Mast cell changes in experimental diabetes: focus on attenuation of allergic events
author Carvalho,Vinicius F
author_facet Carvalho,Vinicius F
Barreto,Emiliano O
Cordeiro,Renato SB
Lagente,Vincent
Martins,Marco A
e Silva,Patrícia MR
author_role author
author2 Barreto,Emiliano O
Cordeiro,Renato SB
Lagente,Vincent
Martins,Marco A
e Silva,Patrícia MR
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Carvalho,Vinicius F
Barreto,Emiliano O
Cordeiro,Renato SB
Lagente,Vincent
Martins,Marco A
e Silva,Patrícia MR
dc.subject.por.fl_str_mv diabetes
allergy
mast cells
glucocorticoids
topic diabetes
allergy
mast cells
glucocorticoids
dc.description.none.fl_txt_mv The prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
description The prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
publishDate 2005
dc.date.none.fl_str_mv 2005-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900021
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762005000900021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.100 suppl.1 2005
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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